Model-Heterogeneous Semi-Supervised Federated Learning for Medical Image Segmentation
Abstract
Medical image segmentation is crucial in clinical diagnosis, helping physicians identify and analyze medical conditions. However, this task is often accompanied by challenges like sensitive data, privacy concerns, and expensive annotations. Current research focuses on personalized collaborative training of medical segmentation systems, ignoring that obtaining segmentation annotations is time-consuming and laborious. Achieving a perfect balance between annotation cost and segmentation performance while ensuring local model personalization has become a valuable direction. Therefore, this study introduces a novel Model-Heterogeneous Semi-Supervised Federated (HSSF) Learning framework. It proposes Regularity Condensation and Regularity Fusion to transfer autonomously selective knowledge to ensure the personalization between sites. In addition, to efficiently utilize unlabeled data and reduce the annotation burden, it proposes a Self-Assessment (SA) module and a Reliable Pseudo-Label Generation (RPG) module. The SA module generates self-assessment confidence in real-time based on model performance, and the RPG module generates reliable pseudo-label based on SA confidence. We evaluate our model separately on the Skin Lesion and Polyp Lesion datasets. The results show that our model performs better than other methods characterized by heterogeneity. Moreover, it exhibits highly commendable performance even in homogeneous designs, most notably in region-based metrics. The full range of resources can be readily accessed through the designated repository located at HSSF(github.com) on the platform of GitHub.
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Federated learning presents a viable solution for leveraging multimodal data from multiple health care institutions without the need to share the actual data, thus maintaining patient privacy.
“In addition, federated learning presents a viable solution for leveraging multimodal data from multiple health care institutions without the need to share the actual data, thus maintaining patient privacy [152-156].”
From Multimodal Large Language Models in Health Care: Applications, Challenges, and Future Outlook. (2024) · cites this paper as [155]
Federated learning techniques enable M-LLMs to be trained on decentralized data sources without the need to transfer sensitive or private information to a central location, thereby preserving data privacy and security.
“One of these measures is the implementation of federated learning techniques [153,155,156] to enable M-LLMs to be trained on decentralized data sources without the need to transfer sensitive or private information to a central location, thereby preserving data privacy and security.”
From Multimodal Large Language Models in Health Care: Applications, Challenges, and Future Outlook. (2024) · cites this paper as [155]
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- Authors
- Ma, Y., Wang, J., Yang, J., & Wang, L.
- Affiliations
- Xiamen University (CN)
- Venue
- IEEE Transactions on Medical Imaging
- Published
- 2024-05
- Volume
- 43
- Issue
- 5
- Pages
- 1804-1815
- ISSN
- 0278-0062 (ISSN-L)
- 1558-254X
- OpenAlex
- W4390480840
- Cited by
- 55
- References
- 51
- Citations by year
- 2026: 28 · 2025: 23 · 2024: 4
- FWCI
- 7.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- IEEE Transactions on Medical Imaging (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Science and Technology of the People’s Republic of China (STI2030-Major Projects2021ZD0201900)
- National Natural Science Foundation of China (62371409)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Physical Sciences › Computer Science › Artificial Intelligence › Domain Adaptation and Few-Shot Learning
- Physical Sciences › Computer Science › Artificial Intelligence › Privacy-Preserving Technologies in Data
- Keywords
- semi-supervised federated learning, model heterogeneity, medical image segmentation, annotation cost reduction, pseudo-label generation, skin lesion segmentation, polyp segmentation, privacy-preserving collaborative learning
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