Mitochondrial biogenesis and dynamics in the developing and diseased heart

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

Issemann, I., & Green, S. (1990) · Nature · doi:10.1038/347645a0 · Cited by 3,519

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature · doi:10.1038/nature07813 · Cited by 3,300

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Jäger, S., Handschin, C., St.-Pierre, J., & Spiegelman, B. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705070104 · Cited by 2,491

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

Pickrell, A. M., & Youle, R. J. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.007 · Cited by 2,310

Myocardial Substrate Metabolism in the Normal and Failing Heart

Stanley, W. C., Recchia, F. A., & Lopaschuk, G. D. (2005) · Physiological Reviews · doi:10.1152/physrev.00006.2004 · Cited by 2,095

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

Pagliarini, D. J., Calvo, S. E., Chang, B., Sheth, S. A., Vafai, S. B., Ong, S.-E., Walford, G. A., Sugiana, C., Boneh, A., Chen, W. K., et al. (2008) · Cell · doi:10.1016/j.cell.2008.06.016 · Cited by 1,994

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

Clark, I. E., Dodson, M. W., Jiang, C., Cao, J. H., Huh, J. R., Seol, J. H., Yoo, S. J., Hay, B. A., & Guo, M. (2006) · Nature · doi:10.1038/nature04779 · Cited by 1,788

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

Park, J., Lee, S. B., Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J.-M., et al. (2006) · Nature · doi:10.1038/nature04788 · Cited by 1,705

Inter-Organelle Crosstalk in Oxidative Distress: A Unified TRPM2-NOX2 Mediated Vicious Cycle Involving Ca2+, Zn2+, and ROS Amplification

Shitaw, E. E., AlAhmad, M., & Sivaprasadarao, A. (2025) · Antioxidants · doi:10.3390/antiox14070776 · Cited by 26

A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells

Turner, D. J., Saveliev, A., Salerno, F., Matheson, L. S., Screen, M., Lawson, H., Wotherspoon, D., Kranc, K. R., & Turner, M. (2022) · eLife · doi:10.7554/elife.72313 · Cited by 23

Tomatidine-stimulated maturation of human embryonic stem cell-derived cardiomyocytes for modeling mitochondrial dysfunction

Kim, Y. S., Yoon, J. W., Kim, D., Choi, S., Kim, H. K., Youm, J. B., Han, J., Heo, S. C., Hyun, S., Seo, J.-W., et al. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-022-00746-8 · Cited by 25

Role of Mitochondrial Dynamics in Cocaine’s Neurotoxicity

Wen, S., Aki, T., Funakoshi, T., Unuma, K., & Uemura, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105418 · Cited by 25

Outcomes of hypothalamic oxytocin neuron-driven cardioprotection after acute myocardial infarction

Schunke, K. J., Rodriguez, J., Dyavanapalli, J., Schloen, J., Wang, X., Escobar, J. B., Kowalik, G., Cheung, E. C., Ribeiro, C., Russo, R., et al. (2023) · Basic Research in Cardiology · doi:10.1007/s00395-023-01013-1 · Cited by 26

PPARα Is Necessary for Radiation-Induced Activation of Noncanonical TGFβ Signaling in the Heart

Subramanian, V., Borchard, S., Azimzadeh, O., Sievert, W., Merl‐Pham, J., Mancuso, M., Pasquali, E., Multhoff, G., Popper, B., Zischka, H., et al. (2018) · Journal of Proteome Research · doi:10.1021/acs.jproteome.8b00001 · Cited by 23

Cyclophilin D‐dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia

Veres, B., Erős, K., Antus, C., Kálmán, N., Fonai, F., Jakus, P., Boros, É., Hegedüs, Z., Nagy, I., Tretter, L., et al. (2021) · FEBS Open Bio · doi:10.1002/2211-5463.13091 · Cited by 23

Unveiling the potential of mitochondrial dynamics as a therapeutic strategy for acute kidney injury

