The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
FRD3, a Member of the Multidrug and Toxin Efflux Family, Controls Iron Deficiency Responses in Arabidopsis
Open accessAbstract
We present the cloning and characterization of an Arabidopsis gene, FRD3, involved in iron homeostasis. Plants carrying any of the three alleles of frd3 constitutively express three strategy I iron deficiency responses and misexpress a number of iron deficiency-regulated genes. Mutant plants also accumulate approximately twofold excess iron, fourfold excess manganese, and twofold excess zinc in their shoots. frd3-3 was first identified as man1. The FRD3 gene is expressed at detectable levels in roots but not in shoots and is predicted to encode a membrane protein belonging to the multidrug and toxin efflux family. Other members of this family have been implicated in a variety of processes and are likely to transport small organic molecules. The phenotypes of frd3 mutant plants, which are consistent with a defect in either iron deficiency signaling or iron distribution, indicate that FRD3 is an important component of iron homeostasis in Arabidopsis.
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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Towbin, H., Staehelin, T., & Gordon, J. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.9.4350 · Cited by 53,385
Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,221
Floral dip: a simplified method forAgrobacterium‐mediated transformation ofArabidopsis thaliana
Clough, S. J., & Bent, A. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00343.x · Cited by 21,934
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
Predicting Subcellular Localization of Proteins Based on their N-terminal Amino Acid Sequence
Emanuelsson, O., Nielsen, H., Brunak, S., & von Heijne, G. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.3903 · Cited by 4,263
IRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
Self-citationA procedure for mapping Arabidopsis mutations using co‐dominant ecotype‐specific PCR‐based markers
Konieczny, A., & Ausubel, F. M. (1993) · The Plant Journal · doi:10.1046/j.1365-313x.1993.04020403.x · Cited by 1,570
A knowledge base for predicting protein localization sites in eukaryotic cells
Nakai, K., & Kanehisa, M. (1992) · Genomics · doi:10.1016/s0888-7543(05)80111-9 · Cited by 1,511
A novel iron-regulated metal transporter from plants identified by functional expression in yeast.
Eide, D., Broderius, M., Fett, J., & Guerinot, M. L. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5624 · Cited by 1,411
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Cited by
White, P. J., & Broadley, M. R. (2009) · New Phytologist · doi:10.1111/j.1469-8137.2008.02738.x · Cited by 2,178
Zinc in Soils and Crop Nutrition
Sadeghzadeh, B., & Rengel, Z. (2011) · The Molecular and Physiological Basis of Nutrient Use Efficiency in Crops · doi:10.1002/9780470960707.ch16 · Cited by 1,246
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Rout, G. R., & Sahoo, S. (2015) · Reviews in Agricultural Science · doi:10.7831/ras.3.1 · Cited by 958
Localization of Iron in Arabidopsis Seed Requires the Vacuolar Membrane Transporter VIT1
Kim, S. A., Punshon, T., Lanzirotti, A., Li, L., Alonso, J. M., Ecker, J. R., Kaplan, J., & Guerinot, M. L. (2006) · Science · doi:10.1126/science.1132563 · Cited by 687
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Hell, R., & Stephan, U. W. (2003) · Planta · doi:10.1007/s00425-002-0920-4 · Cited by 621
Metadata
- Authors
- Rogers, E. E., & Guerinot, M. L.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-08
- Volume
- 14
- Issue
- 8
- Pages
- 1787-1799
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2051569476
- Cited by
- 337
- References
- 51
- FWCI
- 13.49
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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