The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Smad transcription factors
Open accessAbstract
Smad transcription factors lie at the core of one of the most versatile cytokine signaling pathways in metazoan biology—the transforming growth factor-β (TGFβ) pathway. Recent progress has shed light into the processes of Smad activation and deactivation, nucleocytoplasmic dynamics, and assembly of transcriptional complexes. A rich repertoire of regulatory devices exerts control over each step of the Smad pathway. This knowledge is enabling work on more complex questions about the organization, integration, and modulation of Smad-dependent transcriptional programs. We are beginning to uncover self-enabled gene response cascades, graded Smad response mechanisms, and Smad-dependent synexpression groups. Our growing understanding of TGFβ signaling through the Smad pathway provides general principles for how animal cells translate complex inputs into concrete behavior.
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Cites
TGF-β Signaling in Tumor Suppression and Cancer Progression
Derynck, R., Akhurst, R. J., & Balmain, A. (2001) · Nature Genetics · doi:10.1038/ng1001-117 · Cited by 2,275
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription
Zhang, Y., Feng, X.-H., & Derynck, R. (1998) · Nature · doi:10.1038/29814 · Cited by 809
Liu, D., Black, B. L., & Derynck, R. (2001) · Genes & Development · doi:10.1101/gad.925901 · Cited by 399
Identification of Sef, a novel modulator of FGF signalling
Tsang, M., Friesel, R., Kudoh, T., & Dawid, I. B. (2002) · Nature Cell Biology · doi:10.1038/ncb749 · Cited by 304
López-Rovira, T., Chalaux, E., Massagué, J., Rosa, J. L., & Ventura, F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106826200 · Cited by 285
Self-citationThe Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
Dyson, S., & Gurdon, J. B. (1998) · Cell · doi:10.1016/s0092-8674(00)81185-x · Cited by 204
TGIF2 Interacts with Histone Deacetylase 1 and Represses Transcription
Melhuish, T. A., Gallo, C. M., & Wotton, D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103377200 · Cited by 137
Self-citation
Cited by
Massagué, J. (2008) · Cell · doi:10.1016/j.cell.2008.07.001 · Cited by 3,907
Self-citationAdipocyte differentiation from the inside out
Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2066 · Cited by 2,607
IL-17 family cytokines and the expanding diversity of effector T cell lineages
Weaver, C. T., Hatton, R. D., Mangan, P. R., & Harrington, L. E. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141557 · Cited by 1,842
Formation and function of the myofibroblast during tissue repair
Hinz, B. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700613 · Cited by 1,658
Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver
Huch, M., Gehart, H., van Boxtel, R., Hamer, K., Blokzijl, F., Verstegen, M. M. A., Ellis, E., van Wenum, M., Fuchs, S. A., de Ligt, J., et al. (2015) · Cell · doi:10.1016/j.cell.2014.11.050 · Cited by 1,619
Metadata
- Authors
- Massagué, J., Seoane, J., & Wotton, D.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2005-12-01
- Volume
- 19
- Issue
- 23
- Pages
- 2783-2810
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2095605427
- Cited by
- 2,452
- References
- 7
- Type
- posted content
- Language
- en
- Open access
- diamond
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
