The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Repair of Endogenous DNA Damage
Abstract
The remarkable stability of genes seemed a puzzlingfeature in the early days of molecular biology. It was evensuggested that new laws of physics might emerge to explain biological paradigms such as the resilience of thegenetic information. The complementary sequences inthe DNA double-helical structure provided a partial answer as to how this stability is retained, but it still tookmore than 10 years after the Watson and Crick 1953model to realize that radiation-damaged residues in DNAcould be corrected by a local excision-repair process. Inretrospect, the early concerns were fully justified; mammalian cellular DNA is a constant target of thermal"noise" in the form of spontaneous hydrolysis at 37ºC,and it is also susceptible to damage caused by active oxygen as well as reactive metabolites and coenzymes. Theresulting lesions are generally removed by the base excision repair (BER) pathway, resulting in short replacementpatches within one of the two DNA strands. Consequently, nonreplicating DNA is not absolutely stable butturns over at a relevant, albeit slow, rate in vivo. This endogenous repair is sufficiently accurate and efficient toexplain the apparent stability of the genetic material...
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“the majority ultimately manifest in the form of single‐strand breaks (SSBs)”
From Mechanisms of DNA damage-mediated neurotoxicity in neurodegenerative disease (2022) · cites this paper as Lindahl & Barnes, 2000
In the citing paper
“reactive oxygen species (ROS), which attack DNA to form oxidized bases and abasic sites”
From Mechanisms of DNA damage-mediated neurotoxicity in neurodegenerative disease (2022) · cites this paper as Lindahl & Barnes, 2000
Citations
Cites
1 retracted
Cooper, P. K., Nouspikel, T. P., Clarkson, S. G., & Leadon, S. A. (1997) · Science · doi:10.1126/science.275.5302.990 · Cited by 306
RetractedRate of depurination of native deoxyribonucleic acid
Lindahl, T. L., & Nyberg, B. (1972) · Biochemistry · doi:10.1021/bi00769a018 · Cited by 1,558
Self-citationLindahl, T. L., & Wood, R. D. (1999) · Science · doi:10.1126/science.286.5446.1897 · Cited by 1,521
Self-citationStructural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
Bruner, S. D., Norman, D. P. G., & Verdine, G. L. (2000) · Nature · doi:10.1038/35002510 · Cited by 972
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
Klungland, A., Rosewell, I., Hollenbach, S., Larsen, E., Daly, G., Epe, B., Seeberg, E., Lindahl, T., & Barnes, D. E. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13300 · Cited by 807
Self-citationMutagenic deamination of cytosine residues in DNA
Duncan, B. K., & Miller, J. H. (1980) · Nature · doi:10.1038/287560a0 · Cited by 792
Klungland, A., & Lindahl, T. (1997) · The EMBO Journal · doi:10.1093/emboj/16.11.3341 · Cited by 789
Self-citationKubota, Y., Nash, R. A., Klungland, A., Schär, P., Barnes, D. E., & Lindahl, T. L. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01056.x · Cited by 776
Self-citationDNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
Mol, C. D., Izumi, T., MITRA, S. P., & Tainer, J. A. (2000) · Nature · doi:10.1038/35000249 · Cited by 764
A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins
Bork, P., Hofmann, K., Bucher, P., Neuwald, A. F., Altschul, S. F., & Koonin, E. V. (1997) · The FASEB Journal · doi:10.1096/fasebj.11.1.9034168 · Cited by 746
Flagged first, then by citations
Research works printed but not linked: 1
- Nakamura J., 1998, Cancer Res., 58, 222
Cited by
Sorted by citations
Items 301–400 of 713
Comparison of Antioxidant Constituents of Agriophyllum squarrosum Seed with Conventional Crop Seeds
Xu, H. Y., Zheng, H., Zhang, H., Zhang, J., & Ma, C. (2018) · Journal of Food Science · doi:10.1111/1750-3841.14159 · Cited by 20
Introduction to the Molecular Biology of the Cell
