NAS-Unet: Neural Architecture Search for Medical Image Segmentation
Open accessAbstract
Neural architecture search (NAS) has significant progress in improving the accuracy of image classification. Recently, some works attempt to extend NAS to image segmentation which shows preliminary feasibility. However, all of them focus on searching architecture for semantic segmentation in natural scenes. In this paper, we design three types of primitive operation set on search space to automatically find two cell architecture DownSC and UpSC for semantic image segmentation especially medical image segmentation. Inspired by the U-net architecture and its variants successfully applied to various medical image segmentation, we propose NAS-Unet which is stacked by the same number of DownSC and UpSC on a U-like backbone network. The architectures of DownSC and UpSC updated simultaneously by a differential architecture strategy during the search stage. We demonstrate the good segmentation results of the proposed method on Promise12, Chaos, and ultrasound nerve datasets, which collected by magnetic resonance imaging, computed tomography, and ultrasound, respectively. Without any pretraining, our architecture searched on PASCAL VOC2012, attains better performances and much fewer parameters (about 0.8M) than U-net and one of its variants when evaluated on the above three types of medical image datasets.
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NAS-Unet explored differentiable NAS strategies on a U-shaped backbone for medical image segmentation.
“NAS-Unet, proposed in 2019, explored differentiable NAS strategies (e.g., DARTS/ProxylessNAS-style methods) on a U-shaped backbone for medical image segmentation [10].”
From Optimizing Neural Network Architecture for Medical Image Segmentation Using Monte Carlo Tree Search (2026) · cites this paper as [10]
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MethodEvaluation of prostate segmentation algorithms for mri: The promise12 challenge
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U-Net and Its Variants for Medical Image Segmentation: A Review of Theory and Applications
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“Among the existing research works in this area, NAS-UNet [111] is based on the design of three types of primitive operation set on search space to automatically find two cell architectures (DownSC and UpSC) for semantic segmen-”
MethodC2FNAS: Coarse-to-Fine Neural Architecture Search for 3D Medical Image Segmentation
Yu, Q., Yang, D., Roth, H. R., Bai, Y., Zhang, Y., Yuille, A., & Xu, D. (2020) · IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings - IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings · doi:10.1109/cvpr42600.2020.00418 · Cited by 153 · see citing works
Wei, J., Zhu, G., Fan, Z., et al. (2021) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2021.3111679 · Cited by 137 · see citing works
A bird's-eye view of deep learning in bioimage analysis
Meijering, E. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.08.003 · Cited by 126 · see citing works
“First successful applications have recently been reported in medical imaging [252,280,281], suggesting NAS holds great potential also for bioimage analysis.”
BackgroundAdaEn-Net: An ensemble of adaptive 2D–3D Fully Convolutional Networks for medical image segmentation
Baldeon-Calisto, M., & Lai-Yuen, S. K. (2020) · Neural Networks · doi:10.1016/j.neunet.2020.03.007 · Cited by 138 · see citing works
DiNTS: Differentiable Neural Network Topology Search for 3D Medical Image Segmentation
He, Y., Yang, D., Roth, H. R., Zhao, C., & Xu, D. (2021) · IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings - IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings · doi:10.1109/cvpr46437.2021.00578 · Cited by 130 · see citing works
“In medical image segmentation, NAS-UNet [40], V-NAS [48] and Kim et al [15] search cells and apply it to a U-Net-like topology.”
MethodHalf-UNet: A Simplified U-Net Architecture for Medical Image Segmentation
Lu, H., She, Y., Tie, J., & Xu, S. (2022) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2022.911679 · Cited by 130 · see citing works
“Weng et al. (2019) proposed NAS-UNet, using three types of primitive operation sets and search space to automatically find two cell architectures, DownSC and UpSC, for medical image segmentation, which attains better performance and uses much fewer parameters (about 0.8 M) than standard U-Net.”
