Cited by 541Hematopoietic Stem Cell TransplantationHemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

The DOI matches its Crossref record; 82 of the 84 references it cites were found in a registry or an index.

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

Open access

Weiss, M J, Keller, G, Orkin, S H·1994·Genes & Development

DOI 10.1101/gad.8.10.1184

Open this paper in CoChat — free account Open PDF

Abstract

Mouse embryonic stem (ES) cells lacking the transcription factor GATA-1 do not produce mature red blood cells either in vivo or in vitro. To define the consequences of GATA-1 loss more precisely, we used an in vitro ES cell differentiation assay that permits enumeration of primitive (EryP) and definitive (EryD) erythroid precursors and recovery of pure erythroid colonies. In contrast to normal ES cells, GATA-1- ES cells fail to generate EryP precursors. EryD precursors, however, are normal in number but undergo developmental arrest and death at the proerythroblast stage. Contrary to initial expectations, arrested GATA-1(-)-definitive proerythroblasts express GATA target genes at normal levels. Transcripts of the related factor GATA-2 are remarkably elevated in GATA-1- proerythroblasts. These findings imply substantial interchangeability of GATA factors in vivo and suggest that GATA-1 normally serves to repress GATA-2 during erythropoiesis. The approach used here is a paradigm for the phenotypic analysis of targeted mutations affecting hematopoietic development.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1101/gad.8.10.1184