Marín-García, J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-404599-6.00001-9 · Cited by 20
Nair, R. G., Vasudev, M. M., & Mavathur, R. N. (2021) · Annals of Behavioral Medicine · doi:10.1093/abm/kaab043 · Cited by 19
Arnovitz, S., Mathur, P., Tracy, M., Mohsin, A., Mondal, S., Quandt, J., Hernandez, K. M., Khazaie, K., Dose, M., Emmanuel, A. O., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2201493119 · Cited by 19
Polyzos, A. A., Cheong, A. W. Y., Yoo, J. H., Blagec, L., Toprani, S. M., Nagel, Z. D., & McMurray, C. T. (2024) · Nature Communications · doi:10.1038/s41467-024-51906-5 · Cited by 19
Hosaka, T., Tsuji, H., & Tamaoka, A. (2021) · Processes · doi:10.3390/pr9091667 · Cited by 20
Reactive oxygen species in colorectal cancer adjuvant therapies
Zhang, Y., Hao, M., Yang, X., Zhang, S., Han, J., Wang, Z., & Chen, H. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166922 · Cited by 21
Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation
Sun, F., Ali, N. N., Londoño-Vásquez, D., Simintiras, C. A., Qiao, H., Ortega, M. S., Ağca, Y., Takahashi, M., Rivera, R. M., Kelleher, A. M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53559-w · Cited by 19
Chomchan, R., Siripongvutikorn, S., Maliyam, P., Saibandith, B., & Puttarak, P. (2018) · Foods · doi:10.3390/foods7060081 · Cited by 18
Protection from Ultraviolet Damage and Photocarcinogenesis by Vitamin D Compounds
Silva, W. G. M. D., Abboud, M., Yang, C., Dixon, K. M., Rybchyn, M. S., & Mason, R. S. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-46227-7_12 · Cited by 18
‘Knock down’ of DNA polymerase β by RNA interference: recapitulation of null phenotype
Polosina, Y. Y., Rosenquist, T. A., Grollman, A. P., & Miller, H. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.05.011 · Cited by 18
USP1 in regulation of DNA repair pathways
Aboukheili, A. M. M., & Walden, H. (2025) · DNA repair · doi:10.1016/j.dnarep.2025.103807 · Cited by 17
Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery
Hayman, T. J., & Glazer, P. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312761 · Cited by 19
BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response
Zhao, H., Zhu, M., Dou, G., Zhao, H., Zhu, B., Li, J., Liao, J., & Xu, X. (2014) · Cell Cycle · doi:10.4161/cc.28707 · Cited by 17
Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase
Prakash, A., Moharana, K., Wallace, S. S., & Doublié, S. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw1282 · Cited by 17
The fate of cells undergoing spontaneous DNA damage during development
Miermont, A., Antolović, V., Lenn, T., Nichols, J. M. E., Millward, L. J., & Chubb, J. R. (2019) · Development · doi:10.1242/dev.174268 · Cited by 17
Mathematical Modeling of p53 Pathways
Kim, E., Kim, J.-Y., & Lee, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20205179 · Cited by 17
Gilat, N., Torchinsky, D., Margalit, S., Michaeli, Y., Avraham, S., Sharim, H., Elkoshi, N., Levy, C., Zirkin, S., & Ebenstein, Y. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c01393 · Cited by 16
Bovine Leukemia Virus Infection Affects Host Gene Expression Associated with DNA Mismatch Repair
Bai, L., Hirose, T., Assi, W., Wada, S., Takeshima, S., & Aida, Y. (2020) · Pathogens · doi:10.3390/pathogens9110909 · Cited by 17
Belanger, K. K., Ameredes, B. T., Boldogh, I. R., & Aguilera-Aguirre, L. (2016) · Mediators of Inflammation · doi:10.1155/2016/3762561 · Cited by 19
The effects of metal ion contaminants on the double stranded DNA helix and diseases
Theophanides, T., & Anastassopoulou, J. (2017) · Journal of Environmental Science and Health Part A · doi:10.1080/10934529.2017.1328950 · Cited by 16
Gilat, N., Fridman, D., Sharim, H., Margalit, S., Gassman, N. R., Michaeli, Y., & Ebenstein, Y. (2021) · Biophysical Reports · doi:10.1016/j.bpr.2021.100017 · Cited by 17
Gu, A., Ji, G., Yan, L., & Zhou, Y. (2013) · DNA repair · doi:10.1016/j.dnarep.2013.08.018 · Cited by 16
