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Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

Open access
Park, Sang-Youl, Fung, Pauline, Nishimura, Noriyuki, Jensen, Davin R., Fujii, Hiroaki, Zhao, Yang, Lumba, Shelley, Santiago, Julia, Rodrigues, Americo, Chow, Tsz-fung F., Alfred, Simon E., Bonetta, Dario, Finkelstein, Ruth, Provart, Nicholas J., Desveaux, Darrell, Rodriguez, Pedro L., McCourt, Peter, Zhu, Jian-Kang, Schroeder, Julian I., Volkman, Brian F., Cutler, Sean R.·2009·Science

Abstract

ABA Receptor Rumbled?: The plant hormone abscisic acid (ABA) is critical for normal development and for mediating plant responses to stressful environmental conditions. Now, two papers present analyses of candidate ABA receptors (see the news story by Pennisi ). Ma et al. (p. 1064; published online 30 April) and Park et al. (p. 1068, published online 30 April) used independent strategies to search for proteins that physically interact with ABI family phosphatase components of the ABA response signaling pathway. Both groups identified different members of the same family of proteins, which appear to interact with ABI proteins to form a heterocomplex that can act as the ABA receptor. The variety of both families suggests that the ABA receptor may not be one entity, but rather a class of closely related complexes, which may explain previous difficulties in establishing its identity.

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Metadata

Authors
Park, S.-Y., Fung, P., Nishimura, N., Jensen, D. R., Fujii, H., Zhao, Y., Lumba, S., Santiago, J., Rodrigues, A., Chow, T.-F. F., Alfred, S. E., Bonetta, D., Finkelstein, R., Provart, N. J., Desveaux, D., Rodriguez, P. L., McCourt, P., Zhu, J.-K., Schroeder, J. I., Volkman, B. F., & Cutler, S. R.
Venue
Science
Published
2009-05-22
Volume
324
Issue
5930
Pages
1068-1071
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2078929441
Cited by
2,974
References
0
FWCI
157.93
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins. https://app.cochat.ai/papers/10.1126/science.1173041
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Park, S.-Y., Fung, P., Nishimura, N., Jensen, D. R., Fujii, H., Zhao, Y., Lumba, S., Santiago, J., Rodrigues, A., Chow, T.-F. F., Alfred, S. E., Bonetta, D., Finkelstein, R., Provart, N. J., Desveaux, D., Rodriguez, P. L., McCourt, P., Zhu, J.-K., Schroeder, J. I., . . . Cutler, S. R. (2009). Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins. Science. https://doi.org/10.1126/science.1173041

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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