The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.
Phospholipase Dα1 and Phosphatidic Acid Regulate NADPH Oxidase Activity and Production of Reactive Oxygen Species in ABA-Mediated Stomatal Closure in Arabidopsis
Open accessAbstract
We determined the role of Phospholipase Dα1 (PLDα1) and its lipid product phosphatidic acid (PA) in abscisic acid (ABA)-induced production of reactive oxygen species (ROS) in Arabidopsis thaliana guard cells. The pldα1 mutant failed to produce ROS in guard cells in response to ABA. ABA stimulated NADPH oxidase activity in wild-type guard cells but not in pldα1 cells, whereas PA stimulated NADPH oxidase activity in both genotypes. PA bound to recombinant Arabidopsis NADPH oxidase RbohD (respiratory burst oxidase homolog D) and RbohF. The PA binding motifs were identified, and mutation of the Arg residues 149, 150, 156, and 157 in RbohD resulted in the loss of PA binding and the loss of PA activation of RbohD. The rbohD mutant expressing non-PA-binding RbohD was compromised in ABA-mediated ROS production and stomatal closure. Furthermore, ABA-induced production of nitric oxide (NO) was impaired in pldα1 guard cells. Disruption of PA binding to ABI1 protein phosphatase 2C did not affect ABA-induced production of ROS or NO, but the PA–ABI1 interaction was required for stomatal closure induced by ABA, H2O2, or NO. Thus, PA is as a central lipid signaling molecule that links different components in the ABA signaling network in guard cells.
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Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins
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Regulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors
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Reactive oxygen species produced by NADPH oxidase regulate plant cell growth
Foreman, J., Demidchik, V., Bothwell, J. H. F., Mylona, P., Miedema, H., Torres, M. A., Linstead, P., Costa, S., Brownlee, C., Jones, J. D. G., et al. (2003) · Nature · doi:10.1038/nature01485 · Cited by 2,239
Abscisic Acid Signaling in Seeds and Seedlings
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Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells
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NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis
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Harb, A., Krishnan, A., Ambavaram, M. M. R., & Pereira, A. (2010) · Plant Physiology · doi:10.1104/pp.110.161752 · Cited by 747
Regulation of the NADPH Oxidase RBOHD During Plant Immunity
Kadota, Y., Shirasu, K., & Zipfel, C. (2015) · Plant and Cell Physiology · doi:10.1093/pcp/pcv063 · Cited by 641
Spreading the news: subcellular and organellar reactive oxygen species production and signalling
Mignolet-Spruyt, L., Xu, E., Idänheimo, N., Hoeberichts, F. A., Mühlenbock, P., Brosché, M., Van Breusegem, F., & Kangasjärvi, J. (2016) · Journal of Experimental Botany · doi:10.1093/jxb/erw080 · Cited by 459
Molecular, cellular, and physiological responses to phosphatidic acid formation in plants
Testerink, C., & Munnik, T. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err079 · Cited by 409
Metadata
- Authors
- Zhang, Y., Zhu, H., Zhang, Q., Li, M., Yan, M., Wang, R., Wang, L., Welti, R., Zhang, W., & Wang, X.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-08-01
- Volume
- 21
- Issue
- 8
- Pages
- 2357-2377
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2164534658
- Cited by
- 580
- References
- 89
- FWCI
- 30.60
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zhang, Y., Zhu, H., Zhang, Q., Li, M., Yan, M., Wang, R., Wang, L., Welti, R., Zhang, W., & Wang, X. (2009). Phospholipase Dα1 and Phosphatidic Acid Regulate NADPH Oxidase Activity and Production of Reactive Oxygen Species in ABA-Mediated Stomatal Closure in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.108.062992
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