Buried territories: heterochromatic response to DNA double-strand breaks
Feng, Y.-L., Xiang, J.-F., Kong, N., Cai, X., & Xie, A. (2016) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmw033 · Cited by 16
Nucleostemin reveals a dichotomous nature of genome maintenance in mammary tumor progression
Lin, T., Lin, T.-C., McGrail, D. J., Bhupal, P. K., Ku, Y.-H., Zhang, W., Meng, L., Lin, S., Peng, G., & Tsai, R. Y. L. (2019) · Oncogene · doi:10.1038/s41388-019-0710-0 · Cited by 18
8-Oxoguanine DNA glycosylase1–driven DNA repair—A paradoxical role in lung aging
Germán, P., Saenz, D. N., Szaniszlo, P., Aguilera-Aguirre, L., Pan, L., Hegde, M. L., Bácsi, A., Hajas, G., Radak, Z. O., Ba, X., et al. (2016) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2016.06.009 · Cited by 16
Li, X., Du, Y., Pan, Y.-N., Su, L.-L., Shi, S., Wang, S.-Y., Tang, A., Kim, K., & Kong, D. (2018) · Chemical Communications · doi:10.1039/c8cc08616h · Cited by 15
Mathavarajah, S., VanIderstine, C., Dellaire, G., & Huber, R. J. (2021) · BioEssays · doi:10.1002/bies.202000156 · Cited by 19
Gündoğdu, R., Erdoğan, M. K., Ditsiou, A., Spanswick, V. J., García-Gómez, J. J., Hartley, J. A., Esashi, F., Hergovich, A., & Gómez, V. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.110106 · Cited by 16
Base excision repair accessory factors in senescence avoidance and resistance to treatments
Vickridge, E., Faraco, C. C. F., & Nepveu, A. (2022) · Cancer Drug Resistance · doi:10.20517/cdr.2022.36 · Cited by 15
Cosmic Ionizing Radiation: A DNA Damaging Agent That May Underly Excess Cancer in Flight Crews
Toprani, S. M., Scheibler, C., Mordukhovich, I., McNeely, E., & Nagel, Z. D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147670 · Cited by 19
Kanagavalli, P., Elkaffas, R. A., Mohideen, M. I. H., & Eissa, S. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.138174 · Cited by 15
Ubiquitylation of DNA polymerase λ
Markkanen, E., van Loon, B., Ferrari, E. S., & Hübscher, U. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.03.069 · Cited by 15
Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide
Jamsen, J. A., Sassa, A., Shock, D. D., Beard, W. A., & Wilson, S. H. (2021) · Nature Communications · doi:10.1038/s41467-021-21354-6 · Cited by 15
Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base
Hajas, G., Bácsi, A., Aguilera-Aguirre, L., Germán, P., Radak, Z. O., Sur, S., Hazra, T. K., & Boldogh, I. R. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.11.015 · Cited by 15
The response to the DNA damaging agent methyl methanesulfonate in a fungal plant pathogen
Milo, S., Pareek, M., Delulio, G., Almog, Y., Anand, G., Ma, L., & Covo, S. (2019) · Fungal Biology · doi:10.1016/j.funbio.2019.03.007 · Cited by 15
Rajapakse, A., Suraweera, A., Boucher, D., Naqi, A., O'Byrne, K. J., Richard, D. J., & Croft, L. V. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190430092732 · Cited by 15
Diverse functions of DNA glycosylases processing oxidative base lesions in brain
Scheffler, K., Bjørås, K. Ø., & Bjørås, M. (2019) · DNA repair · doi:10.1016/j.dnarep.2019.102665 · Cited by 13
Impact of Oxidative DNA Damage and the Role of DNA Glycosylases in Neurological Dysfunction
de Sousa, M. M. L., Ye, J., Luna, L., Hildrestrand, G. A., Bjørås, K. Ø., Scheffler, K., & Bjørås, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312924 · Cited by 17
Induction of homologous recombination by site-specific replication stress
Triplett, M. K., Johnson, M. J., & Symington, L. S. (2024) · DNA repair · doi:10.1016/j.dnarep.2024.103753 · Cited by 14
Thakur, M., Agarwal, A., & Muniyappa, K. (2020) · FEBS Journal · doi:10.1111/febs.15465 · Cited by 14
Zilio, N., & Ulrich, H. D. (2020) · FEBS Journal · doi:10.1111/febs.15568 · Cited by 17
Bromodomain proteins: protectors against endogenous DNA damage and facilitators of genome integrity