MethodInfluentialAutomated Machine Learning for Healthcare and Clinical Notes Analysis
Mustafa, A., & Azghadi, M. R. (2021) · Computers · doi:10.3390/computers10020024 · Cited by 131 · see citing works
“Images Cancer [12] [61] Covid-19 [62] Generic [44] [46] [63] Liver Injury [64] Pachychoroid [65] Structured Tabular Alzheimer [14] BioSignature [13] Brain Age [58] Brain Tumor [59] Cardiac [25] Diabetes [66] Generic [37] [11] Metabolic [60] As the table shows, most of the unstructured data is…”
BackgroundMethodA hybrid deep segmentation network for fundus vessels via deep-learning framework
Yang, L., Wang, H., Zeng, Q., Liu, Y., & Bian, G. (2021) · Neurocomputing · doi:10.1016/j.neucom.2021.03.085 · Cited by 127 · see citing works
Jiang, H., Shen, F., Gao, F., & Han, W. (2021) · Pattern Recognition · doi:10.1016/j.patcog.2021.107825 · Cited by 120 · see citing works
“Besides, several NAS based 3D medical image segmentation methods are proposed in [20, 21].”
MethodAdvancements in Deep Learning for B-Mode Ultrasound Segmentation: A Comprehensive Review
Ansari, M. Y., Mangalote, I. A. C., Meher, P. K., Aboumarzouk, O. M., Al-Ansari, A. A., Halabi, O., & Dakua, S. P. (2024) · IEEE Transactions on Emerging Topics in Computational Intelligence · doi:10.1109/tetci.2024.3377676 · Cited by 116 · see citing works
“Weng et al. [134] utilize the idea of neural architecture search (NAS) for finding the optimal combination of layers within a convolutional block of a U-Net architecture to segment MRI, CT, and US images.”
BackgroundZhang, J., Qin, Q., Ye, Q., & Ruan, T. (2023) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2022.106516 · Cited by 111 · see citing works
MFSNet: A multi focus segmentation network for skin lesion segmentation
Basak, H., Kundu, R., & Sarkar, R. (2022) · Pattern Recognition · doi:10.1016/j.patcog.2022.108673 · Cited by 112 · see citing works
“Weng et al. [51] proposed another modification in the U-Net backbone by incorporating neural architecture search (NAS), thereby improving the segmentation performance significantly.”
BackgroundFung, D. L. X., Liu, Q., Zammit, J., Leung, C. K.-S., & Hu, P. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-02992-2 · Cited by 104 · see citing works
Flexible sensors and machine learning for heart monitoring
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Hussain, T., & Shouno, H. (2024) · IEEE Access · doi:10.1109/access.2024.3374108 · Cited by 91 · see citing works
“Skip connections have been proposed to eliminate these gaps [1], [22].”
BackgroundWeight-Sharing Neural Architecture Search: A Battle to Shrink the Optimization Gap
Xie, L., Chen, X., Bi, K., Wei, L., Xu, Y., Wang, L., Chen, Z., Xiao, A., Chang, J., Zhang, X., et al. (2021) · ACM Computing Surveys · doi:10.1145/3473330 · Cited by 108 · see citing works
“though searching for efficient blocks is also verified useful [152], [266], [276].”
BackgroundGuo, L., Lei, B., Chen, W., Du, J., Frangi, A. F., Qin, J., Zhao, C., Shi, P., Xia, B., & Wang, T. (2021) · Medical Image Analysis · doi:10.1016/j.media.2021.102042 · Cited by 85 · see citing works
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Sorghum Panicle Detection and Counting Using Unmanned Aerial System Images and Deep Learning
Lin, Z., & Guo, W. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.534853 · Cited by 79 · see citing works
“The spatial dimensions of the feature maps were halved and the number of feature maps was doubled repeatedly through the down-sampling layer (Guan et al., 2019; Weng et al., 2019).”
BackgroundJiao, Y., Yang, K., Song, D., & Tao, D. (2022) · IEEE Transactions on Network Science and Engineering · doi:10.1109/tnse.2022.3148276 · Cited by 73 · see citing works
“Previous works about AutoML mostly focus on the domains of computer vision and natural language processing, including object detection [35, 36], semantic segmentation [37, 38], translation [39], and sequence labeling [40].”
BackgroundArtificial intelligence in musculoskeletal ultrasound imaging
Shin, Y., Yang, J., Lee, Y. H., & Kim, S. J. (2020) · ULTRASONOGRAPHY · doi:10.14366/usg.20080 · Cited by 73 · see citing works
“[61] employed neural architecture search, which used autoML algorithms that returned the best neural network through the sampling of building blocks to create an end-to-end structure, and achieved encouraging results (mean intersection over union, 0.”
