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Une exposition à l'ozone induit une insulino-résistance via un stress oxydant systémique et un stress du réticulum endoplasmique musculaire : pollution à l'ozone et diabète de type 2 : peut-on imaginer une origine environnementale aux maladies métaboliques ?

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Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration

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Lrsam1 deficiency suppresses osteoclastogenesis and attenuates bone loss through the JNK2-NFATc1 axis

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c-Jun N-Terminal Kinase: A Spatiotemporal Regulator of Cell Fate and Function

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BindingDB Entry 50005433: Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.

BindingDB (2020) · UC San Diego · doi:10.7270/q2mg7sf1

BindingDB Entry 5483: Discovery of potent and selective covalent inhibitors of JNK.

BindingDB (2012) · UC San Diego · doi:10.7270/q2k35s8x

BindingDB Entry 2004: The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity.

BindingDB (2007) · UC San Diego · doi:10.7270/q2dj5cwz

BindingDB Entry 1802: Synthesis and mixed lineage kinase activity of pyrrolocarbazole and isoindolone analogs of (+)k-252a.

BindingDB (2007) · UC San Diego · doi:10.7270/q2ht2mjx

BindingDB Entry 50031494: Small molecule JNK (c-Jun N-terminal kinase) inhibitors.

BindingDB (2010) · UC San Diego · doi:10.7270/q2ks6rp5

BindingDB Entry 50032621: Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK.

BindingDB (2011) · UC San Diego · doi:10.7270/q20865jw

BindingDB Entry 50040956: Discovery of a novel series of 4-quinolone JNK inhibitors.

BindingDB (2013) · UC San Diego · doi:10.7270/q27s7pz6

BindingDB Entry 2811: Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models.

BindingDB (2008) · UC San Diego · doi:10.7270/q2th8k09

BindingDB Entry 50033020: Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor.

BindingDB (2011) · UC San Diego · doi:10.7270/q2q52px0

BindingDB Entry 1932: Structural basis of inhibitor selectivity in MAP kinases.

BindingDB (2007) · UC San Diego · doi:10.7270/q2xp7351

BindingDB Entry 50043367: Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): kinase profiling guided optimization of a 1,2,3-benzotriazole lead.

BindingDB (2014) · UC San Diego · doi:10.7270/q20003hk

BindingDB Entry 2917: Identification of a new JNK inhibitor targeting the JNK-JIP interaction site.

BindingDB (2008) · UC San Diego · doi:10.7270/q22n50k9

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The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2

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