Lee, S. Y., Kim, J. J., & Miller, K. M. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00673-0 · Cited by 15
Individual Genetic Heterogeneity
Vihinen, M. (2022) · Genes · doi:10.3390/genes13091626 · Cited by 17
The mismatch repair pathway functions normally at a non-AID target in germinal center B cells
Green, B., Belcheva, A., Nepal, R. M., Boulianne, B., & Martín, A. (2011) · Blood · doi:10.1182/blood-2011-03-345991 · Cited by 15
Princz, L. N., Gritenaite, D., & Pfander, B. (2014) · Cell Cycle · doi:10.4161/15384101.2014.989126 · Cited by 16
Altération de la réparation de l’ADN et cancer
Rancoule, C., Vallard, A., Guy, J., Espenel, S., Sauvaigo, S., Rodriguez‐Lafrasse, C., & Magné, N. (2017) · Bulletin du Cancer · doi:10.1016/j.bulcan.2017.09.006 · Cited by 13
Xia, J., Wu, S., Wu, G., & Yang, J. (2022) · Reproductive Biology · doi:10.1016/j.repbio.2022.100679 · Cited by 13
Calabrese, E. J., & Selby, P. B. (2023) · Journal of Occupational and Environmental Hygiene · doi:10.1080/15459624.2023.2252032 · Cited by 13
Origin of Genome Instability and Determinants of Mutational Landscape in Cancer Cells
Mehrotra, S., & Mittra, I. (2020) · Genes · doi:10.3390/genes11091101 · Cited by 14
Effect of Sepatronium Bromide (YM-155) on DNA Double-Strand Breaks Repair in Cancer Cells
Majera, D., & Mistrík, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249431 · Cited by 13
DNA Damage-Induced RNAPII Degradation and Its Consequences in Gene Expression
Muñoz, J. C., Beckerman, I., Choudhary, R., Bouvier, L. A., & Muñoz, M. J. (2022) · Genes · doi:10.3390/genes13111951 · Cited by 13
Reduced nerve growth factor levels in stress-related brain regions of folate-deficient mice
Eckart, S., Hörtnagl, H., Kronenberg, G., Gertz, K. R., Hörster, H., Endres, M., & Hellweg, R. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.04.014 · Cited by 13
Modeling the Study of DNA Damage Responses in Mice
Specks, J., Nieto-Soler, M., Lopez-Contreras, A. J., & Fernández-Capetillo, Ó. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2297-0_21 · Cited by 13
Chu, T., Li, R., Shao, M.-H., Ye, J.-Y., & Han, B. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.100 · Cited by 12
The Role of Oncogenic Tyrosine Kinase NPM-ALK in Genomic Instability
Lobello, C., Bikos, V., Janíková, A., & Pospı́šilová, Š. (2018) · Cancers · doi:10.3390/cancers10030064 · Cited by 13
Deciphering the dynamic code: DNA recognition by transcription factors in the ever-changing genome
Yao, Y. M., Miodownik, I., O’Hagan, M., Jbara, M., & Afek, A. (2024) · Transcription · doi:10.1080/21541264.2024.2379161 · Cited by 12
Athreya, N. B. M., Milenković, O., & Leburton, J. (2020) · npj 2D Materials and Applications · doi:10.1038/s41699-020-00166-0 · Cited by 12
Jung, K., Jung, J., & Park, H. Y. (2021) · Journal of Fungi · doi:10.3390/jof7070566 · Cited by 14
Kim, D. V., Kulishova, L. M., Torgasheva, N. A., Melentyev, V. S., Dianov, G. L., Medvedev, S. P., Zakian, S. M., & Zharkov, D. O. (2021) · PLoS ONE · doi:10.1371/journal.pone.0257473 · Cited by 11
Li, J., Wang, C., Liang, W., Zhang, J., Jiang, C., Liu, Y., Ren, Z., Ci, D., Chang, J., Han, S., et al. (2023) · The Plant Cell · doi:10.1093/plcell/koad056 · Cited by 12
Lawson, T., El‐Kamand, S., Kariawasam, R., Richard, D. J., Cubeddu, L., & Gamsjaeger, R. (2019) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.03.014 · Cited by 12
DNA repair, insulin signaling and sirtuins: at the crossroads between cancer and aging
Mostoslavsky, R. (2008) · Frontiers in bioscience · doi:10.2741/3203 · Cited by 11
Clinical and Mechanistic Implications of R-Loops in Human Leukemias
Lee, S. Y., Miller, K. M., & Kim, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065966 · Cited by 11
Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen
Shell, D. J., Foley, C. A., Wang, Q., Smith, C. M., Guduru, S. K. R., Zeng, H., Dong, A., Norris-Drouin, J. L., Axtman, M., Hardy, P. B., et al. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c01192 · Cited by 12