Hao, Y., Zhao, L., Zhao, J. Y., Han, X., & Zhou, X. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1244313 · Cited by 23

ZLN005 alleviates PBDE-47 induced impairment of mitochondrial translation and neurotoxicity through PGC-1α/ERRα axis

Tian, Z., Li, J., Tang, H., Liu, W., Hou, H., Wang, C., Li, D., Chen, G., Xia, T., & Wang, A. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.134331 · Cited by 22

Cadmium and polyvinyl chloride microplastics induce mitochondrial damage and apoptosis under oxidative stress in duck kidney

Zou, H., Jie, S., Luo, X., Ali, W., Li, S., Xiong, L., Chen, Y., Yuan, Y., Ma, Y., Tong, X., et al. (2024) · Poultry Science · doi:10.1016/j.psj.2024.104490 · Cited by 22

Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways That Regulate Cardiac Metabolism and Cell Fate in Newborn Rat Hearts

Preston, C. C., Larsen, T. D., Eclov, J. A., Louwagie, E. J., Gandy, T. C. T., Faustino, R. S., & Baack, M. L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.570846 · Cited by 22

Novel Therapeutic Approaches Enhance PGC1-alpha to Reduce Oxidant Stress-Inflammatory Signaling and Improve Functional Recovery in Hibernating Myocardium

Aggarwal, R., Potel, K. N., McFalls, E. O., Butterick, T. A., & Kelly, R. F. (2022) · Antioxidants · doi:10.3390/antiox11112155 · Cited by 23

Mitochondrial Dysfunction in the Cardio-Renal Axis

Méndez‐Barbero, N., Oller, J., Sanz, A. B., Ramos, A. M., Ortíz, A., Ruiz‐Ortega, M., & Rayego‐Mateos, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098209 · Cited by 26

Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy

Ahola, S., Pazurek, L. A., Mayer, F. C., Lampe, P., Hermans, S., Becker, L., Amarie, O. V., Fuchs, H., Gailus‐Durner, V., de Angelis, M. H., et al. (2024) · Science Advances · doi:10.1126/sciadv.adp0443 · Cited by 21

3D models of dilated cardiomyopathy: Shaping the chemical, physical and topographical properties of biomaterials to mimic the cardiac extracellular matrix

Camman, M., Joanne, P., Agbulut, O., & Hélary, C. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.05.040 · Cited by 24

Bioenergetics of the aging heart and skeletal muscles: Modern concepts and controversies

Tepp, K., Timohhina, N., Puurand, M., Klepinin, A., Chekulayev, V., Shevchuk, I., & Kaambre, T. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.04.001 · Cited by 21

Excessively Enlarged Mitochondria in the Kidneys of Diabetic Nephropathy

Kim, K., & Lee, E. Y. (2021) · Antioxidants · doi:10.3390/antiox10050741 · Cited by 23

Cardiomyocyte maturation and its reversal during cardiac regeneration

Beisaw, A., & Wu, C. C. (2022) · Developmental Dynamics · doi:10.1002/dvdy.557 · Cited by 21

The in vivo drug delivery pattern of the organelle-targeting small molecules

Fang, Z., & Chen, H. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115020 · Cited by 21

Mitophagy and iron: two actors sharing the stage in age-associated neuronal pathologies

Schiavi, A., Strappazzon, F., & Ventura, N. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111252 · Cited by 22

The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise

Nijholt, K. T., Meems, L. M. G., Ruifrok, W.-P. T., Maass, A. H., Yurista, S. R., Pávez, M., Mahmoud, B., Wolters, A. H. G., van Veldhuisen, D. J., van Gilst, W. H., et al. (2021) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-021-02577-4 · Cited by 25

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

Barriales, D., Martín‐Ruiz, I., Carreras‐González, A., Montesinos-Robledo, M., Azkargorta, M., Iloro, I., Escobés, I., Martín-Mateos, T., Atondo, E., Palacios, A., et al. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001062 · Cited by 20

Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate

Fagg, W. S., Liu, N., Braunschweig, U., de Castro, K. L. P., Chen, X., Ditmars, F. S., Widen, S. G., Donohue, J. P., Módis, K., Russell, W. K., et al. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac327 · Cited by 21

Role of mitophagy in the hallmarks of aging

Wen, J., Pan, T., Li, H., Fan, H., Liu, J., Cai, Z., & Zhao, B. (2022) · Journal of Biomedical Research · doi:10.7555/jbr.36.20220045 · Cited by 20

Effect of exercise training on cardiac mitochondrial respiration, biogenesis, dynamics, and mitophagy in ischemic heart disease

Viloria, M. A. D., Li, Q., Lu, W., Nhu, N. T., Liu, Y., Cui, Z.-Y., Cheng, Y., & Lee, S. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.949744 · Cited by 20

Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function

Li, K., Wan, B., Li, S., Chen, Z., Jia, H., Song, Y., Zhang, J., Ju, W., Ma, H., & Wang, Y. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1063556 · Cited by 21

Age and Sex Influence Mitochondria and Cardiac Health in Offspring Exposed to Maternal Glucolipotoxicity

Louwagie, E. J., Larsen, T. D., Wachal, A. L., Gandy, T. C. T., Eclov, J. A., Rideout, T. C., Kern, K. A., Cain, J. T., Anderson, R. H., Mdaki, K. S., et al. (2020) · iScience · doi:10.1016/j.isci.2020.101746 · Cited by 20

Effects of nutrient restriction and arginine treatment on oxidative stress in the ovarian tissue of ewes during the luteal phase

Guo, Y., Nie, H., Xu, C., Zhang, G., Sun, L., Zhang, T., Wang, Z., Xu, F., You, P., & Wang, F. (2018) · Theriogenology · doi:10.1016/j.theriogenology.2018.02.016 · Cited by 22

Therapeutic approaches to diabetic cardiomyopathy: Targeting the antioxidant pathway

Arad, M., Waldman, M., Abraham, N. G., & Hochhauser, E. (2020) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2020.106454 · Cited by 20

Inhibiting mitochondrial excessive fission alleviates the neuronal damage in Parkinson's disease via regulating PGC-1α mediated mitochondrial biogenesis

Ma, J., Yang, Y., Zang, C., Chen, Q., Jiang, Y., Dong, Y., Wang, J., Zhou, N., Yang, X., Li, F., et al. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115288 · Cited by 18

Hypertrophic Cardiomyopathy in Infants from the Perspective of Cardiomyocyte Maturation

Seok, H., & Oh, J.-H. (2021) · Korean Circulation Journal · doi:10.4070/kcj.2021.0153 · Cited by 18

Energy metabolism homeostasis in cardiovascular diseases.

Wang, L.-Y., & Chen, C. (2021) · PubMed Central · doi:10.11909/j.issn.1671-5411.2021.12.006 · Cited by 18

Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement

Zheng, P., Zhang, Q., Ma, W., Hu, R., Gu, Y., Bian, Z., Yang, D., Chen, X., & Wu, H. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176085 · Cited by 18

Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues

Ng, R., Sewanan, L. R., Brill, A. L., Stankey, P. P., Li, X., Qyang, Y., Ehrlich, B. E., & Campbell, S. G. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00055.2020 · Cited by 18

Reclaiming Warburg: using developmental biology to gain insight into human metabolic diseases

Drummond‐Barbosa, D., & Tennessen, J. M. (2020) · Development · doi:10.1242/dev.189340 · Cited by 17

Mitochondrial division inhibitor 1 (mdivi‐1) increases oxidative capacity and contractile stress generated by engineered skeletal muscle

Rexius‐Hall, M. L., Khalil, N. N., Andres, A. M., & McCain, M. L. (2020) · The FASEB Journal · doi:10.1096/fj.201901039rr · Cited by 18

