The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
The Arabidopsis GTL1 Transcription Factor Regulates Water Use Efficiency and Drought Tolerance by Modulating Stomatal Density via Transrepression of SDD1
Open accessAbstract
A goal of modern agriculture is to improve plant drought tolerance and production per amount of water used, referred to as water use efficiency (WUE). Although stomatal density has been linked to WUE, the causal molecular mechanisms have yet to be determined. Arabidopsis thaliana GT-2 LIKE 1 (GTL1) loss-of-function mutations result in increased water deficit tolerance and higher integrated WUE by reducing daytime transpiration without a demonstrable reduction in biomass accumulation. gtl1 plants had higher instantaneous WUE that was attributable to ~25% lower transpiration and stomatal conductance but equivalent CO2 assimilation. Lower transpiration was associated with higher STOMATAL DENSITY AND DISTRIBUTION1 (SDD1) expression and an ~25% reduction in abaxial stomatal density. GTL1 expression occurred in abaxial epidermal cells where the protein was localized to the nucleus, and its expression was downregulated by water stress. Chromatin immunoprecipitation analysis indicated that GTL1 interacts with a region of the SDD1 promoter that contains a GT3 box. An electrophoretic mobility shift assay was used to determine that the GT3 box is necessary for the interaction between GTL1 and the SDD1 promoter. These results establish that GTL1 negatively regulates WUE by modulating stomatal density via transrepression of SDD1.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Stomatal Conductance and Photosynthesis
Farquhar, G. D., & Sharkey, T. D. (1982) · Annual Review of Plant Physiology · doi:10.1146/annurev.pp.33.060182.001533 · Cited by 4,159
Understanding plant responses to drought—from genes to the whole plant.
Chaves, M. M., Maroco, J. P., & Pereira, J. S. (2003) · Functional Plant Biology · doi:10.1071/fp02076 · Cited by 3,845
Plant Physiological Ecology: Field methods and instrumentation
(2000) · Springer eBooks · doi:10.1007/978-94-010-9013-1 · Cited by 3,294
Network motifs: theory and experimental approaches
Alon, U. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2102 · Cited by 3,279
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., & Shinozaki, K. (1998) · The Plant Cell · doi:10.1105/tpc.10.8.1391 · Cited by 3,044
GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
Zimmermann, P., Hirsch-Hoffmann, M., Hennig, L., & Gruissem, W. (2004) · Plant Physiology · doi:10.1104/pp.104.046367 · Cited by 2,462
The role of stomata in sensing and driving environmental change
Hetherington, A. M., & Woodward, F. I. (2003) · Nature · doi:10.1038/nature01843 · Cited by 2,399
Agrobacterium-mediated transformation of Arabidopsis thaliana using the floral dip method
Zhang, X., Henriques, R., Lin, S.-S., Niu, Q.-W., & Chua, N.-H. (2006) · Nature Protocols · doi:10.1038/nprot.2006.97 · Cited by 2,335
Stomatal Control of Transpiration: Scaling Up from Leaf to Region
Jarvis, P. G., & McNaughton, K. G. (1986) · Advances in Ecological Research · doi:10.1016/s0065-2504(08)60119-1 · Cited by 1,995
Lambers, H., Chapin, F. S., & Pons, T. L. (1998) · Springer eBooks · doi:10.1007/978-1-4757-2855-2 · Cited by 1,769
Cited by
Impact of stomatal density and morphology on water-use efficiency in a changing world
Bertolino, L. T., Caine, R. S., & Gray, J. E. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00225 · Cited by 706
Sodium (Na+) homeostasis and salt tolerance of plants
Hasegawa, P. M. (2013) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2013.03.001 · Cited by 498
Self-citationOsakabe, Y., Yamaguchi-Shinozaki, K., Shinozaki, K., & Tran, L.-S. P. (2013) · Journal of Experimental Botany · doi:10.1093/jxb/ers354 · Cited by 384
Kulkarni, M., Soolanayakanahally, R., Ogawa, S., Uga, Y., Selvaraj, M. G., & Kagale, S. (2017) · Frontiers in Chemistry · doi:10.3389/fchem.2017.00106 · Cited by 230
Loss of CDKC ; 2 increases both cell division and drought tolerance in Arabidopsis thaliana
Zhao, L., Li, Y., Xie, Q., & Wu, Y. (2017) · The Plant Journal · doi:10.1111/tpj.13609 · Cited by 50
Metadata
- Authors
- Yoo, C. Y., Pence, H. E., Jin, J. B., Miura, K., Gosney, M. J., Hasegawa, P. M., & Mickelbart, M. V.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-12-01
- Volume
- 22
- Issue
- 12
- Pages
- 4128-4141
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2164425190
- Cited by
- 353
- References
- 65
- FWCI
- 13.46
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Arabidopsis GTL1 Transcription Factor Regulates Water Use Efficiency and Drought Tolerance by Modulating Stomatal Density via Transrepression of SDD1. https://app.cochat.ai/papers/10.1105/tpc.110.078691
- The paper
- Yoo, C. Y., Pence, H. E., Jin, J. B., Miura, K., Gosney, M. J., Hasegawa, P. M., & Mickelbart, M. V. (2011). The Arabidopsis GTL1 Transcription Factor Regulates Water Use Efficiency and Drought Tolerance by Modulating Stomatal Density via Transrepression of SDD1. The Plant Cell. https://doi.org/10.1105/tpc.110.078691
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
