Keller, Gordon

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

MacParland, S. A., Liu, J. C., Ma, X.-Z., Innes, B. T., Bartczak, A. M., Gage, B. K., Manuel, J., Khuu, N., Echeverri, J., Linares, I., et al. (2018) · Nature Communications

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 1,552

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

Yang, L., Soonpaa, M. H., Adler, E. D., Roepke, T. K., Kattman, S. J., Kennedy, M., Henckaerts, E., Bonham, K., Abbott, G. W., Linden, R. M., et al. (2008) · Nature

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 1,389

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

Kattman, S. J., Witty, A. D., Gagliardi, M., Dubois, N. C., Niapour, M., Hotta, A., Ellis, J., & Keller, G. (2011) · Cell Stem Cell

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 1,159

Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

Nunes, S. S., Miklas, J. W., Liu, J., Aschar-Sobbi, R., Xiao, Y., Zhang, B., Jiang, J., Massé, S., Gagliardi, M., Hsieh, A., et al. (2013) · Nature Methods

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 952

Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming

Burridge, P. W., Keller, G., Gold, J. D., & Wu, J. C. (2012) · Cell Stem Cell

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 670

A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling

Zhao, Y., Rafatian, N., Feric, N. T., Cox, B. J., Aschar-Sobbi, R., Wang, E. Y., Aggarwal, P., Zhang, B., Conant, G., Ronaldson-Bouchard, K., et al. (2019) · Cell

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 610

Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis

Zhang, B., Montgomery, M., Chamberlain, M. D., Ogawa, S., Korolj, A., Pahnke, A., Wells, L. A., Massé, S., Kim, J., Reis, L., et al. (2016) · Nature Materials

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 593

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

Weiss, M. J., Keller, G., & Orkin, S. H. (1994) · Genes & Development

Hematopoietic Stem Cell TransplantationHemoglobinopathies and Related Disorders

Cited by 541

Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures

Kennedy, M., D'Souza, S. L., Lynch-Kattman, M., Schwantz, S., & Keller, G. (2007) · Blood

Hematopoietic Stem Cell TransplantationPluripotent Stem Cells Research

Cited by 483

Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation

Wang, J., Gallagher, D., DeVito, L. M., Cancino, G. I., Tsui, D., He, L., Keller, G. M., Frankland, P. W., Kaplan, D. R., & Miller, F. D. (2012) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 474

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

Sturgeon, C. M., Ditadi, A., Awong, G., Kennedy, M., & Keller, G. (2014) · Nature Biotechnology

Pluripotent Stem Cells ResearchHematopoietic Stem Cell Transplantation

Cited by 467

Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker

Protze, S. I., Liu, J., Nussinovitch, U., Ohana, L., Backx, P. H., Gepstein, L., & Keller, G. M. (2017) · Nature Biotechnology

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 366

Design and formulation of functional pluripotent stem cell-derived cardiac microtissues

Thavandiran, N., Dubois, N., Mikryukov, A., Massé, S., Beca, B., Simmons, C. A., Deshpande, V. S., McGarry, J. P., Chen, C. S., Nanthakumar, K., et al. (2013) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 285

The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes

Mihic, A., Li, J., Miyagi, Y., Gagliardi, M., Li, S.-H., Zu, J., Weisel, R. D., Keller, G., & Li, R.-K. (2014) · Biomaterials

Tissue Engineering and Regenerative MedicinePluripotent Stem Cells Research

Cited by 248

Retinoic Acid Signaling Is Essential for Embryonic Hematopoietic Stem Cell Development

Chanda, B., Ditadi, A., Iscove, N. N., & Keller, G. (2013) · Cell

Hematopoietic Stem Cell TransplantationRetinoids in leukemia and cellular processes

Cited by 201

The β-Globin LCR Is Not Necessary for an Open Chromatin Structure or Developmentally Regulated Transcription of the Native Mouse β-Globin Locus

Epner, E., Reik, A., Cimbora, D., Telling, A., Bender, M. A., Fiering, S., Enver, T., Martin, D. I. K., Kennedy, M., Keller, G., et al. (1998) · Molecular Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 183

Generation of the epicardial lineage from human pluripotent stem cells

Witty, A. D., Mihic, A., Tam, R. Y., Fisher, S. A., Mikryukov, A., Shoichet, M. S., Li, R.-K., Kattman, S. J., & Keller, G. (2014) · Nature Biotechnology

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 180

Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes

Lieu, D. K., Fu, J.-D., Chiamvimonvat, N., Tung, K. C., McNerney, G. P., Huser, T., Keller, G., Kong, C.-W., & Li, R. A. (2013) · Circulation: Arrhythmia and Electrophysiology

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 179

Human Pluripotent Stem Cell-Derived Cardiovascular Cells: From Developmental Biology to Therapeutic Applications

Protze, S. I., Lee, J. H., & Keller, G. M. (2019) · Cell Stem Cell

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 162

Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes

Ogawa, S., Surapisitchat, J., Virtanen, C., Ogawa, M., Niapour, M., Sugamori, K. S., Wang, S., Tamblyn, L., Guillemette, C., Hoffmann, E., et al. (2013) · Development

Pluripotent Stem Cells ResearchDrug-Induced Hepatotoxicity and Protection

Cited by 161

Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells

Grigoriadis, A. E., Kennedy, M., Bozec, A., Brunton, F., Stenbeck, G., Park, I.-H., Wagner, E. F., & Keller, G. M. (2010) · Blood

Bone Metabolism and DiseasesPluripotent Stem Cells Research

Cited by 151