Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,240 · see citing works

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Chomczyński, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90021-2 · Cited by 47,092 · see citing works

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956 · see citing works

Altering the Genome by Homologous Recombination

Capecchi, M. R. (1989) · Science · doi:10.1126/science.2660260 · Cited by 2,037 · see citing works

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

Doetschman, T., Eistetter, H. R., Katz, M., Schmidt, W., & Kemler, R. (1985) · Development · doi:10.1242/dev.87.1.27 · Cited by 1,962 · see citing works

Position-independent, high-level expression of the human β-globin gene in transgenic mice

Grosveld, F. G., van Assendelft, G. B., Greaves, D. R., & Kollias, G. A. (1987) · Cell · doi:10.1016/0092-8674(87)90584-8 · Cited by 1,908 · see citing works

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

Hasty, P., Bradley, A., Morris, J. H., Edmondson, D. G., Venuti, J. M., Olson, E. N., & Klein, W. H. (1993) · Nature · doi:10.1038/364501a0 · Cited by 1,364 · see citing works

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

Pevny, L., Simon, M. C., Robertson, E., Klein, W. H., Tsai, S.-F., D'Agati, V., Orkin, S. H., & Costantini, F. (1991) · Nature · doi:10.1038/349257a0 · Cited by 1,308 · see citing works

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

Mucenski, M. L., McLain, K., Kier, A. B., Swerdlow, S. H., Schreiner, C. M., Miller, T. A., Pietryga, D. W., Scott, W. J., & Potter, S. S. (1991) · Cell · doi:10.1016/0092-8674(91)90099-k · Cited by 1,041 · see citing works

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

Rudnicki, M. A., Braun, T. W., Hinuma, S., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90508-a · Cited by 984 · see citing works

Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination

Smithies, O., Gregg, R. G., Boggs, S. S., Koralewski, M. A., & Kucherlapati, R. (1985) · Nature · doi:10.1038/317230a0 · Cited by 977 · see citing works

Myogenin gene disruption results in perinatal lethality because of severe muscle defect

Nabeshima, Y., Hanaoka, K., Hayasaka, M., Esuml, E., Li, S., Nonaka, I., & Nabeshima, Y.-I. (1993) · Nature · doi:10.1038/364532a0 · Cited by 954 · see citing works

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

Tsai, S., Martin, D. I. K., Zon, L. I., D’Andrea, A. D., Wong, G. G., & Orkin, S. H. (1989) · Nature · doi:10.1038/339446a0 · Cited by 884 · see citing works

GATA-binding transcription factors in hematopoietic cells

Orkin, S. (1992) · Blood · doi:10.1182/blood.v80.3.575.575 · Cited by 884 · see citing works

Hematopoietic Commitment During Embryonic Stem Cell Differentiation in Culture

Keller, G. M., Kennedy, M. A., Papayannopoulou, T., & Wiles, M. V. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.1.473 · Cited by 881 · see citing works

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

Robertson, E. J., Bradley, A., Kuehn, M. R., & Evans, M. J. (1986) · Nature · doi:10.1038/323445a0 · Cited by 751 · see citing works

Expression cloning of the murine erythropoietin receptor

D’Andrea, A. D., Lodish, H. F., & Wong, G. G. (1989) · Cell · doi:10.1016/0092-8674(89)90965-3 · Cited by 737 · see citing works

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

Miller, I. J., & Bieker, J. J. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.5.2776-2786.1993 · Cited by 725 · see citing works

DNA-Binding Specificity of GATA Family Transcription Factors

Merika, M., & Orkin, S. H. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.7.3999-4010.1993 · Cited by 671 · see citing works

Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies

Risau, W., Sariola, H. V., Zerwes, H., Sasse, J., Ekblom, P., Kemler, R., & Doetschman, T. (1988) · Development · doi:10.1242/dev.102.3.471 · Cited by 656 · see citing works

Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates

Alonso, S., Minty, A. J., Bourlet, Y., & BUCKINGHAM, M. E. (1986) · Journal of Molecular Evolution · doi:10.1007/bf02100994 · Cited by 643 · see citing works

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.Preprint

Yamamoto, M. P., Ko, L. J., Leonard, M. W., Beug, H., Orkin, S. H., & Engel, J. D. (1990) · Genes & Development · doi:10.1101/gad.4.10.1650 · Cited by 598 · see citing works

Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture

Wiles, M. V., & Keller, G. M. (1991) · Development · doi:10.1242/dev.111.2.259 · Cited by 597 · see citing works

The erythroid-specific transcription factor eryf1: A new finger protein

Evans, T., & Felsenfeld, G. (1989) · Cell · doi:10.1016/0092-8674(89)90940-9 · Cited by 580 · see citing works

DNA-Binding Specificities of the GATA Transcription Factor Family

Ko, L. J., & Engel, J. D. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.7.4011-4022.1993 · Cited by 575 · see citing works

An early pre-liver intraembryonic source of CFU-S in the developing mouse

Medvinskiĭ, A. L., Samoylina, N. L., Müller, A. M., & Dzierzak, E. A. (1993) · Nature · doi:10.1038/364064a0 · Cited by 507 · see citing works

An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

Evans, T., Reitman, M. L., & Felsenfeld, G. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.16.5976 · Cited by 485 · see citing works

New light on Myc and Myb. Part II. Myb.Preprint

Lüscher, B., & Eisenman, R. N. (1990) · Genes & Development · doi:10.1101/gad.4.12b.2235 · Cited by 475 · see citing works