Accelerated FASTK mRNA degradation induced by oxidative stress is responsible for the destroyed myocardial mitochondrial gene expression and respiratory function in alcoholic cardiomyopathy

Zhang, F., Wang, K., Zhang, S., Li, J., Fan, R., Chen, X., & Pei, J. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101778 · Cited by 18

Chronic hypoxia alters cardiac mitochondrial complex protein expression and activity in fetal guinea pigs in a sex-selective manner

Song, H., Polster, B. M., & Thompson, L. P. (2021) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00004.2021 · Cited by 18

Comparative transcriptomic and metabolomic analysis reveals pectoralis highland adaptation across altitudinal songbirds

Xiong, Y., Yan, H. A. O., Cheng, Y., Fan, L., Song, G., Li, D., Qu, Y., & Lei, F. (2021) · Integrative Zoology · doi:10.1111/1749-4877.12620 · Cited by 18

Serum untargeted metabolomic changes in response to diet intervention in dogs with preclinical myxomatous mitral valve disease

Li, Q., Laflamme, D. P., & Bauer, J. E. (2020) · PLoS ONE · doi:10.1371/journal.pone.0234404 · Cited by 18

Mechanism and treatment of intracerebral hemorrhage focus on mitochondrial permeability transition pore

Cong, J., Li, J., & Zou, W. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1423132 · Cited by 19

The miR-27a/FOXJ3 Axis Dysregulates Mitochondrial Homeostasis in Colorectal Cancer Cells

Barisciano, G., Leo, M., Muccillo, L., Pranzini, E., Parri, M., Colantuoni, V., Taddei, M. L., & Sabatino, L. (2021) · Cancers · doi:10.3390/cancers13194994 · Cited by 18

Molecular and cellular mechanisms in diabetic heart failure: Potential therapeutic targets

Mengstie, M. A., Abebe, E. C., Teklemariam, A. B., Mulu, A. T., Teshome, A. A., Zewde, E. A., Muche, Z. T., & Azezew, M. T. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.947294 · Cited by 19

Cardiomyocyte-fibroblast crosstalk in the postnatal heart

Calderon, M. U., Gonzalez, B. A., & Yutzey, K. E. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1163331 · Cited by 19

Beyond the beat: A pioneering investigation into exercise modalities for alleviating diabetic cardiomyopathy and enhancing cardiac health

Khan, A. R., Alnoud, M. A. H., Ali, H., Ali, I., Ahmad, S., Hassan, S. S. U., Shaikh, A. L., Hussain, T., Khan, M. U., Khan, S. U., et al. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.102222 · Cited by 17

ACE2 activation alleviates sepsis-induced cardiomyopathy by promoting MasR-Sirt1-mediated mitochondrial biogenesis

Wan, T., Li, Y., Liu, L., Xiao, X., Liu, L., Li, H., & Guo, S. (2023) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2023.109855 · Cited by 17

Traditional and novel tools to probe the mitochondrial metabolism in health and disease

Zhang, Y., & Avalos‬, J. L. (2017) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1373 · Cited by 16

Mitochondrial DNA Depletion Syndrome and Its Associated Cardiac Disease

Wang, H., Han, Y., Li, S., Chen, Y., Chen, Y., Wang, J., Zhang, Y., Zhang, Y., Wang, J., Xia, Y., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.808115 · Cited by 18

Mitochondria and NLRP3 inflammasome in cardiac hypertrophy

Yan, R., Sun, Y., Yang, Y., Zhang, R., Jiang, Y., & Meng, Y. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04812-1 · Cited by 18

Mitochondrial dynamics in pulmonary disease: Implications for the potential therapeutics

Li, H., Dai, X., Zhou, J.-F., Wang, Y., Zhang, S., Guo, J., Shen, L., Yan, H., & Jiang, H. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31370 · Cited by 19

Bleomycin A5 suppresses Drp1‑mediated mitochondrial fission and induces apoptosis in human nasal polyp‑derived fibroblasts

Wu, F., Ma, Y., Wang, J., Ou, H., Dang, H., Zheng, Y., Tian, P., & Zou, H. (2020) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2020.4797 · Cited by 16

Mitogenome Analysis of Four Lamiinae Species (Coleoptera: Cerambycidae) and Gene Expression Responses by Monochamus alternatus When Infected with the Parasitic Nematode, Bursaphelenchus mucronatus

Zhang, Z.-Y., Guan, J.-Y., Cao, Y.-R., Dai, X.-Y., Storey, K. B., Yu, D., & Zhang, J. (2021) · Insects · doi:10.3390/insects12050453 · Cited by 16

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

D’Imperio, S., Monasky, M. M., Micaglio, E., Negro, G., & Pappone, C. (2021) · Nutrients · doi:10.3390/nu13082482 · Cited by 16

Malfunction in Mitochondrial β-Oxidation Contributes to Lipid Accumulation in Hepatocyte-Like Cells Derived from Citrin Deficiency-Induced Pluripotent Stem Cells

Kim, Y., Choi, J.-Y., Lee, S.-H., Lee, B. H., Yoo, H., & Han, Y. (2016) · Stem Cells and Development · doi:10.1089/scd.2015.0342 · Cited by 16

Cellular and Molecular Pathways in Diabetes-Associated Heart Failure: Emerging Mechanistic Insights and Therapeutic Opportunities

Ktenopoulos, N., Anagnostopoulou, L., Apostolos, A., Iliakis, P., Karakasis, P., Milaras, N., Theofilis, P., Fragoulis, C., Drakopoulou, M., Synetos, A. G., et al. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47110886 · Cited by 19

Hypertrophic signaling compensates for contractile and metabolic consequences of DNA methyltransferase 3A loss in human cardiomyocytes

Madsen, A., Krause, J., Höppner, G., Hirt, M. N., Tan, W. L. W., Lim, I. Y., Hansen, A., Nikolaev, V. O., Foo, R., Thomas Eschenhagen, A., et al. (2021) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2021.02.002 · Cited by 15

PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis

Tian, Z., Li, J., Li, S., Xie, L., Li, D., Xia, T., & Wang, A. (2022) · Toxicological Sciences · doi:10.1093/toxsci/kfac110 · Cited by 15

Epigallocatechin-3-gallate restores mitochondrial homeostasis impairment by inhibiting HDAC1-mediated NRF1 histone deacetylation in cardiac hypertrophy

Li, G., Pan, B., Liu, L., Xu, X., Zhao, W., Mou, Q., Hwang, N., Chung, S. W., Liu, X., & Tian, J. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04768-2 · Cited by 15

The effect of vitrification on blastocyst mitochondrial DNA dynamics and gene expression profiles

Pérez-Sánchez, M., Pardiñas, M. L., Díez‐Juan, A., Quiñonero, A., Domı́nguez, F., Martín, Á., Vidal, C., Beltrán, D., Mifsud, A., Mercader, A., et al. (2023) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-023-02952-3 · Cited by 15

A review: Polysaccharides targeting mitochondria to improve obesity

Chen, Y., Gao, R., Fang, J., & Ding, S. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134448 · Cited by 18

Diabetic Cardiomyopathy: Focus on Oxidative Stress, Mitochondrial Dysfunction and Inflammation

Nunes, S., Rolo, A. P., Palmeira, C. M., & Reis, F. (2017) · InTech eBooks · doi:10.5772/65915 · Cited by 15

An Automated Multidose Synthesis of the Potentiometric PET Probe 4-[18F]Fluorobenzyl-Triphenylphosphonium ([18F]FBnTP)

Waldmann, C. M., Gomez, A., Marchis, P. D., Bailey, S. T., Momcilovic, M., Jones, A. E., Shackelford, D. B., & Sadeghi, S. (2017) · Molecular Imaging and Biology · doi:10.1007/s11307-017-1119-1 · Cited by 15

Metabolic Reprogramming, Gut Dysbiosis, and Nutrition Intervention in Canine Heart Disease

Li, Q. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.791754 · Cited by 15

Human induced pluripotent stem cells for studying mitochondrial diseases in the heart

Caudal, A., Ren, L., Tu, C., & Wu, J. C. (2022) · FEBS Letters · doi:10.1002/1873-3468.14444 · Cited by 15

FGFR1 is essential for N-acetyl-seryl-aspartyl-lysyl-proline regulation of mitochondrial dynamics by upregulating microRNA let-7b-5p

Hu, Q., Li, J., Nitta, K., Kitada, M., Nagai, T., Kanasaki, K., & Koya, D. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.12.089 · Cited by 15

Intrauterine Programming of Cardiovascular Diseases in Maternal Diabetes

Higa, R., Leonardi, M. L., & Jawerbaum, A. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.760251 · Cited by 15

Cardio-Onco-Metabolism – Metabolic vulnerabilities in cancer and the heart

Karlstaedt, A., & Taegtmeyer, H. (2022) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2022.06.008 · Cited by 15

Potential candidates from marine and terrestrial resources targeting mitochondrial inhibition: Insights from the molecular approach

Mitra, S., Rauf, A., Sutradhar, H., Sadaf, S., Hossain, M. J., Soma, M. A., Emran, T. B., Ahmad, B., Aljohani, A. S. M., Abdulmonem, W. A., et al. (2022) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2022.109509 · Cited by 15

Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1

Zhu, H., Yan, C., Yao, P., Li, P., Li, Y., & Yang, H. Q. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.04.015 · Cited by 14

The mitochondrial link: Phthalate exposure and cardiovascular disease

Kabekkodu, S. P., Gladwell, L. R., & Choudhury, M. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2024.119708 · Cited by 15

Di-(2-ethylhexyl) Phthalate Exposure Induces Developmental Toxicity in the Mouse Fetal Heart via Mitochondrial Dysfunction

Guo, Y., Li, B., Yu, Y., Zhang, N., Shao, S., Yang, L., Ouyang, L., Wu, P., Ma, F., Duan, H., et al. (2024) · Cardiovascular Toxicology · doi:10.1007/s12012-024-09936-4 · Cited by 14

New insights into mitochondrial quality control in anthracycline-induced cardiotoxicity: molecular mechanisms, therapeutic targets, and natural products

Li, W., Zhang, Y., Yan, W., Ling, G., Zhang, Y., Li, Y., Guo, S., Tan, N., Ma, L., Li, W., et al. (2024) · International Journal of Biological Sciences · doi:10.7150/ijbs.103810 · Cited by 14

Enhanced fatty acid oxidation via SCD1 downregulation fuels cardiac reprogramming

Jia, Z., Xiang, L., Yu, Z., Wang, L., Fang, J., Liu, M., Lu, Z., Lu, Z., & Wang, L. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.02.034 · Cited by 14

Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis

Milstone, Z. J., Saheera, S., Bourke, L. M., Shpilka, T., Haynes, C. M., & Trivedi, C. M. (2020) · Science Advances · doi:10.1126/sciadv.aax5150 · Cited by 15

Mechanisms of Chronic Metabolic Stress in Arrhythmias

Gowen, B. H., Reyes, M. V., Joseph, L. C., & Morrow, J. (2020) · Antioxidants · doi:10.3390/antiox9101012 · Cited by 16

Regulation of mitochondrial dynamics in cardiomyocytes: implications for cardiac health and disease

Zhang, T., Li, Z., Xu, Y., Xu, C., Wang, H., & Tao, R. X. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1652683 · Cited by 17

