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Cited by 935

The DOI matches its Crossref record; 206 of the 206 references it cites were found in a registry or an index.

Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs

Open access
Rogers, K., Chen, X.·2013·The Plant Cell

Abstract

MicroRNAs (miRNAs) are small RNAs that control gene expression through silencing of target mRNAs. Mature miRNAs are processed from primary miRNA transcripts by the endonuclease activity of the DICER-LIKE1 (DCL1) protein complex. Mechanisms exist that allow the DCL1 complex to precisely excise the miRNA from its precursor. Our understanding of miRNA biogenesis, particularly its intersection with transcription and other aspects of RNA metabolism such as splicing, is still evolving. Mature miRNAs are incorporated into an ARGONAUTE (AGO) effector complex competent for target gene silencing but are also subjected to turnover through a degradation mechanism that is beginning to be understood. The mechanisms of miRNA target silencing in plants are no longer limited to AGO-catalyzed slicing, and the contribution of translational inhibition is increasingly appreciated. Here, we review the mechanisms underlying the biogenesis, turnover, and activities of plant miRNAs.

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Crossref · 10.1105/tpc.113.113159

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Metadata

Authors
Rogers, K., & Chen, X.
Venue
The Plant Cell
Published
2013-07-01
Volume
25
Issue
7
Pages
2383-2399
ISSN
  • 1040-4651 (ISSN-L)
  • 1532-298X
OpenAlex
W2042325491
Cited by
935
References
206
FWCI
83.03
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs. https://app.cochat.ai/papers/10.1105/tpc.113.113159
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Rogers, K., & Chen, X. (2013). Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs. The Plant Cell. https://doi.org/10.1105/tpc.113.113159

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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