Globin gene regulation and switching: Circa 1990

Orkin, S. H. (1990) · Cell · doi:10.1016/0092-8674(90)90133-y · Cited by 462 · see citing works

Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages

Martin, D. I. K., Zon, L. I., Mutter, G. L., & Orkin, S. H. (1990) · Nature · doi:10.1038/344444a0 · Cited by 455 · see citing works

A c- myb Antisense Oligodeoxynucleotide Inhibits Normal Human Hematopoiesis in Vitro

Gewirtz, A. M., & Calabretta, B. (1988) · Science · doi:10.1126/science.2461588 · Cited by 424 · see citing works

Megakaryocytic and erythrocytic lineages share specific transcription factors

Roméo, P., Prandini, M., Joulin, V., Mignotte, V., Prenant, M., Vainchenker, W., Marguerie, G., & Uzan, G. (1990) · Nature · doi:10.1038/344447a0 · Cited by 417 · see citing works

The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites

Konkel, D. A., Tilghman, S. M., & Leder, P. (1978) · Cell · doi:10.1016/0092-8674(78)90040-5 · Cited by 406 · see citing works

Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors

Godin, I., García‐Porrero, J. A., Coutinho, A., Dieterlen‐Lièvre, F., & Marcos, M. A. R. (1993) · Nature · doi:10.1038/364067a0 · Cited by 387 · see citing works

Quantitative or semi-quantitative PCR: reality versus myth.Preprint

Ferre, F. (1992) · Genome Research · doi:10.1101/gr.2.1.1 · Cited by 351 · see citing works

Human GATA‐3: a lineage‐restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

Ho, I., Vorhees, P., Marín, N., Oakley, B. K., Tsai, S., Orkin, S. H., & Leiden, J. M. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb08059.x · Cited by 349 · see citing works

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.

Begley, C. G., Aplan, P. D., Denning, S. M., Haynes, B. F., Waldmann, T. A., & Kirsch, I. R. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.10128 · Cited by 346 · see citing works

A major positive regulatory region located far upstream of the human alpha-globin gene locus.Preprint

Higgs, D. R., Wood, W. G., Jarman, A. P., Sharpe, J. A., Lida, J., Pretorius, I., & Ayyub, H. (1990) · Genes & Development · doi:10.1101/gad.4.9.1588 · Cited by 335 · see citing works

Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression.Preprint

Schmitt, R., Bruyns, E., & Snodgrass, H. R. (1991) · Genes & Development · doi:10.1101/gad.5.5.728 · Cited by 332 · see citing works

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

Nishioka, Y., & Leder, P. (1979) · Cell · doi:10.1016/0092-8674(79)90139-9 · Cited by 315 · see citing works

Detailed analysis of the site 3 region of the human beta‐globin dominant control region.

Talbot, D., Philipsen, S., Fraser, P., & Grosveld, F. G. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07386.x · Cited by 311 · see citing works

Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation.

Clarke, M. F., Kukowska‐Latallo, J. F., Westin, E. H., Smith, M. J., & Prochownik, E. V. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.2.884 · Cited by 299 · see citing works

Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer.

Ko, L. J., Yamamoto, M. P., Leonard, M. W., George, K. M., Ting, P., & Engel, J. D. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.5.2778 · Cited by 293 · see citing works

Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.

Dorfman, D. M., Wilson, D. B., Bruns, G. A. P., & Orkin, S. H. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48426-8 · Cited by 281 · see citing works

The beta‐globin dominant control region: hypersensitive site 2.

Philipsen, S., Talbot, D., Fraser, P., & Grosveld, F. G. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07385.x · Cited by 281 · see citing works

Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants

Konecki, D. S., Brennand, J. C., Fuscoe, J. C., Caskey, C. T., & Chinault, A. C. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.21.6763 · Cited by 275 · see citing works

Increased γ-globin expression in a nondeletion HPFH mediated by an erythroid-specif ic DNA-binding factor

Martin, D. I. K., Tsai, S., & Orkin, S. H. (1989) · Nature · doi:10.1038/338435a0 · Cited by 274 · see citing works

Rescue of erythroid development in gene targeted GATA–1− mouse embryonic stem cells

Simon, M. C., Pevny, L., Wiles, M. V., Keller, G. M., Costantini, F. D., & Orkin, S. H. (1992) · Nature Genetics · doi:10.1038/ng0592-92 · Cited by 248 · see citing works

Dynamics of GATA transcription factor expression during erythroid differentiation

Leonard, M. O., Brice, M. C., Engel, J., & Papayannopoulou, T. (1993) · Blood · doi:10.1182/blood.v82.4.1071.1071 · Cited by 238 · see citing works

Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development

Wang, R., Clark, R., & Bautch, V. L. (1992) · Development · doi:10.1242/dev.114.2.303 · Cited by 234 · see citing works

The SCL gene product: a positive regulator of erythroid differentiation.

Aplan, P. D., Nakahara, K., Orkin, S. H., & Kirsch, I. R. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05500.x · Cited by 230 · see citing works

The 5′HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF‐E2 binding sites.

Talbot, D., & Grosveld, F. G. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07659.x · Cited by 226 · see citing works

Activation of the erythropoietin receptor promoter by transcription factor GATA-1.

Zon, L. I., Youssoufian, H., Mather, C., Lodish, H. F., & Orkin, S. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.23.10638 · Cited by 221 · see citing works

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.Preprint

Briegel, K. J., Lim, K. C., Plank, C., Beug, H., Engel, J. D., & Zenke, M. (1993) · Genes & Development · doi:10.1101/gad.7.6.1097 · Cited by 208 · see citing works

Expression and function of CD4 in a murine T-cell hybridoma

Sleckman, B. P., Peterson, A. S., Jones, W. K., Foran, J. A., Greenstein, J. L., Seed, B., & Burakoff, S. J. (1987) · Nature · doi:10.1038/328351a0 · Cited by 200 · see citing works

Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation.

Todokoro, K., Watson, R. J., Higo, H., Amanuma, H., Kuramochi, S., Yanagisawa, H., & Ikawa, Y. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.23.8900 · Cited by 176 · see citing works

A T‐cell specific TCR delta DNA binding protein is a member of the human GATA family.

Joulin, V., Bories, D., Eléouët, J., Labastie, M.-C., Chrétien, S., Mattéi, M., & Roméo, P. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07706.x · Cited by 172 · see citing works

Characterization of the Major Regulatory Element Upstream of the Human a-Globin Gene Cluster

Jarman, A. P., Wood, W. G., Sharpe, J. A., Gourdon, G., Ayyub, H., & Higgs, D. R. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.9.4679-4689.1991 · Cited by 171 · see citing works

In vitro chamber specification during embryonic stem cell cardiogenesis. Expression of the ventricular myosin light chain-2 gene is independent of heart tube formation.

Miller‐Hance, W. C., LaCorbiere, M., Fuller, S. J., Evans, S. Μ., Lyons, G. E., Schmidt, C., Robbins, J. M., & Chien, K. R. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74594-3 · Cited by 170 · see citing works

Hemoglobin ontogeny during normal mouse fetal development.

Brotherton, T. W., Chui, D. H. K., Gauldie, J., & Patterson, M. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.6.2853 · Cited by 170 · see citing works

A Nonerythroid GATA-Binding Protein Is Required for Function of the Human Preproendothelin-1 Promoter in Endothelial Cells

Wilson, D. B., Dorfman, D. M., & Orkin, S. H. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.9.4854-4862.1990 · Cited by 167 · see citing works

Expression of GATA-binding proteins during embryonic development in Xenopus laevis.

Zon, L. I., Mather, C., Burgess, S., Bolce, M. E., Harland, R. M., & Orkin, S. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.23.10642 · Cited by 166 · see citing works

Regulated Expression of Globin Chains and the Erythroid Transcription Factor GATA-1 during Erythropoiesis in the Developing Mouse

Whitelaw, E., Tsai, S., Hogben, P., & Orkin, S. H. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.12.6596-6606.1990 · Cited by 163 · see citing works

Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.

Jiménez, G., Griffiths, S. D., Ford, A. M., Greaves, M. F., & Enver, T. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.10618 · Cited by 157 · see citing works

GATAAG; acis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression

Plumb, M., Frampton, J., Wainwright, H., Walker, M., Macleod, K. F., Goodwin, G. H., & Harrison, P. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.1.73 · Cited by 143 · see citing works

Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors.

Sposi, N. M., Zon, L. I., Carè, A., Valtieri, M., Testa, U., Gabbianelli, M., Mariani, G., Bottero, L., Mather, C., & Orkin, S. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.14.6353 · Cited by 142 · see citing works

Death-defying acts: a meeting review on apoptosis.Preprint

White, E. (1993) · Genes & Development · doi:10.1101/gad.7.12a.2277 · Cited by 128 · see citing works

Developmental Analysis of Tropomyosin Gene Expression in Embryonic Stem Cells and Mouse Embryos

Muthuchamy, M., Pajak, L., Howles, P. N., Doetschman, T., & Wieczorek, D. F. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3311 · Cited by 126 · see citing works

Synthetic human beta‐globin 5′HS2 constructs function as locus control regions only in multicopy transgene concatamers.

Ellis, J., Talbot, D., Dillon, N., & Grosveld, F. G. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05638.x · Cited by 121 · see citing works

The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region.

Philipsen, S., Pruzina, S., & Grosveld, F. G. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05749.x · Cited by 99 · see citing works

Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene.

Mcclinton, D., Stafford, J., Brents, L. A., Bender, T. P., & Kuehl, W. M. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.2.705 · Cited by 96 · see citing works

Early fetal hematopoietic development from in vitro differentiated embryonic stem cells.

Burkert, U., von Rüden, T., & Wagner, E. F. (1991) · PubMed · Cited by 94 · see citing works

trans-Activation of a globin promoter in nonerythroid cells.

Evans, T., & Felsenfeld, G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.2.843 · Cited by 92 · see citing works

The erythroid-specific protein cGATA-1 mediates distal enhancer activity through a specialized beta-globin TATA box.Preprint

Fong, T. C., & Emerson, B. (1992) · Genes & Development · doi:10.1101/gad.6.4.521 · Cited by 82 · see citing works

Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL.

Begley, C. G., Visvader, J. E., Green, A. R., Aplan, P. D., Metcalf, D., Kirsch, I. R., & Gough, N. M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.3.869 · Cited by 76 · see citing works

Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.

Hill, A., Hardies, S. C., Phillips, S. J., Davis, M. G., Hutchison, C. A., & Edgell, M. H. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43157-7 · Cited by 69 · see citing works

Structural organization and nucleotide sequence of mouse c-myboncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5′ coding sequences

Lavu, S., & Reddy, E. P. (1986) · Nucleic Acids Research · doi:10.1093/nar/14.13.5309 · Cited by 59 · see citing works

Identification and characterization of a chicken alpha-globin enhancer.

Knezetic, J. A., & Felsenfeld, G. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.3.893 · Cited by 54 · see citing works

In situ hybridization reveals co-expression of embryonic and adult α globin genes in the earliest murine erythrocyte progenitors

Leder, A., Kuo, A., Shen, M. M., & Leder, P. (1992) · Development · doi:10.1242/dev.116.4.1041 · Cited by 52 · see citing works

The sequence of a mouse embryonic beta-globin gene. Evolution of the gene and its signal region.

HANSEN, J. N., Konkel, D. A., & Leder, P. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)68306-7 · Cited by 51 · see citing works

A factor binding GATAAG confers tissue specificity on the promoter of the humanζ-globin gene

Watt, P. M., Lamb, P., Squire, L., & Proudfoot, N. J. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.6.1339 · Cited by 48 · see citing works

Characterization, Expression, and Evolution of the Mouse Embryonic ζ-Globin Gene

Leder, A., Weir, L., & Leder, P. (1985) · Molecular and Cellular Biology · doi:10.1128/mcb.5.5.1025-1033.1985 · Cited by 42 · see citing works

Erythropoietin triggers a burst of GATA-1 in normal human erythroid cells differentiating in tissue culture

Dalyot-Herman, N., Fibach, E., Ronchi, A. E., Rachmilewitz, E. A., Ottolenghi, S., & Oppenheim, A. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.17.4031 · Cited by 29 · see citing works

Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression

Snodgrass, H. R., Bruyns, E., & SCHMITT, R. (2021) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/zjcs-ew77 · Cited by 21 · see citing works

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L., & Schuh, A. C. (1995) · Nature · doi:10.1038/376062a0 · Cited by 3,931 · see citing works

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617 · see citing works

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G., & Downing, J. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80986-1 · Cited by 1,856 · see citing works

An early haematopoietic defect in mice lacking the transcription factor GATA-2

Tsai, F., Keller, G. M., Kuo, F. C., Weiss, M. J., Chen, J., Rosenblatt, M., Alt, F. W., & Orkin, S. H. (1994) · Nature · doi:10.1038/371221a0 · Cited by 1,419 · see citing works

Embryonic stem cell differentiation: emergence of a new era in biology and medicinePreprint

Keller, G. M. (2005) · Genes & Development · doi:10.1101/gad.1303605 · Cited by 1,144 · see citing works

Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse

Palis, J., Robertson, S. M., Kennedy, M., Wall, C., & Keller, G. M. (1999) · Development · doi:10.1242/dev.126.22.5073 · Cited by 1,050 · see citing works

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.Preprint

Kuo, C. T., Morrisey, E. E., Anandappa, R. T., Sigrist, K. S., Lu, M. M., Parmacek, M. S., Soudais, C., & Leiden, J. M. (1997) · Genes & Development · doi:10.1101/gad.11.8.1048 · Cited by 1,039 · see citing works

In vitro differentiation of embryonic stem cells

Keller, G. M. (1995) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(95)80071-9 · Cited by 953 · see citing works

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Shivdasani, R. A., Mayer, E. L., & Orkin, S. H. (1995) · Nature · doi:10.1038/373432a0 · Cited by 938 · see citing works

The LIM‐only protein Lmo2 is a bridging molecule assembling an erythroid, DNA‐binding complex which includes the TAL1, E47, GATA‐1 and Ldb1/NLI proteins

Wadman, I., Osada, H., Grütz, G. G., Agulnick, A. D., Westphal, H., Forster, A., & Rabbitts, T. H. (1997) · The EMBO Journal · doi:10.1093/emboj/16.11.3145 · Cited by 836 · see citing works

Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants

Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., & Zon, L. I. (2003) · Nature Immunology · doi:10.1038/ni1007 · Cited by 800 · see citing works

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

Fujiwara, Y., Browne, C. P., Cunniff, K., Goff, S. C., & Orkin, S. H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12355 · Cited by 778 · see citing works

The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages

Porcher, C., Swat, W., Rockwell, K. R., Fujiwara, Y., Alt, F. W., & Orkin, S. H. (1996) · Cell · doi:10.1016/s0092-8674(00)80076-8 · Cited by 731 · see citing works

A lineage‐selective knockout establishes the critical role of transcription factor GATA‐1 in megakaryocyte growth and platelet development

Shivdasani, R. A., Fujiwara, Y., McDevitt, M. A., & Orkin, S. H. (1997) · The EMBO Journal · doi:10.1093/emboj/16.13.3965 · Cited by 671 · see citing works

The cardiac transcription factors Nkx2‐5 and GATA‐4 are mutual cofactors

Durocher, D., Charron, F., Warren, R., Schwartz, R. J., & Nemer, M. J. (1997) · The EMBO Journal · doi:10.1093/emboj/16.18.5687 · Cited by 668 · see citing works

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

Parkins, A. C., Sharpe, A. H., & Orkin, S. H. (1995) · Nature · doi:10.1038/375318a0 · Cited by 599 · see citing works

Transcription Factor GATA-2 Is Required for Proliferation/Survival of Early Hematopoietic Cells and Mast Cell Formation, But Not for Erythroid and Myeloid Terminal Differentiation

Tsai, F., & Orkin, S. H. (1997) · Blood · doi:10.1182/blood.v89.10.3636.3636_3636_3643 · Cited by 601 · see citing works

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

Robb, L., Lyons, I., Li, R., Hartley, L., Köntgen, F., Harvey, R. P., Metcalf, D., & Begley, C. G. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.15.7075 · Cited by 577 · see citing works

Lymphoid Potential, Probed before Circulation in Mouse, Is Restricted to Caudal Intraembryonic Splanchnopleura

Cumano, A., Dieterlen‐Lièvre, F., & Godin, I. (1996) · Cell · doi:10.1016/s0092-8674(00)80166-x · Cited by 567 · see citing works

The transcriptional control of hematopoiesis [see comments]

Shivdasani, R., & Orkin, S. (1996) · Blood · doi:10.1182/blood.v87.10.4025.bloodjournal87104025 · Cited by 560 · see citing works

Three-dimensional cell cultures: from molecular mechanisms to clinical applications

Mueller‐Klieser, W. (1997) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1997.273.4.c1109 · Cited by 537 · see citing works

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

Nichols, K. E., Crispino, J. D., Poncz, M., White, J. G., Orkin, S. H., Maris, J. M., & Weiss, M. J. (2000) · Nature Genetics · doi:10.1038/73480 · Cited by 511 · see citing works

Erythroblastic islands: niches for erythropoiesis

Chasis, J. A., & Mohandas, N. (2008) · Blood · doi:10.1182/blood-2008-03-077883 · Cited by 506 · see citing works

Disruption of the mouse RBP-J к gene results in early embryonic death

Oka, C., Nakano, T., Wakeham, A. C., de la Pompa, J. L., Mori, C., Sakai, T., Okazaki, S., Kawaichi, M., Shiota, K., Mak, T. W., et al. (1995) · Development · doi:10.1242/dev.121.10.3291 · Cited by 477 · see citing works

The transcription factor GATA6 is essential for early extraembryonic development

Koutsourakis, M., Langeveld, A., Patient, R. K., Beddington, R. S. P., & Grosveld, F. G. (1999) · Development · doi:10.1242/dev.126.4.723 · Cited by 454 · see citing works

GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis

Ferreira, R., Ohneda, K., Yamamoto, M. P., & Philipsen, S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.4.1215-1227.2005 · Cited by 442 · see citing works

Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis.Preprint

Lin, C. S., Lim, S. K., D’Agati, V. D., & Costantini, F. D. (1996) · Genes & Development · doi:10.1101/gad.10.2.154 · Cited by 419 · see citing works

GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts.

Kulessa, H., Frampton, J., & Graf, T. (1995) · Genes & Development · doi:10.1101/gad.9.10.1250 · Cited by 418 · see citing works

Global regulation of erythroid gene expression by transcription factor GATA-1

Welch, J. J. (2004) · Blood · doi:10.1182/blood-2004-04-1603 · Cited by 411 · see citing works

Profile of Histone Lysine Methylation across Transcribed Mammalian Chromatin

Vakoc, C. R., Sachdeva, M. M., Wang, H., & Blobel, G. A. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01529-06 · Cited by 406 · see citing works

Gene-trap mutagenesis: past, present and beyond

Stanford, W. L., Cohn, J. B., & Cordes, S. P. (2001) · Nature Reviews Genetics · doi:10.1038/35093548 · Cited by 391 · see citing works

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.

Sasaki, K., Yagi, H., Bronson, R. T., Tominaga, K., Matsunashi, T., Deguchi, K., Tani, Y., Kishimoto, T., & Komori, T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12359 · Cited by 366 · see citing works

GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression

Gregory, T. C., Yu, C., Ma, A. I., Orkin, S. H., Blobel, G. A., & Weiss, M. J. (1999) · Blood · doi:10.1182/blood.v94.1.87.413k41_87_96 · Cited by 366 · see citing works

Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets

Vyas, P., Ault, K. A., Jackson, C. W., Orkin, S. H., & Shivdasani, R. A. (1999) · Blood · doi:10.1182/blood.v93.9.2867 · Cited by 357 · see citing works

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

Grass, J. A., Boyer, M. E., Pal, S. K., Wu, J., Weiss, M. J., & Bresnick, E. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432147100 · Cited by 357 · see citing works

CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

Blobel, G. A., Nakajima, T., Eckner, R., Montminy, M., & Orkin, S. H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2061 · Cited by 355 · see citing works

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOGPreprint

Tsang, A. P., Fujiwara, Y., Hom, D. B., & Orkin, S. H. (1998) · Genes & Development · doi:10.1101/gad.12.8.1176 · Cited by 350 · see citing works

Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line

Weiss, M. J., Yu, C., & Orkin, S. H. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1642 · Cited by 349 · see citing works

Development of hematopoietic cells lacking transcription factor GATA-1

Pevny, L., Lin, C., D’Agati, V. D., Simon, M. C., Orkin, S. H., & Costantini, F. D. (1995) · Development · doi:10.1242/dev.121.1.163 · Cited by 348 · see citing works

Severe Global DNA Hypomethylation Blocks Differentiation and Induces Histone Hyperacetylation in Embryonic Stem Cells

Jackson, M., Krassowska, A., Gilbert, N., Chevassut, T. J. T., Forrester, L. M., Ansell, J., & Ramsahoye, B. H. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.20.8862-8871.2004 · Cited by 345 · see citing works

Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping

Bartman, C. R., Hsu, S. C., Hsiung, C. C.-S., Raj, A., & Blobel, G. A. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.03.007 · Cited by 345 · see citing works

The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse.

Robb, L. G., Elwood, N. J., Elefanty, A. G., Köntgen, F., Li, R., Barnett, L. D., & Begley, C. G. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00787.x · Cited by 338 · see citing works

Requirement for p38α in Erythropoietin Expression

Tamura, K., SUDO, T., Senftleben, U., Dadak, A. M., Johnson, R. S., & Karin, M. (2000) · Cell · doi:10.1016/s0092-8674(00)00027-1 · Cited by 341 · see citing works

A GATA-1-regulated microRNA locus essential for erythropoiesis

Doré, L. C., Amigo, J. D., dos Santos, C. O., Zhang, Z., Gai, X., Tobias, J. W., Yu, D., Klein, A., Dorman, C. M., Wu, W.-S., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712312105 · Cited by 337 · see citing works

Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular developmentPreprint

Visvader, J. E., Fujiwara, Y., & Orkin, S. H. (1998) · Genes & Development · doi:10.1101/gad.12.4.473 · Cited by 325 · see citing works

The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine

Fukushige, T., Hawkins, M. G., & McGhee, J. D. (1998) · Developmental Biology · doi:10.1016/s0012-1606(98)80006-7 · Cited by 326 · see citing works

PI3k/AKT signaling pathway: Erythropoiesis and beyond

Jafari, M., Ghadami, E., Dadkhah, T., & Akhavan‐Niaki, H. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27262 · Cited by 325 · see citing works

Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis.

Weiss, M. J., & Orkin, S. H. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.21.9623 · Cited by 296 · see citing works

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

Lacaud, G. (2002) · Blood · doi:10.1182/blood-2001-12-0321 · Cited by 302 · see citing works

Developmental stage–selective effect of somatically mutated leukemogenic transcription factor GATA1

Li, Z., Godinho, F. J., Klusmann, J., Garriga-Canut, M., Yu, C., & Orkin, S. H. (2005) · Nature Genetics · doi:10.1038/ng1566 · Cited by 302 · see citing works

Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1

Ribeil, J., Zermati, Y., Vandekerckhove, J., Cathelin, S., Kersual, J., Dussiot, M., Coulon, S., Moura, I. C., Zeuner, A., Kirkegaard‐Sørensen, T., et al. (2006) · Nature · doi:10.1038/nature05378 · Cited by 297 · see citing works

Failure of Embryonic Hematopoiesis andLethal Hemorrhages in Mouse Embryos Heterozygousfor a Knocked-In Leukemia Gene CBFB–MYH11

Castilla, L. H., Wijmenga, C., Wang, Q., Stacy, T., Speck, N. A., Eckhaus, M., Marín-Padilla, M., Collins, F. S., Wynshaw-Boris, A., & Liu, P. P. (1996) · Cell · doi:10.1016/s0092-8674(00)81388-4 · Cited by 284 · see citing works

An abundant erythroid protein that stabilizes free α-haemoglobin

Kihm, A. J., Kong, Y., Wei, H., Russell, J., Rouda, S., Adachi, K., Simon, M. C., Blobel, G. A., & Weiss, M. J. (2002) · Nature · doi:10.1038/nature00803 · Cited by 276 · see citing works

GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein

Scherzer, C. R., Grass, J. A., Liao, Z., Pepivani, I., Zheng, B., Eklund, A. C., Ney, P. A., Ng, J., McGoldrick, M., Mollenhauer, B., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802437105 · Cited by 271 · see citing works

GATA Switches as Developmental Drivers

Bresnick, E. H., Lee, H., Fujiwara, T., Johnson, K. D., & Keleş, S. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.r110.159079 · Cited by 270 · see citing works

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

Fox, A. H., Liew, C. K., Holmes, M. L., Kowalski, K., Mackay, J. P., & Crossley, M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.10.2812 · Cited by 270 · see citing works

Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro

Soudais, C., Bielińska, M., Heikinheimo, M., MacArthur, C. A., Narita, N., Saffitz, J. E., Simon, M. C., Leiden, J. M., & Wilson, D. B. (1995) · Development · doi:10.1242/dev.121.11.3877 · Cited by 269 · see citing works

THE ROLE OF THE IKAROS GENE IN LYMPHOCYTE DEVELOPMENT AND HOMEOSTASIS

Georgopoulos, K., Winandy, S., & Avitahl, N. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.155 · Cited by 267 · see citing works

Characterization of zebrafish mutants with defects in embryonic hematopoiesis

Ransom, D. G., Haffter, P., Odenthal, J., Brownlie, A., Vogelsang, E., Kelsh, R. N., Brand, M., van Eeden, F. J. M., Furutani-Seiki, M., Granato, M., et al. (1996) · Development · doi:10.1242/dev.123.1.311 · Cited by 264 · see citing works

CREB-binding protein and p300: molecular integrators of hematopoietic transcription

Blobel, G. A. (2000) · Blood · doi:10.1182/blood.v95.3.745.003k05_745_755 · Cited by 256 · see citing works

Defects in Yolk Sac Hematopoiesis in Mll-Null Embryos

Hess, J. L., Yu, B., Li, B., Hanson, R., & Korsmeyer, S. J. (1997) · Blood · doi:10.1182/blood.v90.5.1799 · Cited by 254 · see citing works

GATA-5: A Transcriptional Activator Expressed in a Novel Temporally and Spatially-Restricted Pattern during Embryonic Development

Morrisey, E. E., Ip, H. S., Tang, Z., Lu, M. M., & Parmacek, M. S. (1997) · Developmental Biology · doi:10.1006/dbio.1996.8485 · Cited by 252 · see citing works

The emerging role of GATA transcription factors in development and disease

Lentjes, M. H. F. M., Niessen, H. E. C., Akiyama, Y., A, A. P. D. B., Melotte, V., & van Engeland, M. (2016) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2016.2 · Cited by 249 · see citing works

CREB-Binding Protein Acetylates Hematopoietic Transcription Factor GATA-1 at Functionally Important Sites

Hung, H.-L., Lau, J., Kim, A. Y., Weiss, M. J., & Blobel, G. A. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3496 · Cited by 247 · see citing works

Transcription factor networks in erythroid cell and megakaryocyte development

Doré, L. C., & Crispino, J. D. (2011) · Blood · doi:10.1182/blood-2011-04-285981 · Cited by 238 · see citing works

Characterization of a bipotent erythro-megakaryocytic progenitor in human bone marrow

Debili, N., Coulombel, L., Croisille, L., Katz, A., Guichard, J., Breton-Gorius, J., & Vainchenker, W. (1996) · Blood · doi:10.1182/blood.v88.4.1284.bloodjournal8841284 · Cited by 242 · see citing works

Loss of Gata1 but Not Gata2 Converts Erythropoiesis to Myelopoiesis in Zebrafish Embryos

Galloway, J. L., Wingert, R. A., Thisse, C., Thisse, B., & Zon, L. I. (2005) · Developmental Cell · doi:10.1016/j.devcel.2004.12.001 · Cited by 242 · see citing works

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

Lamonica, J. M., Deng, W., Kadauke, S., Campbell, A. E., Gamsjaeger, R., Wang, H., Cheng, Y., Billin, A. N., Hardison, R. C., Mackay, J. P., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102140108 · Cited by 244 · see citing works

The Role of HOX Homeobox Genes in Normal and Leukemic Hematopoiesis

Lawrence, H. J., Sauvageau, G., Humphries, R. K., & Largman, C. (1996) · Stem Cells · doi:10.1002/stem.140281 · Cited by 241 · see citing works

Enforced Expression of the GATA-2 Transcription Factor Blocks Normal Hematopoiesis

Persons, D. A., Allay, J. A., Allay, E. R., Ashmun, R. A., Orlic, D., Jane, S. M., Cunningham, J. M., & Nienhuis, A. W. (1999) · Blood · doi:10.1182/blood.v93.2.488 · Cited by 240 · see citing works

Use of Altered Specificity Mutants to Probe a Specific Protein–Protein Interaction in Differentiation

Crispino, J. D., Lodish, M. B., Mackay, J. P., & Orkin, S. H. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80312-3 · Cited by 237 · see citing works

Tissue-Specific Mitotic Bookmarking by Hematopoietic Transcription Factor GATA1

Kadauke, S., Udugama, M., Pawlicki, J. M., Achtman, J. C., Jain, D., Cheng, Y., Hardison, R. C., & Blobel, G. A. (2012) · Cell · doi:10.1016/j.cell.2012.06.038 · Cited by 232 · see citing works

Locus control regions of mammalian β-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

Hardison, R., Slightom, J. L., Gumucio, D. L., Goodman, M., Stojanovic, N., & Miller, W. (1997) · Gene · doi:10.1016/s0378-1119(97)00474-5 · Cited by 230 · see citing works

The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineagesPreprint

Saleque, S., Cameron, S., & Orkin, S. H. (2002) · Genes & Development · doi:10.1101/gad.959102 · Cited by 231 · see citing works

Blood island formation: longstanding observations and modern interpretations

Ferkowicz, M. J., & Yöder, M. C. (2005) · Experimental Hematology · doi:10.1016/j.exphem.2005.06.006 · Cited by 231 · see citing works

Apoptotic mechanisms in the control of erythropoiesis

Testa, U. (2004) · Leukemia · doi:10.1038/sj.leu.2403383 · Cited by 229 · see citing works

Transcription Factors and Hematopoietic Development

Orkin, S. H. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.10.4955 · Cited by 225 · see citing works

Targeted null-mutation in the vascular endothelial–cadherin gene impairs the organization of vascular-like structures in embryoid bodies

Vittet, D., Buchou, T., Schweitzer, A., Dejana, E., & Huber, P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6273 · Cited by 227 · see citing works

A “knockdown” mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1

McDevitt, M. A., Shivdasani, R. A., Fujiwara, Y., Yang, H., & Orkin, S. H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.13.6781 · Cited by 222 · see citing works

In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors

Nakano, T., Kodama, H., & Honjo, T. (1996) · Science · doi:10.1126/science.272.5262.722 · Cited by 225 · see citing works

Hematopoietic mutations in the zebrafish

Weinstein, B. M., Schier, A. F., Abdelilah, S., Malicki, J. J., Solnica-Krezel, L., Stemple, D. L., Stainier, D. Y. R., Zwartkruis, F. J. T., Driever, W., & Fishman, M. C. (1996) · Development · doi:10.1242/dev.123.1.303 · Cited by 223 · see citing works

Expression and Hormonal Regulation of Transcription Factors GATA-4 and GATA-6 in the Mouse Ovary1

Heikinheimo, M., Ermolaeva, M. V., Bielińska, M., Rahman, N. A., Narita, N., Huhtaniemi, I. T., Tapanainen, J. S., & Wilson, D. B. (1997) · Endocrinology · doi:10.1210/endo.138.8.5350 · Cited by 222 · see citing works