EPAC1 inhibition protects the heart from doxorubicin-induced toxicity

Mazevet, M., Belhadef, A., Ribeiro, M., Daydé, D., Llach, A., Laudette, M., Belleville‐Rolland, T., Matéo, P., Gressette, M., Lefebvre, F., et al. (2023) · eLife · doi:10.7554/elife.83831 · Cited by 13

Brain Mitochondria as a Therapeutic Target for Carnosic Acid

Infantino, V., Pappalardo, I., Santarsiero, A., Tripathi, S., Singh, G., & de Oliveira, M. R. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2303053 · Cited by 13

The significance of the apelinergic system in doxorubicin-induced cardiotoxicity

Matusik, K., Kamińska, K., Sobiborowicz, A., Borzuta, H., Buczma, K., & Cudnoch‐Jędrzejewska, A. (2024) · Heart Failure Reviews · doi:10.1007/s10741-024-10414-w · Cited by 14

Maternal Metformin Treatment during Gestation and Lactation Improves Skeletal Muscle Development in Offspring of Rat Dams Fed High-Fat Diet

Cui, J., Song, L., Wang, R., Hu, S., Yang, Z., Zhang, Z., Sun, B., & Cui, W. (2021) · Nutrients · doi:10.3390/nu13103417 · Cited by 13

Protective effects of Shen Yuan Dan on myocardial ischemia-reperfusion injury via the regulation of mitochondrial quality control

Zhang, Z., Zhou, M., Liu, H., Liu, W., & Chen, J. P. (2023) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-23-86 · Cited by 12

Metabolic modulation of mitochondrial mass during CD4+ T cell activation

Kurmi, K., Liang, D., van de Ven, R., Georgiev, P., Gassaway, B. M., Han, S., Notarangelo, G., Harris, I. S., Yao, C.-H., Park, J. S., et al. (2023) · Cell chemical biology · doi:10.1016/j.chembiol.2023.08.008 · Cited by 12

Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model

Pereira, S. P., Diniz, M. S., Tavares, L. C., Cunha‐Oliveira, T., Li, C., Cox, L. A., Nijland, M. J., Nathanielsz, P. W., & Oliveira, P. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015192 · Cited by 12

Pyruvate kinase M2 sustains cardiac mitochondrial integrity in septic cardiomyopathy by regulating PHB2-dependent mitochondrial biogenesis

Ren, J., Ren, B., Fu, T., Ma, Y., Tan, Y., Zhang, S., Li, Y., Wang, Q., Chang, X., & Tong, Y. (2024) · International Journal of Medical Sciences · doi:10.7150/ijms.94577 · Cited by 12

The application and prospects of drug delivery systems in idiopathic pulmonary fibrosis

Zhang, X., Zhang, L., Tian, J.-H., Li, Y., Wu, M., Zhang, L., Qin, X., & Gong, L. (2024) · Biomaterials Advances · doi:10.1016/j.bioadv.2024.214123 · Cited by 13

The Impact of Obesity on Cardiac Energy Metabolism and Efficiency in Heart Failure With Preserved Ejection Fraction

Ketema, E. B., & Lopaschuk, G. D. (2025) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2025.01.029 · Cited by 14

Targeting Mitochondrial Metabolism to Save the Failing Heart

Schenkl, C., Heyne, E., Doenst, T., Schulze, P. C., & Nguyễn, T. D. (2023) · Life · doi:10.3390/life13041027 · Cited by 12

Cardiac mitochondrial dynamics: miR-mediated regulation during cardiac injury

Sivakumar, A., Subbiah, R., Balakrishnan, R., & Rajendhran, J. (2017) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2017.07.003 · Cited by 13

Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration

Wen, S., Unuma, K., Funakoshi, T., Aki, T., & Uemura, K. (2021) · Scientific Reports · doi:10.1038/s41598-021-03631-y · Cited by 12

Piperine Derivatives Enhance Fusion and Axonal Transport of Mitochondria by Activating Mitofusins

Zhang, L., Dang, X., Franco, A., Zhao, H., & Dorn, G. W. (2022) · Chemistry · doi:10.3390/chemistry4030047 · Cited by 12

Bisphenol-A Mediated Impaired DRP1-GFER Axis and Cognition Restored by PGC-1α Upregulation Through Nicotinamide in the Rat Brain Hippocampus

Goyal, S., Tiwari, S., Seth, B., Phoolmala, Tandon, A., & Chaturvedi, R. K. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02862-y · Cited by 11

SETD3 is a mechanosensitive enzyme that methylates actin on His73 to regulate mitochondrial dynamics and function

Deshmukh, V., & Martin, J. F. (2024) · Journal of Cell Science · doi:10.1242/jcs.261268 · Cited by 11

Myocardium-specific Isca1 knockout causes iron metabolism disorder and myocardial oncosis in rat

Ling, Y., Yang, X., Zhang, X., Guan, F., Qi, X., Dong, W., Liu, M., Ma, J., Jiang, X., Gao, K., et al. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120485 · Cited by 11

Ginsenoside Rb3 upregulates sarcoplasmic reticulum Ca2+-ATPase expression and improves the contractility of cardiomyocytes by inhibiting the NF-κB pathway

Shao, M., Gao, P., Cheng, W., Ma, L., Ye, Y., Lu, L., Li, C., Wang, W., & Wang, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113661 · Cited by 11

Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy

Ricci, C. A., Reid, D. M., Sun, J. L., Santillan, D. A., Santillan, M. K., Phillips, N., & Goulopoulou, S. (2023) · Physiological Genomics · doi:10.1152/physiolgenomics.00005.2023 · Cited by 11

Further investigation of mitochondrial biogenesis and gene expression of key regulators in ascites- susceptible and ascites- resistant broiler research lines

Alzahrani, K., Licknack, T. J., Watson, D. L., Anthony, N. B., & Rhoads, D. D. (2019) · PLoS ONE · doi:10.1371/journal.pone.0205480 · Cited by 12

Cancer Stem-Like Phenotype of Mitochondria Dysfunctional Hep3B Hepatocellular Carcinoma Cell Line

Han, Y.-S., Yi, E.-Y., Jegal, M.-E., & Kim, Y.-J. (2021) · Cells · doi:10.3390/cells10071608 · Cited by 11

Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells

Pávez, M., & Cyganek, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.800529 · Cited by 12

Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity

Lau, W. K., Noruddin, N. A. A., Ariffin, A. H., Mahmud, M. Z., Noor, M. H. M., Amanah, A., Hamzah, M. F., & Zainuddin, Z. (2019) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-019-2640-3 · Cited by 11

Role of SIRT1 in Potentially Toxic Trace Elements (Lead, Fluoride, Aluminum and Cadmium) Associated Neurodevelopmental Toxicity

Fathima, A., Bagang, N., Kumar, N., Dastidar, S. G., & Shenoy, S. (2024) · Biological Trace Element Research · doi:10.1007/s12011-024-04116-5 · Cited by 12

Maintaining Ancient Organelles

Vega, R. B., Horton, J. L., & Kelly, D. P. (2015) · Circulation Research · doi:10.1161/circresaha.116.305420 · Cited by 147

Regulation of mitochondrial biogenesis and energy metabolism in the heart

She, P., 莫非, Zhu, P., & Zhong, T. P. (2026) · Chinese Medical Journal · doi:10.1097/cm9.0000000000004011 · Cited by 2

A change of heart (mitochondria)

Hurtley, S. M. (2015) · Science Signaling · doi:10.1126/scisignal.aad9940 · Cited by 1

Transcriptional Control of Striated Muscle Mitochondrial Biogenesis and Function

Kelly, D. P., & Scarpulla, R. C. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-381510-1.00016-8 · Cited by 4

Mitochondrial Function during and Regulation of Cardiac Development

Porter, G. A., Jr. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2015.11.044