Aubuchon, L. N., & Verma, P. (2024) · DNA repair · doi:10.1016/j.dnarep.2024.103736 · Cited by 11
Zhang, C.-J., Xu, H., Sui, X., Chen, L., Chen, B., Lv, H., Wang, S., & Wang, X. (2022) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2022.04.012 · Cited by 11
Lin, S., Tian, J., He, Q., Yang, M., Chen, Z., Belogurov, A. A., Li, X., Zhang, F., Liu, Y., & Chen, G. (2022) · Disease Markers · doi:10.1155/2022/7243146 · Cited by 11
Williamson, J., Hughes, C., & Davison, G. W. (2018) · Antioxidants · doi:10.3390/antiox7050070 · Cited by 11
The role of DNA damage as a therapeutic target in autosomal dominant polycystic kidney disease
Zhang, J. Q. J., Saravanabavan, S., Munt, A., Wong, A. T. Y., Harris, D. C. H., Harris, P. C., Wang, Y., & Rangan, G. K. (2019) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2019.6 · Cited by 12
Target-Based Radiosensitization Strategies: Concepts and Companion Animal Model Outlook
Berry, M. R., & Fan, T. M. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.768692 · Cited by 11
Hurwitz, J. L., Jones, B. G., Charpentier, E., & Woodland, D. L. (2017) · Viral Immunology · doi:10.1089/vim.2017.0099 · Cited by 11
Inhibitors against DNA Polymerase I Family of Enzymes: Novel Targets and Opportunities
Kannan, S. R., Gillespie, S. W., Picking, W. L., Picking, W. D., Lorson, C. L., & Singh, K. (2024) · Biology · doi:10.3390/biology13040204 · Cited by 10
Mapping functional elements of the DNA damage response through base editor screens
Pan, Q., Zhang, Z., Xiong, Y., Bao, Y., Chen, T., Xu, P., Liu, Z., Ma, H., Yu, Y., Zhou, Z. L., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.115047 · Cited by 10
A predictive chromatin architecture nexus regulates transcription and DNA damage repair
Bhat, A., Bhan, S., Kabiraj, A., PANDITA, R. K., Ramos, K. S., Nandi, S., Sopori, S., Sarkar, P. S., Dhar, A., Pandita, S., et al. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108300 · Cited by 12
OxiDIP-Seq for Genome-wide Mapping of Damaged DNA Containing 8-Oxo-2'-Deoxyguanosine
Gorini, F., Scala, G., Ambrosio, S., Majello, B., & Amente, S. (2022) · BIO-PROTOCOL · doi:10.21769/bioprotoc.4540 · Cited by 12
Gudiño, R. C., McManus, K. J., & Hombach‐Klonisch, S. (2023) · Cancers · doi:10.3390/cancers15061735 · Cited by 10
Lai, L., Wang, Y., Peng, S., Guo, W., Li, F., & Xu, S. (2022) · Bioengineered · doi:10.1080/21655979.2022.2048985 · Cited by 11
Dong, M., Ouyang, Y., Gao, S.-C., Ma, X., Hou, Y., Schatten, H., Wang, Z., & Sun, Q. (2022) · Development · doi:10.1242/dev.200351 · Cited by 13
Stanio, S., Bacurio, J. H. T., Yang, H., Greenberg, M. M., & Basu, A. K. (2023) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.3c00069 · Cited by 10
In Vitro Lesion Bypass Studies of O4-Alkylthymidines with Human DNA Polymerase η
Williams, N. L., Wang, P., Wu, J., & Wang, Y. (2016) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.5b00509 · Cited by 10
Cell-Cycle Control and DNA-Damage Signaling in Mammals
Gómez, V., & Hergovich, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803309-8.00014-8 · Cited by 12
Upregulation of mNEIL3 inOgg1-null cells is a potential backup mechanism for 8-oxoG repair
Higgs, E. B., Godschalk, R., Langie, S. A. S., van Schooten, F., & Hodges, N. J. (2021) · Mutagenesis · doi:10.1093/mutage/geab038 · Cited by 9
Regenerated Cellulose and Composites for Biomedical Applications
Zamel, D., Khan, A. U., Khan, A. N., Waris, A., Ilyas, M., Ali, A., & Baset, A. (2023) · Engineering materials · doi:10.1007/978-981-99-1655-9_10 · Cited by 9
HR repair pathway plays a crucial role in maintaining neural stem cell fate under irradiation stress
Xu, X. L., An, H., Wu, C., Sang, R., Wu, L., Lou, Y., Yang, X., & Xi, Y. (2023) · Life Science Alliance · doi:10.26508/lsa.202201802 · Cited by 9
Implications of Translesion DNA Synthesis Polymerases on Genomic Stability and Human Health
Venkadakrishnan, J., Lahane, G. P., Dhar, A., Xiao, W., Bhat, K. M., Pandita, T. K., & Bhat, A. (2023) · Molecular and Cellular Biology · doi:10.1080/10985549.2023.2224199 · Cited by 10
Zou, S., Gou, X., & Wen, K. (2023) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2023.5296 · Cited by 10
Targeting TRIP13 for overcoming anticancer drug resistance (Review)
Zhao, L., Ye, S., Jing, S., Gao, Y., & He, T. (2023) · Oncology Reports · doi:10.3892/or.2023.8639 · Cited by 10
SPIN1 facilitates chemoresistance and HR repair by promoting Tip60 binding to H3K9me3
Wang, Y., Li, M., Chen, Y., Jiang, Y., Zhang, Z., Yan, Z., Liu, X., & Wu, C. (2024) · EMBO Reports · doi:10.1038/s44319-024-00219-1 · Cited by 10
Structural insights into DNA double-strand break signaling
Panigrahi, R., & Glover, J. N. M. (2021) · Biochemical Journal · doi:10.1042/bcj20200066 · Cited by 8
Structural insights into the repair mechanism of AGT for methyl-induced DNA damage
Koirala, R. P., Pokhrel, R., Baral, P., Tiwari, P. B., Chapagain, P. P., & Adhikari, N. P. (2021) · Biological Chemistry · doi:10.1515/hsz-2021-0198 · Cited by 9
Nicolai, M. M., Witt, B., Hartwig, A., Schwerdtle, T., & Bornhorst, J. (2021) · Archives of Toxicology · doi:10.1007/s00204-021-03144-7 · Cited by 9
Adhikari, S., Chetram, M. A., Woodrick, J., Mitra, P. S., Manthena, P. V., Khatkar, P., Dakshanamurthy, S., Dixon, M., Karmahapatra, S. K., Nuthalapati, N. K., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.627000 · Cited by 9
Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions
Shanbhag, V., Sachdev, S., Flores, J., Modak, M. J., & Singh, K. (2018) · Biology · doi:10.3390/biology7010005 · Cited by 9
Sites of chromosomal instability in the context of nuclear architecture and function
Pentzold, C., Kokal, M., Pentzold, S., & Weise, A. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03698-2 · Cited by 9
Identification of Nanog as a novel inhibitor of Rad51
Xin, Y., Wang, J., Wu, Y., Li, Q., Dong, M., Liu, C., He, Q., Wang, R., Wang, D., Jiang, S., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04644-9 · Cited by 9
Morón, Á., Martín‐González, A., Díaz, S., Gutiérrez, J. C., & Amaro, F. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.157580 · Cited by 9
Mouse models of DNA polymerases
Menezes, M. R., & Sweasy, J. B. (2012) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21731 · Cited by 9
Spoerri, L., Oo, Z. Y., Larsen, J. E., Haass, N. K., Gabrielli, B. G., & Pavey, S. J. (2014) · Springer eBooks · doi:10.1007/978-94-017-9421-3_3 · Cited by 9
Causes and consequences of DNA double-stranded breaks in cardiovascular disease
Marian, A. J. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05131-9 · Cited by 8
Metadata
- Authors
- LINDAHL, T., & BARNES, D. E.
- ORCID
- LINDAHL, T.
- Venue
- Cold Spring Harbor Symposia on Quantitative Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2000-01-01
- Volume
- 65
- Issue
- 0
- Pages
- 127-134
- ISSN
- 0091-7451 (ISSN-L)
- 1943-4456
- OpenAlex
- W2010677667
- Cited by
- 714
- References
- 60
- Citations by year
- 2026: 22 · 2025: 33 · 2024: 44 · 2023: 41 · 2022: 57 · 2021: 94 · 2020: 57 · 2019: 45 · 2018: 37 · 2017: 52 · 2016: 39 · 2015: 23 · 2014: 37 · 2013: 26 · 2012: 28
- Type
- posted content
- Language
- en
- Open access
- closed
- Locations
- Cold Spring Harbor Symposia on Quantitative Biology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (F31CA260794)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Keywords
- DNA repair, endogenous DNA damage, base excision repair, spontaneous hydrolysis, reactive oxygen species, DNA stability, excision repair
- MeSH terms
- Animals, DNA, DNA Damage, DNA Repair, N-Glycosyl Hydrolases, Mice, Knockout, DNA-Formamidopyrimidine Glycosylase, DNA Glycosylases, Mice, Uracil-DNA Glycosidase
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review