MethodResUNet+: A New Convolutional and Attention Block-Based Approach for Brain Tumor Segmentation
Metlek, S., & Çetıner, H. (2023) · IEEE Access · doi:10.1109/access.2023.3294179 · Cited by 73 · see citing works
“In order to eliminate these semantic gaps, some improvements have been suggested in the literature by using different skip connections [21], [22].”
BackgroundHuang, G., Zhu, J., Li, J., Wang, Z., Cheng, L., Liu, L., Li, H., & Zhou, J. (2020) · IEEE Access · doi:10.1109/access.2020.3007719 · Cited by 71 · see citing works
Neural Architecture Search for Skin Lesion Classification
Kwasigroch, A., Grochowski, M., & Mikołajczyk, A. (2020) · IEEE Access · doi:10.1109/access.2020.2964424 · Cited by 67 · see citing works
BB-UNet: U-Net With Bounding Box Prior
Jurdi, R. E., Petitjean, C., Honeiné, P., & Abdallah, F. (2020) · IEEE Journal of Selected Topics in Signal Processing · doi:10.1109/jstsp.2020.3001502 · Cited by 67 · see citing works
“emerged in order to increase model performance given different tasks [6], [7].”
BackgroundShuvo, M. B., Ahommed, R., Reza, S., & Hashem, M. M. A. (2021) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2021.102959 · Cited by 62 · see citing works
Techniques for Automated Machine Learning
Chen, Y., Song, Q., & Hu, X. (2021) · ACM SIGKDD Explorations Newsletter · doi:10.1145/3447556.3447567 · Cited by 62 · see citing works
A Comprehensive Survey on Hardware-Aware Neural Architecture SearchPreprint
Benmeziane, H., Maghraoui, K. E., Ouarnoughi, H., Niar, S., Wistuba, M., & Wang, N. (2021) · arXiv (Cornell University) · doi:10.48550/arxiv.2101.09336 · Cited by 78 · see citing works
“…[90], [136], [121], [137], [61], [62], [67], [68], [70], [71], [95], [96], [97], [102], [99], [107], [108], [109], [113] MCU [123], [63], [111], [138], [23], [89] Mobile Devices [47], [53], [23], [57], [59], [66], [18], [60], [87], [85], [86], [110], [84], [80], [99] ASICs [72], [118], [119],…”
BackgroundTesting and quality validation for AI software–perspectives, issues, and practices
Tao, C., Gao, J., & Wang, T. (2019) · IEEE Access · doi:10.1109/access.2019.2937107 · Cited by 60 · see citing works
VesNet-RL: Simulation-Based Reinforcement Learning for Real-World US Probe Navigation
Bi, Y., Jiang, Z., Gao, Y., Wendler, T., Karlas, A., & Navab, N. (2022) · IEEE Robotics and Automation Letters · doi:10.1109/lra.2022.3176112 · Cited by 62 · see citing works
MS-NAS: Multi-scale Neural Architecture Search for Medical Image Segmentation
Yan, X., Jiang, W., Shi, Y., & Zhuo, C. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-59710-8_38 · Cited by 58 · see citing works
LAEDNet: A Lightweight Attention Encoder–Decoder Network for ultrasound medical image segmentation
Zhou, Q., Wang, Q., Bao, Y., et al. (2022) · Computers & Electrical Engineering · doi:10.1016/j.compeleceng.2022.107777 · Cited by 58 · see citing works
Baldeon-Calisto, M., & Lai-Yuen, S. K. (2021) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2021.102154 · Cited by 54 · see citing works
2D to 3D Evolutionary Deep Convolutional Neural Networks for Medical Image Segmentation
Hassanzadeh, T., Essam, D., & Sarker, R. A. (2020) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2020.3035555 · Cited by 55 · see citing works
“Besides, NAS U–Net [36] obtained almost the similar results of the manual–designed networks, because, NAS U–Net also uses a unique network structure for segmentation.”