Cites

82 of 82 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,515
Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia
Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956
Altering the Genome by Homologous Recombination
Capecchi, M. R. (1989) · Science · doi:10.1126/science.2660260 · Cited by 2,037
The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium
Doetschman, T., Eistetter, H. R., Katz, M., Schmidt, W., & Kemler, R. (1985) · Development · doi:10.1242/dev.87.1.27 · Cited by 1,962
Position-independent, high-level expression of the human β-globin gene in transgenic mice
Grosveld, F. G., van Assendelft, G. B., Greaves, D. R., & Kollias, G. A. (1987) · Cell · doi:10.1016/0092-8674(87)90584-8 · Cited by 1,908
Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene
Hasty, P., Bradley, A., Morris, J. H., Edmondson, D. G., Venuti, J. M., Olson, E. N., & Klein, W. H. (1993) · Nature · doi:10.1038/364501a0 · Cited by 1,364
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
Pevny, L., Simon, M. C., Robertson, E., Klein, W. H., Tsai, S.-F., D'Agati, V., Orkin, S. H., & Costantini, F. (1991) · Nature · doi:10.1038/349257a0 · Cited by 1,308
Self-citation
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
Mucenski, M. L., McLain, K., Kier, A. B., Swerdlow, S. H., Schreiner, C. M., Miller, T. A., Pietryga, D. W., Scott, W. J., & Potter, S. S. (1991) · Cell · doi:10.1016/0092-8674(91)90099-k · Cited by 1,028
Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development
Rudnicki, M. A., Braun, T. W., Hinuma, S., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90508-a · Cited by 984
Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination
Smithies, O., Gregg, R. G., Boggs, S. S., Koralewski, M. A., & Kucherlapati, R. (1985) · Nature · doi:10.1038/317230a0 · Cited by 977
Myogenin gene disruption results in perinatal lethality because of severe muscle defect
Nabeshima, Y., Hanaoka, K., Hayasaka, M., Esuml, E., Li, S., Nonaka, I., & Nabeshima, Y.-I. (1993) · Nature · doi:10.1038/364532a0 · Cited by 954
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells
Tsai, S., Martin, D. I. K., Zon, L. I., D’Andrea, A. D., Wong, G. G., & Orkin, S. H. (1989) · Nature · doi:10.1038/339446a0 · Cited by 884
Self-citation
GATA-binding transcription factors in hematopoietic cells
Orkin, S. (1992) · Blood · doi:10.1182/blood.v80.3.575.575 · Cited by 884
Self-citation
Hematopoietic Commitment During Embryonic Stem Cell Differentiation in Culture
Keller, G. M., Kennedy, M. A., Papayannopoulou, T., & Wiles, M. V. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.1.473 · Cited by 874
Self-citation
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
Robertson, E. J., Bradley, A., Kuehn, M. R., & Evans, M. J. (1986) · Nature · doi:10.1038/323445a0 · Cited by 751
Expression cloning of the murine erythropoietin receptor
D’Andrea, A. D., Lodish, H. F., & Wong, G. G. (1989) · Cell · doi:10.1016/0092-8674(89)90965-3 · Cited by 737
A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†
Miller, I. J., & Bieker, J. J. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.5.2776-2786.1993 · Cited by 732
DNA-Binding Specificity of GATA Family Transcription Factors
Merika, M., & Orkin, S. H. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.7.3999-4010.1993 · Cited by 660
Self-citation
Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies
Risau, W., Sariola, H. V., Zerwes, H., Sasse, J., Ekblom, P., Kemler, R., & Doetschman, T. (1988) · Development · doi:10.1242/dev.102.3.471 · Cited by 656
Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates
Alonso, S., Minty, A. J., Bourlet, Y., & BUCKINGHAM, M. E. (1986) · Journal of Molecular Evolution · doi:10.1007/bf02100994 · Cited by 643
Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.Preprint
Yamamoto, M. P., Ko, L. J., Leonard, M. W., Beug, H., Orkin, S. H., & Engel, J. D. (1990) · Genes & Development · doi:10.1101/gad.4.10.1650 · Cited by 598
Self-citation
Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture
Wiles, M. V., & Keller, G. M. (1991) · Development · doi:10.1242/dev.111.2.259 · Cited by 597
Self-citation
The erythroid-specific transcription factor eryf1: A new finger protein
Evans, T., & Felsenfeld, G. (1989) · Cell · doi:10.1016/0092-8674(89)90940-9 · Cited by 580
DNA-Binding Specificities of the GATA Transcription Factor Family
Ko, L. J., & Engel, J. D. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.7.4011-4022.1993 · Cited by 575
An early pre-liver intraembryonic source of CFU-S in the developing mouse
Medvinskiĭ, A. L., Samoylina, N. L., Müller, A. M., & Dzierzak, E. A. (1993) · Nature · doi:10.1038/364064a0 · Cited by 507
An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.
Evans, T., Reitman, M. L., & Felsenfeld, G. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.16.5976 · Cited by 485
New light on Myc and Myb. Part II. Myb.Preprint
Lüscher, B., & Eisenman, R. N. (1990) · Genes & Development · doi:10.1101/gad.4.12b.2235 · Cited by 475
Globin gene regulation and switching: Circa 1990
Orkin, S. H. (1990) · Cell · doi:10.1016/0092-8674(90)90133-y · Cited by 462
Self-citation
Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages
Martin, D. I. K., Zon, L. I., Mutter, G. L., & Orkin, S. H. (1990) · Nature · doi:10.1038/344444a0 · Cited by 455
Self-citation
A c- myb Antisense Oligodeoxynucleotide Inhibits Normal Human Hematopoiesis in Vitro
Gewirtz, A. M., & Calabretta, B. (1988) · Science · doi:10.1126/science.2461588 · Cited by 424
Megakaryocytic and erythrocytic lineages share specific transcription factors
