The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Nitric Oxide Acts Downstream of Auxin to Trigger Root Ferric-Chelate Reductase Activity in Response to Iron Deficiency in Arabidopsis
Open accessAbstract
In response to iron (Fe) deficiency, dicots employ a reduction-based mechanism by inducing ferric-chelate reductase (FCR) at the root plasma membrane to enhance Fe uptake. However, the signal pathway leading to FCR induction is still unclear. Here, we found that the Fe-deficiency-induced increase of auxin and nitric oxide (NO) levels in wild-type Arabidopsis (Arabidopsis thaliana) was accompanied by up-regulation of root FCR activity and the expression of the basic helix-loop-helix transcription factor (FIT) and the ferric reduction oxidase 2 (FRO2) genes. This was further stimulated by application of exogenous auxin (α-naphthaleneacetic acid) or NO donor (S-nitrosoglutathione [GSNO]), but suppressed by either polar auxin transport inhibition with 1-naphthylphthalamic acid or NO scavenging with 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, tungstate, or Nω-nitro-l-arginine methyl ester hydrochloride. On the other hand, the root FCR activity, NO level, and gene expression of FIT and FRO2 were higher in auxin-overproducing mutant yucca under Fe deficiency, which were sharply restrained by 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide treatment. The opposite response was observed in a basipetal auxin transport impaired mutant aux1-7, which was slightly rescued by exogenous GSNO application. Furthermore, Fe deficiency or α-naphthaleneacetic acid application failed to induce Fe-deficiency responses in noa1 and nial nia2, two mutants with reduced NO synthesis, but root FCR activities in both mutants could be significantly elevated by GSNO. The inability to induce NO burst and FCR activity was further verified in a double mutant yucca noa1 with elevated auxin production and reduced NO accumulation. Therefore, we presented a novel signaling pathway where NO acts downstream of auxin to activate root FCR activity under Fe deficiency in Arabidopsis.
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Cites
IRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
Identification of a Plant Nitric Oxide Synthase Gene Involved in Hormonal Signaling
Guo, F.-Q., Okamoto, M., & Crawford, N. M. (2003) · Science · doi:10.1126/science.1086770 · Cited by 889
Jin, C. W., You, G. Y., He, Y. F., Tang, C., Wu, P., & Zheng, S. J. (2007) · Plant Physiology · doi:10.1104/pp.107.095794 · Cited by 296
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Cited by
Trace metal metabolism in plants
Andresen, E., Peiter, E., & Küpper, H. (2018) · Journal of Experimental Botany · doi:10.1093/jxb/erx465 · Cited by 431
Nitric oxide regulates plant responses to drought, salinity, and heavy metal stress
Nabi, R. B. S., Tayade, R., Hussain, A., Kulkarni, K. P., Imran, Q. M., Mun, B.-G., & Yun, B.-W. (2019) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2019.02.003 · Cited by 401
Molecular mechanisms governing Arabidopsis iron uptake
Brumbarova, T., Bauer, P., & Ivanov, R. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2014.11.004 · Cited by 332
Nitric oxide (NO) and phytohormones crosstalk during early plant development
Sanz, L., Albertos, P., Mateos, I., Sánchez-Vicente, I., Lechón, T., Fernández-Marcos, M., & Lorenzo, O. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv213 · Cited by 297
It’s time to make changes: modulation of root system architecture by nutrient signals
Giehl, R. F. H., Gruber, B. D., & von Wirén, N. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/ert421 · Cited by 295
Metadata
- Authors
- Chen, W. W., Yang, J. L., Qin, C., Jin, C. W., Mo, J. H., Ye, T., & Zheng, S. J.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-08-10
- Volume
- 154
- Issue
- 2
- Pages
- 810-819
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W1993436923
- Cited by
- 373
- References
- 3
- FWCI
- 22.92
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Chen, W. W., Yang, J. L., Qin, C., Jin, C. W., Mo, J. H., Ye, T., & Zheng, S. J. (2010). Nitric Oxide Acts Downstream of Auxin to Trigger Root Ferric-Chelate Reductase Activity in Response to Iron Deficiency in Arabidopsis. Plant Physiology. https://doi.org/10.1104/pp.110.161109
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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