DWARF27, an Iron-Containing Protein Required for the Biosynthesis of Strigolactones, Regulates Rice Tiller Bud Outgrowth
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Tillering in rice (Oryza sativa) is one of the most important agronomic traits that determine grain yields. Previous studies on rice tillering mutants have shown that the outgrowth of tiller buds in rice is regulated by a carotenoid-derived MAX/RMS/D (more axillary branching) pathway, which may be conserved in higher plants. Strigolactones, a group of terpenoid lactones, have been recently identified as products of the MAX/RMS/D pathway that inhibits axillary bud outgrowth. We report here the molecular genetic characterization of d27, a classic rice mutant exhibiting increased tillers and reduced plant height. D27 encodes a novel iron-containing protein that localizes in chloroplasts and is expressed mainly in vascular cells of shoots and roots. The phenotype of d27 is correlated with enhanced polar auxin transport. The phenotypes of the d27 d10 double mutant are similar to those of d10, a mutant defective in the ortholog of MAX4/RMS1 in rice. In addition, 2′-epi-5-deoxystrigol, an identified strigolactone in root exudates of rice seedlings, was undetectable in d27, and the phenotypes of d27 could be rescued by supplementation with GR24, a synthetic strigolactone analog. Our results demonstrate that D27 is involved in the MAX/RMS/D pathway, in which D27 acts as a new member participating in the biosynthesis of strigolactones.
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Novel roles for SL in plant architecture other than shoot branching have been suggested for dwarfism and root architecture.
“Novel roles for SL in plant architecture, other than shoot branching, have been recently suggested for dwarfism (Lin et al., 2009) and root architecture (Koltai et al., 2009;Kapulnik et al., 2011;Ruyter-Spira et al., 2011).”
From The Pea TCP Transcription Factor PsBRC1 Acts Downstream of Strigolactones to Control Shoot Branching (2012) · cites this paper as Lin et al., 2009
SL biosynthesis starts from carotenoid precursors via D27.
“SL biosynthesis starts from carotenoid precursors via the action of the all-trans/9-cis-β-carotene isomerase D27 in rice and AtD27 in Arabidopsis (Lin et al., 2009; Waters et al., 2012).”
From Shaping plant architecture (2015) · cites this paper as Lin et al., 2009
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“The other proposes that strigolactones function as secondary messengers of auxin that repress the bud outgrowth directly (Beveridge et al., 2000; Brewer et al., 2009; Ferguson and Beveridge, 2009).”
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“outgrowth of tiller buds of the wild type was significantly promoted, which is consistent with the long-established concept that too little auxin transport also leads to an increased shoot branching (Chatfield et al., 2000).”
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- Authors
- Lin, H., Wang, R., Qian, Q., Yan, M., Meng, X., Fu, Z., Yan, C., Jiang, B., Su, Z., Li, J., & Wang, Y.
- Affiliations
- Chinese Academy of Sciences (CN)
- Chinese Academy of Agricultural Sciences (CN)
- National Center for Plant Gene Research (Beijing), Beijing 100101, China
- China Agricultural University (CN)
- Corresponding author
- Wang, Yonghong
- ORCID
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-05-01
- Volume
- 21
- Issue
- 5
- Pages
- 1512-1525
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- PMC
- PMC2700539
- OpenAlex
- W2100828771
- Cited by
- 670
- References
- 10
- Citations by year
- 2026: 37 · 2025: 25 · 2024: 55 · 2023: 42 · 2022: 45 · 2021: 42 · 2020: 44 · 2019: 51 · 2018: 43 · 2017: 36 · 2016: 30 · 2015: 39 · 2014: 43 · 2013: 45 · 2012: 32
- FWCI
- 37.64
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- The Plant Cell (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Iowa Research Online (University of Iowa) (submittedVersion)
- Funders
- National Natural Science Foundation of China (90817108, 30830009)
- Chinese Academy of Sciences
- Hokkaido University
- Peking University
- Stony Brook University
- Institute of Hydrobiology
- Institute of Biophysics, Chinese Academy of Sciences
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- strigolactone biosynthesis, rice tillering, iron-containing proteins, polar auxin transport, GR24, plant height
- MeSH terms
- Biological Transport, Chloroplasts, Cloning, Molecular, Indoleacetic Acids, Iron, Lactones, Molecular Sequence Data, Phenotype, Plant Proteins, Oryza, Terpenes
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