MethodResultInfluentialAhmad, I., Xia, Y., Cui, H., & Islam, Z. U. (2022) · Expert Systems with Applications · doi:10.1016/j.eswa.2022.118945 · Cited by 54 · see citing works
LSPnet: A 2D Localization-oriented Spacecraft Pose Estimation Neural Network
Garcia, A., Musallam, M. A., Gaudillière, V., Ghorbel, E., Ismaeil, K. A., Perez, M. D., & Aouada, D. (2021) · IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW) · doi:10.1109/cvprw53098.2021.00233 · Cited by 53 · see citing works
A Multi-Attention and Depthwise Separable Convolution Network for Medical Image Segmentation
Zhou, Y., Kang, X., Ren, F., Lu, H., Nakagawa, S., & Xiao, S. (2023) · Neurocomputing · doi:10.1016/j.neucom.2023.126970 · Cited by 53 · see citing works
Comprehensive Review: Machine and Deep Learning in Brain Stroke Diagnosis
Fernandes, J. N. D., Cardoso, V. E. M., Comesaña-Campos, A., & Pinheira, A. G. (2024) · Sensors · doi:10.3390/s24134355 · Cited by 58 · see citing works
“This field of work already presents relevant literature, as can be seen in the works of Zhu et al. [118] and Weng et al. [119].”
MethodAutomated Design of Deep Neural Networks
Talbi, E. (2021) · ACM Computing Surveys · doi:10.1145/3439730 · Cited by 57 · see citing works
“Then, the problem consists in finding the optimal architecture at the outer-level using this fixed set of inner-level cells [49, 181, 197, 215] (Figure 6).”
BackgroundMethodMonchot, P., Coquelin, L., Guerroudj, K., Feltin, N., Delvallée, A., Crouzier, L., & Fischer, N. (2021) · Nanomaterials · doi:10.3390/nano11040968 · Cited by 51 · see citing works
“While semantic methods are adapted to numerous cases of study such as medical images [14,15], mineral characterization [16] or meteorology [17], they can not be applied to our images, where TiO2 particles tend to agglomerate.”
MethodExploring applications of blockchain in healthcare: road map and future directions
Singh, Y., Jabbar, M. A., Shandilya, S. K., Вовк, О., & Hnatiuk, Y. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1229386 · Cited by 60 · see citing works
Chen, S., Yang, H., Fu, J., Mei, W.-J., Ren, S., Liu, Y., Zhu, Z., Liu, L., Li, H., & Chen, H. (2019) · IEEE Access · doi:10.1109/access.2019.2923760 · Cited by 49 · see citing works
Adaptive segmentation model for liver CT images based on neural network and level set method
Shu, X., Yang, Y., & Wu, B. (2021) · Neurocomputing · doi:10.1016/j.neucom.2021.01.081 · Cited by 48 · see citing works
DSRNA: Differentiable Search of Robust Neural Architectures
Hosseini, R., Yang, X., & Xie, P. (2021) · IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings - IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings · doi:10.1109/cvpr46437.2021.00613 · Cited by 48 · see citing works
Imaging through diffuse media using multi-mode vortex beams and deep learning
Balasubramaniam, G. M., Biton, N., & Arnon, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-05358-w · Cited by 48 · see citing works
“Although initially, this architecture was used for a segmentation problem, recent studies have shown that this architecture is very efficient for the required restoration 16,53,54 .”
MethodGuo, X., Zhang, N., Guo, J., et al. (2019) · Medical Physics · doi:10.1002/mp.13865 · Cited by 47 · see citing works
Kendrick, J., Francis, R. J., Hassan, G. M., Rowshanfarzad, P., Ong, J. S. L., & Ebert, M. A. (2022) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-022-05927-1 · Cited by 46 · see citing works
M-Net: An encoder-decoder architecture for medical image analysis using ensemble learning
Sreelakshmi, S., Malu, G., Sherly, E., et al. (2023) · Results in Engineering · doi:10.1016/j.rineng.2023.100927 · Cited by 44 · see citing works
Xiao, X., Zhang, J., Shao, Y., Liu, J., Shi, K., He, C., & Kong, D. (2025) · Sensors · doi:10.3390/s25082361 · Cited by 46 · see citing works
“Weng et al. [46], inspired by the U-net architecture and its successful variants applied to various medical image segmentation tasks, proposed NAS-Unet.”
Semantic Segmentation on Panoramic Dental X-Ray Images Using U-Net Architectures
Zannah, R., Bashar, M., Mushfiq, R. B., Chakrabarty, A., Hossain, S., & Jung, Y. J. (2024) · IEEE Access · doi:10.1109/access.2024.3380027 · Cited by 47 · see citing works
“In the paper [37], inspired by U-Net architectures, the author introduces the Neural Architecture Search (NAS) system, aligning it with U-Net models.”
