Cited by 431Plant Micronutrient Interactions and EffectsTrace Elements in HealthHeavy Metals in Plants

Trace metal metabolism in plants

Open access
Andresen, Elisa, Peiter, Edgar, Küpper, Hendrik·2018·Journal of Experimental Botany

Abstract

Many trace metals are essential micronutrients, but also potent toxins. Due to natural and anthropogenic causes, vastly different trace metal concentrations occur in various habitats, ranging from deficient to toxic levels. Therefore, one focus of plant research is on the response to trace metals in terms of uptake, transport, sequestration, speciation, physiological use, deficiency, toxicity, and detoxification. In this review, we cover most of these aspects for the essential micronutrients copper, iron, manganese, molybdenum, nickel, and zinc to provide a broader overview than found in other recent reviews, to cross-link aspects of knowledge in this very active research field that are often seen in a separated way. For example, individual processes of metal usage, deficiency, or toxicity often were not mechanistically interconnected. Therefore, this review also aims to stimulate the communication of researchers following different approaches, such as gene expression analysis, biochemistry, or biophysics of metalloproteins. Furthermore, we highlight recent insights, emphasizing data obtained under physiologically and environmentally relevant conditions.

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Crossref · 10.1093/jxb/erx465

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609 of 609 references verified0 citation errors · 0 not checkable

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  • Metal ion transport into vacuoles occurs through CDF (cation diffusion facilitator), MTP (metal tolerance protein), and P1B type ATPase HMA3.

    “Moreover, metal ion transport into vacuoles occurs through CDF (cation diffusion facilitator), MTP (metal tolerance protein), and P1B type ATPase HMA3 (Krämer et al., 2007; Verbruggen et al., 2009b; Andresen et al., 2018).”

    From Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration (2025) · cites this paper as Andresen et al., 2018

    The Manganese section identifies MTP8 as a vacuolar CDF protein that mediates vacuolar Mn storage, and the Zinc section says MTP1 sequesters Zn into vacuoles. These passages support CDF/MTP-mediated transport, but the passages found for HMA proteins do not establish that HMA3 transports metals into vacuoles. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • A great deal of metal ion transport has been explored through studies on ZIP transporters, as they are involved mainly in the uptake of metal ions.

    “A great deal of metal ion transport has been explored through studies on ZIP transporters, as they are involved mainly in the uptake of metal ions (Krämer et al., 2007; Andresen et al., 2018).”

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Cites

1 retracted

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2 of the 611 references couldn’t be matched to a known paper.

Research works printed but not linked: 9

  1. Baccouch S, Chaoui A, Ferjani EE. 2001. Nickel toxicity induces oxidative damage in Zea mays roots. Journal of Plant Nutrition 24, 1085-1097.
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  4. Cramer WA, Zhang H, Yan J, Kurisu G, Smith JL. 2006. Transmembrane traffic in the cytochrome b6f complex. Annual Review of Biochemistry 75, 769-790.
  5. Dewar MJS. 1951. A review of the pi-complex theory. Bulletin de la Socete Chimique de France 18, C71-79.
  6. Fahnestock GW. 1858. Memoranda of the effects of carburetted hydrogen gas upon a collection of exotic plants. Proceedings of the Academy of Natural Sciences of Philadelphia 9-10, 118-134.
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  8. Ignatova LK, Romanova AK. 1992. Participation of carbonic anhydrase in inhibition of photosynthesis in pea protoplasts by CO 2 excess. Russian Journal of Plant Physiology 39, 82-88.
  9. Yoshida H. 1883. Chemistry of lacquer (Urushi). Journal of the Chemical Society, Transactions 43, 472-486.

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Authors
Andresen, E., Peiter, E., & Küpper, H.
Affiliations
  • Czech Academy of Sciences (CZ)
  • Martin Luther University Halle-Wittenberg (DE)
Corresponding author
Küpper, Hendrik
Venue
Journal of Experimental Botany
Published
2018-02-13
Volume
69
Issue
5
Pages
909-954
ISSN
  • 0022-0957 (ISSN-L)
  • 1460-2431
OpenAlex
W2791034768
Cited by
431
References
611
Citations by year
2026: 30 · 2025: 49 · 2024: 58 · 2023: 65 · 2022: 70 · 2021: 87 · 2020: 34 · 2019: 26 · 2018: 11
FWCI
2.02
Type
journal article
Language
en
Open access
Locations
  • Journal of Experimental Botany (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Ministry of Education of the Czech Republic (CZ.02.1.01/0.0/0.0/15_003/0000336)
  • Czech Academy of Sciences (60077344)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Micronutrient Interactions and Effects
  • Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
  • Physical Sciences › Chemistry › Analytical Chemistry › Heavy Metals in Plants
Keywords
trace metal metabolism, micronutrients, metal uptake, metal transport, metal sequestration, metal speciation, metal deficiency, metal toxicity, detoxification, copper, iron, manganese, molybdenum, nickel, zinc, metalloproteins, plant metal homeostasis
MeSH terms
Metals, Plants, Trace Elements

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