Roméo, P., Prandini, M., Joulin, V., Mignotte, V., Prenant, M., Vainchenker, W., Marguerie, G., & Uzan, G. (1990) · Nature · doi:10.1038/344447a0 · Cited by 417
The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites
Konkel, D. A., Tilghman, S. M., & Leder, P. (1978) · Cell · doi:10.1016/0092-8674(78)90040-5 · Cited by 406
Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors
Godin, I., García‐Porrero, J. A., Coutinho, A., Dieterlen‐Lièvre, F., & Marcos, M. A. R. (1993) · Nature · doi:10.1038/364067a0 · Cited by 387
Quantitative or semi-quantitative PCR: reality versus myth.Preprint
Ferre, F. (1992) · Genome Research · doi:10.1101/gr.2.1.1 · Cited by 350
Human GATA‐3: a lineage‐restricted transcription factor that regulates the expression of the T cell receptor alpha gene.
Ho, I., Vorhees, P., Marín, N., Oakley, B. K., Tsai, S., Orkin, S. H., & Leiden, J. M. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb08059.x · Cited by 349
Self-citation
The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.
Begley, C. G., Aplan, P. D., Denning, S. M., Haynes, B. F., Waldmann, T. A., & Kirsch, I. R. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.10128 · Cited by 346
A major positive regulatory region located far upstream of the human alpha-globin gene locus.Preprint
Higgs, D. R., Wood, W. G., Jarman, A. P., Sharpe, J. A., Lida, J., Pretorius, I., & Ayyub, H. (1990) · Genes & Development · doi:10.1101/gad.4.9.1588 · Cited by 335
Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression.Preprint
Schmitt, R. M., Bruyns, E., & Snodgrass, H. R. (1991) · Genes & Development · doi:10.17615/zjcs-ew77 · Cited by 321
Detailed analysis of the site 3 region of the human beta‐globin dominant control region.
Talbot, D., Philipsen, S., Fraser, P., & Grosveld, F. G. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07386.x · Cited by 311
Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation.
Clarke, M. F., Kukowska‐Latallo, J. F., Westin, E. H., Smith, M. J., & Prochownik, E. V. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.2.884 · Cited by 299
The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution
Nishioka, Y., & Leder, P. (1979) · Cell · doi:10.1016/0092-8674(79)90139-9 · Cited by 298
Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer.
Ko, L. J., Yamamoto, M. P., Leonard, M. W., George, K. M., Ting, P., & Engel, J. D. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.5.2778 · Cited by 293
The beta‐globin dominant control region: hypersensitive site 2.
Philipsen, S., Talbot, D., Fraser, P., & Grosveld, F. G. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07385.x · Cited by 281
Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.
Dorfman, D. M., Wilson, D. B., Bruns, G. A. P., & Orkin, S. H. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48426-8 · Cited by 278
Self-citation
Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants
Konecki, D. S., Brennand, J. C., Fuscoe, J. C., Caskey, C. T., & Chinault, A. C. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.21.6763 · Cited by 275
Increased γ-globin expression in a nondeletion HPFH mediated by an erythroid-specif ic DNA-binding factor
Martin, D. I. K., Tsai, S., & Orkin, S. H. (1989) · Nature · doi:10.1038/338435a0 · Cited by 274
Self-citation
Rescue of erythroid development in gene targeted GATA–1− mouse embryonic stem cells
Simon, M. C., Pevny, L., Wiles, M. V., Keller, G. M., Costantini, F. D., & Orkin, S. H. (1992) · Nature Genetics · doi:10.1038/ng0592-92 · Cited by 251
Self-citation
Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development
Wang, R., Clark, R., & Bautch, V. L. (1992) · Development · doi:10.1242/dev.114.2.303 · Cited by 238
Dynamics of GATA transcription factor expression during erythroid differentiation
Leonard, M. O., Brice, M. C., Engel, J., & Papayannopoulou, T. (1993) · Blood · doi:10.1182/blood.v82.4.1071.1071 · Cited by 237
The SCL gene product: a positive regulator of erythroid differentiation.
Aplan, P. D., Nakahara, K., Orkin, S. H., & Kirsch, I. R. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05500.x · Cited by 230
Self-citation
The 5′HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF‐E2 binding sites.
Talbot, D., & Grosveld, F. G. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07659.x · Cited by 226
Activation of the erythropoietin receptor promoter by transcription factor GATA-1.
Zon, L. I., Youssoufian, H., Mather, C., Lodish, H. F., & Orkin, S. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.23.10638 · Cited by 221
Self-citation
Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.Preprint
Briegel, K. J., Lim, K. C., Plank, C., Beug, H., Engel, J. D., & Zenke, M. (1993) · Genes & Development · doi:10.1101/gad.7.6.1097 · Cited by 204
Expression and function of CD4 in a murine T-cell hybridoma
Sleckman, B. P., Peterson, A. S., Jones, W. K., Foran, J. A., Greenstein, J. L., Seed, B., & Burakoff, S. J. (1987) · Nature · doi:10.1038/328351a0 · Cited by 200
A T‐cell specific TCR delta DNA binding protein is a member of the human GATA family.
Joulin, V., Bories, D., Eléouët, J., Labastie, M.-C., Chrétien, S., Mattéi, M., & Roméo, P. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07706.x · Cited by 172
Characterization of the Major Regulatory Element Upstream of the Human a-Globin Gene Cluster
Jarman, A. P., Wood, W. G., Sharpe, J. A., Gourdon, G., Ayyub, H., & Higgs, D. R. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.9.4679-4689.1991 · Cited by 171
In vitro chamber specification during embryonic stem cell cardiogenesis. Expression of the ventricular myosin light chain-2 gene is independent of heart tube formation.
