The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
A Plasma Membrane Receptor Kinase, GHR1, Mediates Abscisic Acid- and Hydrogen Peroxide-Regulated Stomatal Movement in Arabidopsis
Open accessAbstract
The plant hormone abscisic acid (ABA) regulates stomatal movement under drought stress, and this regulation requires hydrogen peroxide (H2O2). We isolated GUARD CELL HYDROGEN PEROXIDE-RESISTANT1 (GHR1), which encodes a receptor-like kinase localized on the plasma membrane in Arabidopsis thaliana. ghr1 mutants were defective ABA and H2O2 induction of stomatal closure. Genetic analysis indicates that GHR1 is a critical early component in ABA signaling. The ghr1 mutation impaired ABA- and H2O2-regulated activation of S-type anion currents in guard cells. Furthermore, GHR1 physically interacted with, phosphorylated, and activated the S-type anion channel SLOW ANION CHANNEL-ASSOCIATED1 when coexpressed in Xenopus laevis oocytes, and this activation was inhibited by ABA-INSENSITIVE2 (ABI2) but not ABI1. Our study identifies a critical component in ABA and H2O2 signaling that is involved in stomatal movement and resolves a long-standing mystery about the differential functions of ABI1 and ABI2 in this process.
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Cites
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Cited by
Spreading the news: subcellular and organellar reactive oxygen species production and signalling
Mignolet-Spruyt, L., Xu, E., Idänheimo, N., Hoeberichts, F. A., Mühlenbock, P., Brosché, M., Van Breusegem, F., & Kangasjärvi, J. (2016) · Journal of Experimental Botany · doi:10.1093/jxb/erw080 · Cited by 459
Osakabe, Y., Yamaguchi-Shinozaki, K., Shinozaki, K., & Tran, L.-S. P. (2013) · Journal of Experimental Botany · doi:10.1093/jxb/ers354 · Cited by 384
Closing gaps: linking elements that control stomatal movement
Kollist, H., Nuhkat, M., & Roelfsema, M. R. G. (2014) · New Phytologist · doi:10.1111/nph.12832 · Cited by 357
Stomatal Defense a Decade Later
Melotto, M., Zhang, L., Oblessuc, P. R., & He, S. Y. (2017) · Plant Physiology · doi:10.1104/pp.16.01853 · Cited by 339
Degradation of the ABA co-receptor ABI1 by PUB12/13 U-box E3 ligases
Kong, L., Cheng, J., Zhu, Y., Ding, Y., Meng, J., Chen, Z., Xie, Q., Guo, Y., Li, J., Yang, S., et al. (2015) · Nature Communications · doi:10.1038/ncomms9630 · Cited by 316
Self-citation
Metadata
- Authors
- Hua, D., Wang, C., He, J., Liao, H., Duan, Y., Zhu, Z., Guo, Y., Chen, Z., & Gong, Z.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-06
- Volume
- 24
- Issue
- 6
- Pages
- 2546-2561
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2115296684
- Cited by
- 417
- References
- 71
- FWCI
- 21.21
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Hua, D., Wang, C., He, J., Liao, H., Duan, Y., Zhu, Z., Guo, Y., Chen, Z., & Gong, Z. (2012). A Plasma Membrane Receptor Kinase, GHR1, Mediates Abscisic Acid- and Hydrogen Peroxide-Regulated Stomatal Movement in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.112.100107
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