MethodOyelade, O. N., & Ezugwu, A. E.-S. (2021) · Scientific Reports · doi:10.1038/s41598-021-98978-7 · Cited by 43 · see citing works
“Studies have shown that DL architectures, convolutional neural networks (CNN) specifically engineered using these approaches, have outperformed the handcrafted architectures applied to some problems 4–6 .”
BackgroundAutomatic void content assessment of composite laminates using a machine-learning approach
Machado, J., Tavares, J., Camanho, P., & Correia, N. (2022) · Composite structures · doi:10.1016/j.compstruct.2022.115383 · Cited by 39 · see citing works
Intraoperative Glioma Grading Using Neural Architecture Search and Multi-Modal Imaging
Xiao, A., Shen, B., Shi, X., Zhang, Z., Zhang, Z., Tian, J., Ji, N., & Hu, Z. (2022) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2022.3166129 · Cited by 41 · see citing works
“Some recent studies in the medical field have also used NAS and achieved remarkable results in the segmentation of MRI and CT images [40]–[42].”
Yu, C., Wang, Y., Tang, C., Feng, W., & Lv, J. (2023) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2023.107579 · Cited by 44 · see citing works
Radiomics for Identification and Prediction in Metastatic Prostate Cancer: A Review of Studies
Kendrick, J., Francis, R. J., Hassan, G. M., Rowshanfarzad, P., Jeraj, R., Kasisi, C., Rusanov, B., & Ebert, M. A. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.771787 · Cited by 41 · see citing works
Deep learning for gastroscopic images: computer-aided techniques for clinicians
Jin, Z., Gan, T., Wang, P., Fu, Z., Zhang, C., Yan, Q., Zheng, X., Liang, X., & Ye, X. (2022) · BioMedical Engineering OnLine · doi:10.1186/s12938-022-00979-8 · Cited by 40 · see citing works
“For example, NASUNet [125], AutoDeepLab [126], MS-NAS [127], and BiX-NAS [128] have achieved SOTA performance on medical image segmentation.”
BackgroundPocketNet: A Smaller Neural Network for Medical Image Analysis
Celaya, A., Actor, J., Rajarajeswari, M., Gates, E. D. H., Chung, C. D., Schellingerhout, D., Rivière, B. M., & Fuentes, D. (2022) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2022.3224873 · Cited by 40 · see citing works
Visual geometry Group-UNet: Deep learning ultrasonic image reconstruction for curved parts
Mei, Y., Jin, H., Yu, B., et al. (2021) · The Journal of the Acoustical Society of America · doi:10.1121/10.0004827 · Cited by 39 · see citing works
Tutorial on the Use of Deep Learning in Diffuse Optical Tomography
Balasubramaniam, G. M., Wiesel, B., Biton, N., Kumar, R., Kupferman, J., & Arnon, S. (2022) · Electronics · doi:10.3390/electronics11030305 · Cited by 40 · see citing works
Ruan, D., Han, J., Yan, J., & Gühmann, C. (2023) · Scientific Reports · doi:10.1038/s41598-023-31532-9 · Cited by 39 · see citing works
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Multi-Scale Network for Thoracic Organs Segmentation
Khalil, M. I., Tehsin, S., Humayun, M., Jhanjhi, N. Z., & AlZain, M. A. (2021) · Computers, materials & continua/Computers, materials & continua (Print) · doi:10.32604/cmc.2022.020561 · Cited by 38 · see citing works
“Segmentation segments of the image into cohesive regions, clustering techniques may be extended to subdivision by removing the overall features of the object to efficiently distinguish ROI from the object context [5].”
Yu, Z., Lee, F., & Chen, Q. (2023) · Applied Intelligence · doi:10.1007/s10489-023-04570-z · Cited by 38 · see citing works
Deep Ice Layer Tracking and Thickness Estimation using Fully Convolutional Networks
Varshney, D., Rahnemoonfar, M., Yari, M., et al. (2020) · IEEE International Conference on Big Data (BigData) · doi:10.1109/bigdata50022.2020.9378070 · Cited by 37 · see citing works
“strategy, combined with data augmentation, turned out to be useful in biomedical image segmentation, especially for detecting tissue deformations. The success of UNet in biomedical images [31], [42], [43] led to its application and improvement for other domains such as remote sensing [44], [45] and autonomous driving…”
MethodLu, Z., Xia, W., Huang, Y., et al. (2022) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2022.3219286 · Cited by 37 · see citing works
“In the field of medical imaging, most works were proposed for image segmentation and classification [13, 17, 35, 55, 59, 61].”
