The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Design Considerations of Silicon Nanowire Biosensors
Abstract
Biosensors based on silicon nanowires (Si-NWs) promise highly sensitive dynamic label-free electrical detection of biomolecules. Despite the tremendous potential and promising experimental results, the fundamental mechanism of electrical sensing of biomolecules and the design considerations of NW sensors remain poorly understood. In this paper, we discuss the prospects and challenges of biomolecule detection using Si-NW biosensors as a function of device parameters, fluidic environment, charge polarity of biomolecules, etc., and refer to experimental results in literature to support the nonintuitive predictions wherever possible. Our results indicate that the design of Si nanobiosensor is nontrivial and as such, only careful optimization supported by numerical simulation would ensure optimal sensor performance.
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Cites
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Label-free immunodetection with CMOS-compatible semiconducting nanowires
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Cited by
Subthreshold Regime has the Optimal Sensitivity for Nanowire FET Biosensors
Gao, X. P. A., Zheng, G., & Lieber, C. M. (2010) · Nano Letters · doi:10.1021/nl9034219 · Cited by 571
Nernst Limit in Dual-Gated Si-Nanowire FET Sensors
Knopfmacher, O., Tarasov, A., Fu, W., Wipf, M., Niesen, B., Calame, M., & Schönenberger, C. (2010) · Nano Letters · doi:10.1021/nl100892y · Cited by 353
Stress Biomarkers in Biological Fluids and Their Point-of-Use Detection
Steckl, A. J., & Ray, P. (2018) · ACS Sensors · doi:10.1021/acssensors.8b00726 · Cited by 319
Effect of Nanowire Number, Diameter, and Doping Density on Nano-FET Biosensor Sensitivity
Li, J., Zhang, Y., To, S., You, L., & Sun, Y. (2011) · ACS Nano · doi:10.1021/nn202182p · Cited by 138
Label-free DNA detection with a nanogap embedded complementary metal oxide semiconductor
Kim, C.-H., Jung, C., Lee, K.-B., Park, H. G., & Choi, Y.-K. (2011) · Nanotechnology · doi:10.1088/0957-4484/22/13/135502 · Cited by 103
Metadata
- Authors
- Nair, P. R., & Alam, M. A.
- Venue
- IEEE Transactions on Electron Devices
- Published
- 2007
- Volume
- 54
- Issue
- 12
- Pages
- 3400-3408
- ISSN
- 0018-9383 (ISSN-L)
- OpenAlex
- W2151385252
- Cited by
- 316
- References
- 28
- FWCI
- 9.14
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
