The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Pattern formation via small RNA mobility
Open accessAbstract
MicroRNAs and trans-acting siRNAs (ta-siRNAs) have important regulatory roles in development. Unlike other developmentally important regulatory molecules, small RNAs are not known to act as mobile signals during development. Here, we show that low-abundant, conserved ta-siRNAs, termed tasiR-ARFs, move intercellularly from their defined source of biogenesis on the upper (adaxial) side of leaves to the lower (abaxial) side to create a gradient of small RNAs that patterns the abaxial determinant AUXIN RESPONSE FACTOR3. Our observations have important ramifications for the function of small RNAs and suggest they can serve as mobile, instructive signals during development.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Gateway Cloning Vector Set for High-Throughput Functional Analysis of Genes in Planta
Curtis, M. D., & Grossniklaus, U. (2003) · Plant Physiology · doi:10.1104/pp.103.027979 · Cited by 2,644
microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants
Allen, E., Xie, Z., Gustafson, A. M., & Carrington, J. C. (2005) · Cell · doi:10.1016/j.cell.2005.04.004 · Cited by 2,268
Self-citationMicroRNA Expression in Zebrafish Embryonic Development
Wienholds, E., Kloosterman, W. P., Miska, E., Alvarez-Saavedra, E., Berezikov, E., de Bruijn, E., Horvitz, H. R., Kauppinen, S., & Plasterk, R. H. A. (2005) · Science · doi:10.1126/science.1114519 · Cited by 1,551
Selective Blockade of MicroRNA Processing by Lin28
Viswanathan, S. R., Daley, G. Q., & Gregory, R. I. (2008) · Science · doi:10.1126/science.1154040 · Cited by 1,437
Peragine, A., Yoshikawa, M., Wu, G., Albrecht, H. L., & Poethig, R. S. (2004) · Genes & Development · doi:10.1101/gad.1231804 · Cited by 930
Endogenous trans-Acting siRNAs Regulate the Accumulation of Arabidopsis mRNAs
Vazquez, F., Vaucheret, H., Rajagopalan, R., Lepers, C., Gasciolli, V., Mallory, A. C., Hilbert, J.-L., Bartel, D. P., & Crété, P. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.09.028 · Cited by 801
Endogenous siRNA and miRNA Targets Identified by Sequencing of the Arabidopsis Degradome
Addo-Quaye, C., Eshoo, T. W., Bartel, D. P., & Axtell, M. J. (2008) · Current Biology · doi:10.1016/j.cub.2008.04.042 · Cited by 786
Montgomery, T. A., Howell, M. D., Cuperus, J. T., Li, D., Hansen, J. E., Alexander, A. L., Chapman, E. J., Fahlgren, N., Allen, E., & Carrington, J. C. (2008) · Cell · doi:10.1016/j.cell.2008.02.033 · Cited by 774
Self-citationmicroRNA-mediated repression of rolled leaf1 specifies maize leaf polarity
Juarez, M. T., Kui, J. S., Thomas, J., Heller, B. A., & Timmermans, M. C. P. (2004) · Nature · doi:10.1038/nature02363 · Cited by 713
Self-citationA Two-Hit Trigger for siRNA Biogenesis in Plants
Axtell, M. J., Jan, C., Rajagopalan, R., & Bartel, D. P. (2006) · Cell · doi:10.1016/j.cell.2006.09.032 · Cited by 662
Cited by
Cell Signalling by MicroRNA165/6 Directs Gene Dose-Dependent Root Cell Fate
Carlsbecker, A., Lee, J.-Y., Roberts, C. J., Dettmer, J., Lehesranta, S., Zhou, J., Lindgren, O., Moreno-Risueno, M. A., Vatén, A., Thitamadee, S., et al. (2010) · Nature · doi:10.1038/nature08977 · Cited by 861
Small RNA Duplexes Function as Mobile Silencing Signals Between Plant Cells
Dunoyer, P., Schott, G., Himber, C., Meyer, D., Takeda, A., Carrington, J. C., & Voinnet, O. (2010) · Science · doi:10.1126/science.1185880 · Cited by 353
Self-citationRetractedChitwood, D. H., & Timmermans, M. C. P. (2010) · Nature · doi:10.1038/nature09351 · Cited by 262
Self-citationYadav, A., Mathan, J., Dubey, A. K., & Singh, A. (2024) · Non-Coding RNA · doi:10.3390/ncrna10010013 · Cited by 83
Metadata
- Authors
- Chitwood, D. H., Nogueira, F. T. S., Howell, M. D., Montgomery, T. A., Carrington, J. C., & Timmermans, M. C. P.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2009-03-01
- Volume
- 23
- Issue
- 5
- Pages
- 549-554
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2031508869
- Cited by
- 398
- References
- 28
- Type
- posted content
- Language
- en
- Open access
- diamond
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Pattern formation via small RNA mobility. https://app.cochat.ai/papers/10.1101/gad.1770009
- The paper
- Chitwood, D. H., Nogueira, F. T. S., Howell, M. D., Montgomery, T. A., Carrington, J. C., & Timmermans, M. C. P. (2009). Pattern formation via small RNA mobility. Genes & Development. https://doi.org/10.1101/gad.1770009
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