BackgroundMethodInfluentialYOLO‐UNet Architecture for Detecting and Segmenting the Localized MRI Brain Tumor Image
Iriawan, N., Pravitasari, A. A., Nuraini, U. S., et al. (2024) · Applied Computational Intelligence and Soft Computing · doi:10.1155/2024/3819801 · Cited by 36 · see citing works
Learning deep morphological networks with neural architecture search
Hu, Y., Belkhir, N., Angulo, J., et al. (2022) · Pattern Recognition · doi:10.1016/j.patcog.2022.108893 · Cited by 36 · see citing works
“An alternative approach focuses on automatically finding the network architecture design using Neural Architecture Search (NAS) methods Liu et al. (2019a); Luo et al. (2019); Liu et al. (2018); Pham et al. (2018); Weng et al. (2019) in lieu of manual design.”
MethodMukasa, P., Wakholi, C., Faqeerzada, M. A., Amanah, H. Z., Kim, H., Joshi, R., Suh, H. K., Kim, G., Lee, H., Kim, M. S., et al. (2022) · Computers and Electronics in Agriculture · doi:10.1016/j.compag.2022.106799 · Cited by 36 · see citing works
Multi-Scale Fusion U-Net for the Segmentation of Breast Lesions
Li, J., Cheng, L., Xia, T., Ni, H., & Li, J. (2021) · IEEE Access · doi:10.1109/access.2021.3117578 · Cited by 36 · see citing works
Efficient Automation of Neural Network Design: A Survey on Differentiable Neural Architecture Search
Heuillet, A., Nasser, A., Arioui, H., et al. (2024) · ACM Computing Surveys · doi:10.1145/3665138 · Cited by 35 · see citing works
Discretization-aware architecture search
Tian, Y., Liu, C., Xie, L., Jiao, J., & Ye, Q. (2021) · Pattern Recognition · doi:10.1016/j.patcog.2021.108186 · Cited by 33 · see citing works
Cheng, P., Myronenko, A., Hatamizadeh, A., Nath, V., Siddiquee, M. M. R., He, Y., Xu, D., Chellappa, R., & Yang, D. (2022) · IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings - IEEE Computer Society Conference on Computer Vision and Pattern Recognition/Proceedings · doi:10.1109/cvpr52688.2022.02008 · Cited by 35 · see citing works
“Early attempts [21, 37, 44, 47] build on the prior architecture of U-Net, and modify edge operations and connections while preserving the overall U-shape structure.”
BackgroundWhen Neural Architecture Search Meets Hardware Implementation: from Hardware Awareness to Co-Design
Zhang, X., Jiang, W., Shi, Y., & Hu, J. (2019) · IEEE Computer Society Annual Symposium on VLSI · doi:10.1109/isvlsi.2019.00014 · Cited by 37 · see citing works
“Most recently, neural architecture search techniques are extended for more complicated tasks, such as Image Segmentation [14, 43].”
BackgroundZhang, B., Rahmatullah, B., Wang, S. L., Zhang, G., Wang, H., & Ebrahim, N. A. (2021) · Journal of Applied Clinical Medical Physics · doi:10.1002/acm2.13394 · Cited by 35 · see citing works
BiX-NAS: Searching Efficient Bi-directional Architecture for Medical Image Segmentation
Wang, X., Xiang, T., Zhang, C., et al. (2021) · Lecture notes in computer science · doi:10.1007/978-3-030-87193-2_22 · Cited by 34 · see citing works
“Similar to the nuclei segmentation, Table 2 indicates that BiX-Net achieves the best performance of all classes among state-of-the-art NAS searched networks [16,9,18] with much lower computational complexity.”
MethodCombining contrastive learning and shape awareness for semi-supervised medical image segmentation
Chen, Y., Chen, F., & Huang, C. (2023) · Expert Systems with Applications · doi:10.1016/j.eswa.2023.122567 · Cited by 33 · see citing works
Low-Memory CNNs Enabling Real-Time Ultrasound Segmentation Towards Mobile Deployment
Vaze, S., Xie, W., & Namburete, A. I. L. (2020) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2019.2961264 · Cited by 33 · see citing works
“and familiar taskwhich has beenwidely studied in the ultrasound analysis literature since its publication [13], [14].”
