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Cited by 871

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

PET-CT image registration in the chest using free-form deformations

Mattes, D., Haynor, D.R., Vesselle, H., Lewellen, T.K., Eubank, W.·2003·IEEE Transactions on Medical Imaging

Abstract

We have implemented and validated an algorithm for three-dimensional positron emission tomography transmission-to-computed tomography registration in the chest, using mutual information as a similarity criterion. Inherent differences in the two imaging protocols produce significant nonrigid motion between the two acquisitions. A rigid body deformation combined with localized cubic B-splines is used to capture this motion. The deformation is defined on a regular grid and is parameterized by potentially several thousand coefficients. Together with a spline-based continuous representation of images and Parzen histogram estimates, our deformation model allows closed-form expressions for the criterion and its gradient. A limited-memory quasi-Newton optimization algorithm is used in a hierarchical multiresolution framework to automatically align the images. To characterize the performance of the method, 27 scans from patients involved in routine lung cancer staging were used in a validation study. The registrations were assessed visually by two expert observers in specific anatomic locations using a split window validation technique. The visually reported errors are in the 0- to 6-mm range and the average computation time is 100 min on a moderate-performance workstation.

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Metadata

Authors
Mattes, D., Haynor, D. R., Vesselle, H., Lewellen, T. K., & Eubank, W.
Venue
IEEE Transactions on Medical Imaging
Published
2003-01
Volume
22
Issue
1
Pages
120-128
ISSN
0278-0062 (ISSN-L)
OpenAlex
W2157380596
Cited by
871
References
3
FWCI
28.05
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: PET-CT image registration in the chest using free-form deformations. https://app.cochat.ai/papers/10.1109/tmi.2003.809072
The paper
Mattes, D., Haynor, D. R., Vesselle, H., Lewellen, T. K., & Eubank, W. (2003). PET-CT image registration in the chest using free-form deformations. IEEE Transactions on Medical Imaging. https://doi.org/10.1109/tmi.2003.809072

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