The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Maintenance of DNA Methylation during the Arabidopsis Life Cycle Is Essential for Parental Imprinting
Open accessAbstract
Imprinted genes are expressed predominantly from either their paternal or their maternal allele. To date, all imprinted genes identified in plants are expressed in the endosperm. In Arabidopsis thaliana, maternal imprinting has been clearly demonstrated for the Polycomb group gene MEDEA (MEA) and for FWA. Direct repeats upstream of FWA are subject to DNA methylation. However, it is still not clear to what extent similar cis-acting elements may be part of a conserved molecular mechanism controlling maternally imprinted genes. In this work, we show that the Polycomb group gene FERTILIZATION-INDEPENDENT SEED2 (FIS2) is imprinted. Maintenance of FIS2 imprinting depends on DNA methylation, whereas loss of DNA methylation does not affect MEA imprinting. DNA methylation targets a small region upstream of FIS2 distinct from the target of DNA methylation associated with FWA. We show that FWA and FIS2 imprinting requires the maintenance of DNA methylation throughout the plant life cycle, including male gametogenesis and endosperm development. Our data thus demonstrate that parental genomic imprinting in plants depends on diverse cis-elements and mechanisms dependent or independent of DNA methylation. We propose that imprinting has evolved under constraints linked to the evolution of plant reproduction and not by the selection of a specific molecular mechanism.
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Cites
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Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
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Vernalization requires epigenetic silencing of FLC by histone methylation
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Cited by
Zilberman, D., Gehring, M., Tran, R. K., Ballinger, T., & Henikoff, S. (2007) · Nature Genetics · doi:10.1038/ng1929 · Cited by 1,367
Epigenetic inheritance in plants
Henderson, I. R., & Jacobsen, S. E. (2007) · Nature · doi:10.1038/nature05917 · Cited by 835
Active DNA Demethylation Mediated by DNA Glycosylases
Zhu, J.-K. (2009) · Annual Review of Genetics · doi:10.1146/annurev-genet-102108-134205 · Cited by 745
A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
Lowder, L. G., Zhang, D., Baltes, N. J., Paul, J. W., Tang, X., Zheng, X., Voytas, D. F., Hsieh, T.-F., Zhang, Y., & Qi, Y. (2015) · Plant Physiology · doi:10.1104/pp.15.00636 · Cited by 707
Extensive Demethylation of Repetitive Elements During Seed Development Underlies Gene Imprinting
Gehring, M., Bubb, K. L., & Henikoff, S. (2009) · Science · doi:10.1126/science.1171609 · Cited by 571
Metadata
- Authors
- Jullien, P. E., Kinoshita, T., Ohad, N., & Berger, F.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-04-28
- Volume
- 18
- Issue
- 6
- Pages
- 1360-1372
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2143279767
- Cited by
- 286
- References
- 49
- FWCI
- 14.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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