The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A novel iron-regulated metal transporter from plants identified by functional expression in yeast.
Open accessAbstract
Iron is an essential nutrient for virtually all organisms. The IRT1 (iron-regulated transporter) gene of the plant Arabidopsis thaliana, encoding a probable Fe(II) transporter, was cloned by functional expression in a yeast strain defective for iron uptake. Yeast expressing IRT1 possess a novel Fe(II) uptake activity that is strongly inhibited by Cd. IRT1 is predicted to be an integral membrane protein with a metal-binding domain. Data base comparisons and Southern blot analysis indicated that IRT1 is a member of a gene family in Arabidopsis. Related sequences were also found in the genomes of rice, yeast, nematodes, and humans. In Arabidopsis, IRT1 is expressed in roots, is induced by iron deficiency, and has altered regulation in plant lines bearing mutations that affect the iron uptake system. These results provide the first molecular insight into iron transport by plants.
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Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669
The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.
Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., & Kaplan, J. (1994) · Cell · doi:10.1016/0092-8674(94)90346-8 · Cited by 670
Self-citationCharacterization of the ferrous iron uptake system of Escherichia coli
Kammler, M., Schön, C., & Hantke, K. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.19.6212-6219.1993 · Cited by 460
Cited by
IRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
Self-citationMolecular mechanisms of plant metal tolerance and homeostasis
Clemens, S. (2001) · Planta · doi:10.1007/s004250000458 · Cited by 1,417
Phylogenetic Relationships within Cation Transporter Families of Arabidopsis
Mäser, P., Thomine, S., Schroeder, J. I., Ward, J. M., Hirschi, K., Sze, H., Talke, I. N., Amtmann, A., Maathuis, F. J. M., Sanders, D., et al. (2001) · Plant Physiology · doi:10.1104/pp.126.4.1646 · Cited by 1,257
Self-citationPhytoremediation of soil metals
Chaney, R. L., Malik, M., Li, Y. M., Brown, S. L., Brewer, E. P., Angle, J. S., & Baker, A. J. (1997) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(97)80004-3 · Cited by 1,254
The ZIP family of metal transporters
Guerinot, M. L. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00138-3 · Cited by 1,200
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Metadata
- Authors
- Eide, D., Broderius, M., Fett, J., & Guerinot, M. L.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1996-05-28
- Volume
- 93
- Issue
- 11
- Pages
- 5624-5628
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2087276505
- Cited by
- 1,411
- References
- 3
- FWCI
- 36.63
- Type
- journal article
- Language
- en
- Open access
- green
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- Eide, D., Broderius, M., Fett, J., & Guerinot, M. L. (1996). A novel iron-regulated metal transporter from plants identified by functional expression in yeast. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.93.11.5624
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