A Smartphone-Based Tool for Assessing Parkinsonian Hand Tremor
Abstract
The aim of this study is to propose a practical smartphone-based tool to accurately assess upper limb tremor in Parkinson's disease (PD) patients. The tool uses signals from the phone's accelerometer and gyroscope (as the phone is held or mounted on a subject's hand) to compute a set of metrics which can be used to quantify a patient's tremor symptoms. In a small-scale clinical study with 25 PD patients and 20 age-matched healthy volunteers, we combined our metrics with machine learning techniques to correctly classify 82% of the patients and 90% of the healthy volunteers, which is high compared to similar studies. The proposed method could be effective in assisting physicians in the clinic, or to remotely evaluate the patient's condition and communicate the results to the physician. Our tool is low cost, platform independent, noninvasive, and requires no expertise to use. It is also well matched to the standard clinical examination for PD and can keep the patient "connected" to his physician on a daily basis. Finally, it can facilitate the creation of anonymous profiles for PD patients, aiding further research on the effectiveness of medication or other overlooked aspects of patients' lives.
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Previous studies have shown that smartphone accelerometers are comparable to laboratory accelerometers in the assessment and classification of tremors.
“In fact, previous studies have shown that smartphone accelerometers are comparable to laboratory accelerometers in the assessment and classification of tremors [6–10]”
From Differential diagnosis between Parkinson's disease and essential tremor using the smartphone's accelerometer (2017) · cites this paper as [7]
Cites
The Smartphone in Medicine: A Review of Current and Potential Use Among Physicians and Students
Ozdalga, E., Ozdalga, A., & Ahuja, N. (2012) · Journal of Medical Internet Research · doi:10.2196/jmir.1994 · Cited by 654 · see citing works
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Artificial intelligence for assisting diagnostics and assessment of Parkinson’s disease—A review
Belić, M., Bobić, V., Badža, M., Šolaja, N., Đurić-Jovičić, M., & Kostić, V. S. (2019) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2019.105442 · Cited by 194 · see citing works
Reinertsen, E., & Clifford, G. D. (2018) · Physiological Measurement · doi:10.1088/1361-6579/aabf64 · Cited by 136 · see citing works
Barrantes, S., Sánchez Egea, A. J., González Rojas, H. A., Martí, M. J., Compta, Y., Valldeoriola, F., Simo Mezquita, E., Tolosa, E., & Valls-Solè, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183843 · Cited by 106 · see citing works
Iakovakis, D., Hadjidimitriou, S., Charisis, V., Bostantzopoulou, S., Katsarou, Z., & Hadjileontiadis, L. J. (2018) · Scientific Reports · doi:10.1038/s41598-018-25999-0 · Cited by 92 · see citing works
Buechi, R., Faes, L., Bachmann, L. M., Thiel, M. A., Bodmer, N. S., Schmid, M. K., Job, O., & Lienhard, K. R. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-018280 · Cited by 50 · see citing works
- Authors
- Kostikis, N., Hristu-Varsakelis, D., Arnaoutoglou, M., & Kotsavasiloglou, C.
- Affiliations
- University of Macedonia (GR)
- Aristotle University of Thessaloniki (GR)
- Venue
- IEEE Journal of Biomedical and Health Informatics
- Published
- 2015-11
- Volume
- 19
- Issue
- 6
- Pages
- 1835-1842
- ISSN
- 2168-2194 (ISSN-L)
- 2168-2208
- OpenAlex
- W1918508591
- Cited by
- 139
- References
- 1
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 12 · 2023: 17 · 2022: 14 · 2021: 16 · 2020: 20 · 2019: 14 · 2018: 16 · 2017: 13 · 2016: 5
- FWCI
- 9.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Journal of Biomedical and Health Informatics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Context-Aware Activity Recognition Systems
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Keywords
- Parkinson's disease, hand tremor, smartphone sensors, accelerometer, gyroscope, tremor quantification, machine learning classification, remote patient monitoring
- MeSH terms
- Smartphone, Machine Learning, Aged, Aged, 80 and over, Female, Hand, Humans, Male, Middle Aged, Monitoring, Physiologic, Parkinson Disease, Tremor, Cluster Analysis, Accelerometry, Mobile Applications
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