Miller‐Hance, W. C., LaCorbiere, M., Fuller, S. J., Evans, S. Μ., Lyons, G. E., Schmidt, C., Robbins, J. M., & Chien, K. R. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74594-3 · Cited by 170
Hemoglobin ontogeny during normal mouse fetal development.
Brotherton, T. W., Chui, D. H. K., Gauldie, J., & Patterson, M. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.6.2853 · Cited by 170
Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation.
Todokoro, K., Watson, R. J., Higo, H., Amanuma, H., Kuramochi, S., Yanagisawa, H., & Ikawa, Y. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.23.8900 · Cited by 168
A Nonerythroid GATA-Binding Protein Is Required for Function of the Human Preproendothelin-1 Promoter in Endothelial Cells
Wilson, D. B., Dorfman, D. M., & Orkin, S. H. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.9.4854-4862.1990 · Cited by 167
Self-citation
Expression of GATA-binding proteins during embryonic development in Xenopus laevis.
Zon, L. I., Mather, C., Burgess, S., Bolce, M. E., Harland, R. M., & Orkin, S. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.23.10642 · Cited by 166
Self-citation
Regulated Expression of Globin Chains and the Erythroid Transcription Factor GATA-1 during Erythropoiesis in the Developing Mouse
Whitelaw, E., Tsai, S., Hogben, P., & Orkin, S. H. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.12.6596-6606.1990 · Cited by 163
Self-citation
Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.
Jiménez, G., Griffiths, S. D., Ford, A. M., Greaves, M. F., & Enver, T. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.10618 · Cited by 157
GATAAG; acis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression
Plumb, M., Frampton, J., Wainwright, H., Walker, M., Macleod, K. F., Goodwin, G. H., & Harrison, P. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.1.73 · Cited by 143
Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors.
Sposi, N. M., Zon, L. I., Carè, A., Valtieri, M., Testa, U., Gabbianelli, M., Mariani, G., Bottero, L., Mather, C., & Orkin, S. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.14.6353 · Cited by 142
Self-citation
Death-defying acts: a meeting review on apoptosis.Preprint
White, E. (1993) · Genes & Development · doi:10.1101/gad.7.12a.2277 · Cited by 128
Developmental Analysis of Tropomyosin Gene Expression in Embryonic Stem Cells and Mouse Embryos
Muthuchamy, M., Pajak, L., Howles, P. N., Doetschman, T., & Wieczorek, D. F. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3311 · Cited by 126
Synthetic human beta‐globin 5′HS2 constructs function as locus control regions only in multicopy transgene concatamers.
Ellis, J., Talbot, D., Dillon, N., & Grosveld, F. G. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05638.x · Cited by 121
Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene.
Mcclinton, D., Stafford, J., Brents, L. A., Bender, T. P., & Kuehl, W. M. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.2.705 · Cited by 96
The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region.
Philipsen, S., Pruzina, S., & Grosveld, F. G. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb05749.x · Cited by 95
Early fetal hematopoietic development from in vitro differentiated embryonic stem cells.
Burkert, U., von Rüden, T., & Wagner, E. F. (1991) · PubMed · Cited by 94
The erythroid-specific protein cGATA-1 mediates distal enhancer activity through a specialized beta-globin TATA box.Preprint
Fong, T., & Emerson, B. M. (1992) · Genes & Development · doi:10.1101/gad.6.4.521 · Cited by 93
trans-Activation of a globin promoter in nonerythroid cells.
Evans, T., & Felsenfeld, G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.2.843 · Cited by 92
Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL.
Begley, C. G., Visvader, J. E., Green, A. R., Aplan, P. D., Metcalf, D., Kirsch, I. R., & Gough, N. M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.3.869 · Cited by 76
Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.
Hill, A., Hardies, S. C., Phillips, S. J., Davis, M. G., Hutchison, C. A., & Edgell, M. H. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43157-7 · Cited by 68
Structural organization and nucleotide sequence of mouse c-myboncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5′ coding sequences
Lavu, S., & Reddy, E. P. (1986) · Nucleic Acids Research · doi:10.1093/nar/14.13.5309 · Cited by 59
Identification and characterization of a chicken alpha-globin enhancer.
Knezetic, J. A., & Felsenfeld, G. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.3.893 · Cited by 54
In situ hybridization reveals co-expression of embryonic and adult α globin genes in the earliest murine erythrocyte progenitors
Leder, A., Kuo, A., Shen, M. M., & Leder, P. (1992) · Development · doi:10.1242/dev.116.4.1041 · Cited by 52
The sequence of a mouse embryonic beta-globin gene. Evolution of the gene and its signal region.
HANSEN, J. N., Konkel, D. A., & Leder, P. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)68306-7 · Cited by 51
A factor binding GATAAG confers tissue specificity on the promoter of the humanζ-globin gene
Watt, P. M., Lamb, P., Squire, L., & Proudfoot, N. J. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.6.1339 · Cited by 48
Characterization, Expression, and Evolution of the Mouse Embryonic ζ-Globin Gene
Leder, A., Weir, L., & Leder, P. (1985) · Molecular and Cellular Biology · doi:10.1128/mcb.5.5.1025-1033.1985 · Cited by 42
Erythropoietin triggers a burst of GATA-1 in normal human erythroid cells differentiating in tissue culture
Dalyot-Herman, N., Fibach, E., Ronchi, A. E., Rachmilewitz, E. A., Ottolenghi, S., & Oppenheim, A. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.17.4031 · Cited by 29