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus

Jing, H., Vakoc, C. R., Ying, L., Mandat, S. A., Wang, H., Zheng, X., & Blobel, G. A. (2008) · Molecular Cell · doi:10.1016/j.molcel.2007.11.020 · Cited by 213 · see citing works

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors

Göttgens, B., Nastos, A., Kinston, S., Piltz, S., Delabesse, E. C. M., Stanley, M., Sanchez, M., Ciau‐Uitz, A., Patient, R., & Green, A. R. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf286 · Cited by 212 · see citing works

The c‐myc Promoter: Still MysterY and Challenge

(2008) · Advances in Cancer Research · doi:10.1016/s0065-230x(07)99004-1 · Cited by 211 · see citing works

Regulation of human fetal hemoglobin: new players, new complexities

Bank, A. (2005) · Blood · doi:10.1182/blood-2005-05-2113 · Cited by 211 · see citing works

FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped

Tevosian, S. G., Deconinck, A. E., Cantor, A. B., Rieff, H. I., Fujiwara, Y., Corfas, G., & Orkin, S. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.3.950 · Cited by 210 · see citing works

Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly

Wagner, K., Claudio, E., Rucker, E. B., Riedlinger, G., Broussard, C., Schwartzberg, P. L., Siebenlist, U. K., & Hennighausen, L. G. (2000) · Development · doi:10.1242/dev.127.22.4949 · Cited by 205 · see citing works

Erythropoiesis: Model systems, molecular regulators, and developmental programs

Tsiftsoglou, A. S., Vizirianakis, I. S., & Strouboulis, J. (2009) · IUBMB Life · doi:10.1002/iub.226 · Cited by 199 · see citing works

GATA1 in normal and malignant hematopoiesis

Crispino, J. D. (2004) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2004.11.002 · Cited by 199 · see citing works

The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200–dependent pathway in mice

Yang, Y., Ahn, Y., Gibbons, D. L., Zang, Y., Lin, W., Thilaganathan, N., Alvarez, C. A., Moreira, D. C., Creighton, C. J., Gregory, P. A., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci42579 · Cited by 196 · see citing works

GATA-1-Mediated Proliferation Arrest during Erythroid Maturation

Rylski, M., Welch, J. J., Chen, Y., Letting, D. L., Diehl, J. A., Chodosh, L. A., Blobel, G. A., & Weiss, M. J. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.14.5031-5042.2003 · Cited by 195 · see citing works

Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway

Zhao, W., Kitidis, C., Fleming, M. D., Lodish, H. F., & Ghaffari, S. (2005) · Blood · doi:10.1182/blood-2005-06-2516 · Cited by 193 · see citing works

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.

Osada, H., Grutz, G., Axelson, H., Forster, A., & Rabbitts, T. H. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.21.9585 · Cited by 192 · see citing works

3 Ontogeny of hematopoiesis: Examining the emergence of hematopoietic cells in the vertebrate embryo

Galloway, J. L., & Zon, L. I. (2003) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)53004-6 · Cited by 186 · see citing works

Self-Association of the Erythroid Transcription Factor GATA-1 Mediated by Its Zinc Finger Domains

Crossley, M., Merika, M., & Orkin, S. H. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.5.2448 · Cited by 183 · see citing works

Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor

Niki, M., Okada, H., Takano, H., Kuno, J., Tani, K., Hibino, H., Asano, S., Ito, Y., Satake, M., & Noda, T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.11.5697 · Cited by 181 · see citing works

Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region–derived stromal cells

Matsuoka, S., Tsuji, K., Hisakawa, H., Xu, M., Ebihara, Y., Ishii, T., Sugiyama, D., Manabe, A., Tanaka, R., Ikeda, Y., et al. (2001) · Blood · doi:10.1182/blood.v98.1.6 · Cited by 182 · see citing works

Developmental regulation of erythropoietin and erythropoiesis

Moritz, K. M., Lim, G. B., & Wintour, E. M. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.273.6.r1829 · Cited by 180 · see citing works

Pax3 functions in cell survival and in pax7 regulation

Borycki, A., Li, J., Jin, F., Emerson, C. P., & Epstein, J. A. (1999) · Development · doi:10.1242/dev.126.8.1665 · Cited by 179 · see citing works

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

Fujiwara, Y., Browne, C. P., Cunniff, K., Goff, S. C., & Orkin, S. H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12355 · Cited by 778 · see citing works

GATA-1 Regulates Growth and Differentiation of Definitive Erythroid Lineage Cells During In Vitro ES Cell Differentiation

Suwabe, N., Takahashi, S., Nakano, T., & Yamamoto, M. P. (1998) · Blood · doi:10.1182/blood.v92.11.4108 · Cited by 75 · see citing works

Development of hematopoietic cells lacking transcription factor GATA-1

Pevny, L., Lin, C., D’Agati, V. D., Simon, M. C., Orkin, S. H., & Costantini, F. D. (1995) · Development · doi:10.1242/dev.121.1.163 · Cited by 348 · see citing works

Knock-out Effects of Transcription Factor GATA-1 on Early Erythropoiesis

Kim, C. G. (1996) · Molecules and Cells · doi:10.1016/s1016-8478(23)10986-1 · Cited by 6 · see citing works

Rescue of erythroid development in gene targeted GATA–1− mouse embryonic stem cells

Simon, M. C., Pevny, L., Wiles, M. V., Keller, G. M., Costantini, F. D., & Orkin, S. H. (1992) · Nature Genetics · doi:10.1038/ng0592-92 · Cited by 248 · see citing works