BackgroundYing, W., Zheng, Q., Wu, Y., Yang, K., Zhou, Z., Chen, J., & Ye, Z. (2023) · Applied Soft Computing · doi:10.1016/j.asoc.2023.110869 · Cited by 32 · see citing works
DEGAS: differentiable efficient generator search
Doveh, S., & Giryes, R. (2021) · Neural Computing and Applications · doi:10.1007/s00521-021-06309-8 · Cited by 33 · see citing works
“These include semantic image segmentation [28], medical image segmentation [48], volumetric medical image segmentation [52], object detection [34], and active learning [14].”
BackgroundMulti-scale conv-attention U-Net for medical image segmentation
Pan, P., Zhang, C., Sun, J.-B., & Guo, L. (2025) · Scientific Reports · doi:10.1038/s41598-025-96101-8 · Cited by 48 · see citing works
“Due to its powerful segmentation performance, U-net has been widely used as an indispensable tool in the field of medical image processing and has achieved remarkable success in numerous 2D semantic segmentation tasks 12–14 .”
SliceMamba With Neural Architecture Search for Medical Image Segmentation
Fan, C., Yu, H., Huang, Y., Wang, L., Yang, Z., & Jia, X. (2025) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2025.3564381 · Cited by 30 · see citing works
“Additionally, Weng et al. [49] introduced NAS-UNet, which utilizes neural architecture search (NAS) to discover optimal model architectures tailored to different datasets automatically.”
AutoSegNet: An Automated Neural Network for Image Segmentation
Xu, Z., Zuo, S., Lam, E. Y. M., Lee, B., & Chen, N. (2020) · IEEE Access · doi:10.1109/access.2020.2995367 · Cited by 30 · see citing works
“NAS-Unet [24] searches a U-like backbone network for medical image segmentation, and V-NAS [25] formulates the structure learning as differentiable neural architecture search, allowing the network to choose among 2D, 3D or Pseudo-3D (P3D) convolutions at each layer.”
MethodWu, J., Liu, W., Li, C., et al. (2023) · Neural Computing and Applications · doi:10.1007/s00521-023-09284-4 · Cited by 30 · see citing works
Varshney, D., Rahnemoonfar, M., Yari, M., et al. (2021) · Remote Sensing · doi:10.3390/rs13142707 · Cited by 29 · see citing works
“UNet’s success in processing biomedical images [32,33] inspired its application in remote sensing [34,35] and autonomous driving [36], among other domains.”
BackgroundYu, Y., Chen, S., & Wei, H. (2022) · Flow Measurement and Instrumentation · doi:10.1016/j.flowmeasinst.2022.102300 · Cited by 28 · see citing works
Multiclass Segmentation of Concrete Surface Damages Using U-Net and DeepLabV3+
Hadinata, P. N., Simanta, D., Eddy, L., & Nagai, K. (2023) · Applied Sciences · doi:10.3390/app13042398 · Cited by 29 · see citing works
- Authors
- Weng, Y., Zhou, T., Li, Y., & Qiu, X.
- Affiliations
- Minzu University of China (CN)
- Yangzhou University (CN)
- Shandong University of Traditional Chinese Medicine (CN)
- Venue
- IEEE Access
- Published
- 2019
- Volume
- 7
- Pages
- 44247-44257
- ISSN
- 2169-3536 (ISSN-L)
- OpenAlex
- W2927980542
- Semantic Scholar
- 90d06dca4796e3b0bd75161beb1a1d9264170769
- Cited by
- 487
- References
- 54
- Citations by year
- 2026: 21 · 2025: 54 · 2024: 89 · 2023: 97 · 2022: 72 · 2021: 87 · 2020: 57 · 2019: 10
- FWCI
- 25.30
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- IEEE Access (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Natural Science Foundation of China (61772575)
- National Key R&D Program of China (2017YFB1402101)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Advanced Neural Network Applications
- Physical Sciences › Computer Science › Artificial Intelligence › Domain Adaptation and Few-Shot Learning
- Keywords
- neural architecture search, medical image segmentation, semantic segmentation, U-Net, magnetic resonance imaging, CT
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