Research works printed but not linked: 4

10.1016/0003-2697(87)90021-2 · DOI
10.1101/gad.5.5.728 · DOI
10.1128/MCB.10.9.4854 · DOI
Wood, W.G. 1982. Erythropoiesis and haemoglobin production during development. In Biochemical development of the fetus and neonate (ed. C.T. Jones), pp. 127–162. Elsevier Biomedical Press, New York.

Sorted by citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L., & Schuh, A. C. (1995) · Nature · doi:10.1038/376062a0 · Cited by 3,931
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.
Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G., & Downing, J. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80986-1 · Cited by 1,856
An early haematopoietic defect in mice lacking the transcription factor GATA-2
Tsai, F., Keller, G. M., Kuo, F. C., Weiss, M. J., Chen, J., Rosenblatt, M., Alt, F. W., & Orkin, S. H. (1994) · Nature · doi:10.1038/371221a0 · Cited by 1,419
Self-citation
Embryonic stem cell differentiation: emergence of a new era in biology and medicinePreprint
Keller, G. M. (2005) · Genes & Development · doi:10.1101/gad.1303605 · Cited by 1,174
Self-citation

See all 541

Authors: Weiss, M. J., Keller, G., & Orkin, S. H.
Affiliations: Dana-Farber Cancer Institute (US)
ORCID: Weiss, M J
Keller, G
Orkin, S H
Venue: Genes & Development
Publisher: Cold Spring Harbor Laboratory
Published: 1994-05-15
Volume: 8
Issue: 10
Pages: 1184-1197
ISSN: 0890-9369 (ISSN-L)
1549-5477
DOI: 10.1101/gad.8.10.1184
OpenAlex: W2147951044
Cited by: 541
References: 84
Citations by year: 2026: 1 · 2025: 2 · 2024: 5 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 4 · 2017: 5 · 2016: 7 · 2015: 1 · 2014: 6 · 2013: 14 · 2012: 14
Type: posted content
Language: en
Open access: bronze
doi.org
Locations: Genes & Development (publishedVersion)
PubMed (publishedVersion)
Funders: Howard Hughes Medical Institute
Amgen
National Institutes of Health (5r01dk043285-03)
National Institute of Diabetes and Digestive and Kidney Diseases (R01 DK-43285)
Topics: Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
Health Sciences › Medicine › Genetics (clinical) › Hemoglobinopathies and Related Disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Keywords: erythroid development, GATA-1, GATA2, embryonic stem cells, erythropoiesis, erythroid precursors, proerythroblasts, transcriptional repression, hematopoietic development, targeted mutations
MeSH terms: Animals, Base Sequence, Cell Differentiation, Cell Line, DNA-Binding Proteins, Erythroblasts, Erythropoiesis, Globins, Hematopoietic Stem Cells, Molecular Sequence Data, Proto-Oncogene Proteins, RNA, Messenger, Transcription Factors, Trans-Activators, Erythroid Precursor Cells, Up-Regulation, Cell Death, Gene Expression Regulation, Developmental, Proto-Oncogene Proteins c-myb, Erythroid-Specific DNA-Binding Factors, GATA1 Transcription Factor, GATA2 Transcription Factor, GATA3 Transcription Factor, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks