The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Dual Regulation Role of GH3.5 in Salicylic Acid and Auxin Signaling during Arabidopsis-Pseudomonas syringae Interaction
Open accessAbstract
Salicylic acid (SA) plays a central role in plant disease resistance, and emerging evidence indicates that auxin, an essential plant hormone in regulating plant growth and development, is involved in plant disease susceptibility. GH3.5, a member of the GH3 family of early auxin-responsive genes in Arabidopsis (Arabidopsis thaliana), encodes a protein possessing in vitro adenylation activity on both indole-3-acetic acid (IAA) and SA. Here, we show that GH3.5 acts as a bifunctional modulator in both SA and auxin signaling during pathogen infection. Overexpression of the GH3.5 gene in an activation-tagged mutant gh3.5-1D led to elevated accumulation of SA and increased expression of PR-1 in local and systemic tissues in response to avirulent pathogens. In contrast, two T-DNA insertional mutations of GH3.5 partially compromised the systemic acquired resistance associated with diminished PR-1 expression in systemic tissues. The gh3.5-1D mutant also accumulated high levels of free IAA after pathogen infection and impaired different resistance-gene-mediated resistance, which was also observed in the GH3.6 activation-tagged mutant dfl1-D that impacted the auxin pathway, indicating an important role of GH3.5/GH3.6 in disease susceptibility. Furthermore, microarray analysis showed that the SA and auxin pathways were simultaneously augmented in gh3.5-1D after infection with an avirulent pathogen. The SA pathway was amplified by GH3.5 through inducing SA-responsive genes and basal defense components, whereas the auxin pathway was derepressed through up-regulating IAA biosynthesis and down-regulating auxin repressor genes. Taken together, our data reveal novel regulatory functions of GH3.5 in the plant-pathogen interaction.
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Cited by
Salicylic acid, a multifaceted hormone to combat disease
Vlot, A. C., Dempsey, D. A., & Klessig, D. F. (2009) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.050908.135202 · Cited by 2,568
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Self-citationEvolution of Hormone Signaling Networks in Plant Defense
Berens, M. L., Berry, H. M., Mine, A., Argueso, C. T., & Tsuda, K. (2017) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-080516-035544 · Cited by 563
Salicylic Acid and its Function in Plant ImmunityF
An, C., & Mou, Z. (2011) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2011.01043.x · Cited by 517
Hormone (Dis)harmony Moulds Plant Health and Disease
Grant, M. R., & Jones, J. D. G. (2009) · Science · doi:10.1126/science.1173771 · Cited by 434
Metadata
- Authors
- Zhang, Z., Li, Q., Li, Z., Staswick, P. E., Wang, M., Zhu, Y., & He, Z.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-08-17
- Volume
- 145
- Issue
- 2
- Pages
- 450-464
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2102569081
- Cited by
- 323
- References
- 55
- FWCI
- 16.56
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zhang, Z., Li, Q., Li, Z., Staswick, P. E., Wang, M., Zhu, Y., & He, Z. (2007). Dual Regulation Role of GH3.5 in Salicylic Acid and Auxin Signaling during Arabidopsis-Pseudomonas syringae Interaction. Plant Physiology. https://doi.org/10.1104/pp.107.106021
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