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Cited by 37Fungal and yeast genetics researchFungal Biology and ApplicationsBiofuel production and bioconversion

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Production of yeast cell wall polysaccharides‐β‐glucan and chitin by using food waste substrates: Biosynthesis, production, extraction, and purification methods

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Günal‐Köroğlu, Deniz, Karabulut, Gulsah, Mohammadian, Fariddudin, Can Karaca, Aslı, Capanoglu, Esra, Esatbeyoglu, Tuba·2025·Comprehensive Reviews in Food Science and Food Safety
DOI 10.1111/1541-4337.70161PMC PMC11970350
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Abstract

Food waste causes significant environmental and economic challenges worldwide, prompting many nations to prioritize its reduction and recycling. As a nutrient‐rich material containing vitamins, proteins, and carbohydrates, it serves as a promising substrate for the cultivation of single‐cell microorganisms like yeast. Yeast cell wall polysaccharides (YCWPs), particularly chitin and β‐glucans, offer valuable applications in food, pharmaceuticals, and bioprocessing. This review highlights the biosynthesis, production, extraction, and purification of YCWP cultivated on food waste substrates. Key species including Saccharomyces cerevisiae , Pichia pastoris , and Candida spp. are discussed, with a focus on optimizing chitin and β‐glucan yield through mechanical, chemical, and enzymatic extraction methods. In addition, the structural and functional properties of β‐glucans and chitin in maintaining cell wall stability are explored, emphasizing their potential as prebiotics, dietary fibers, and biodegradable packaging materials. This review also examines the valorization of food waste in yeast cultivation, presenting a sustainable bioprocessing strategy for transforming waste into valuable bioproducts.

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  • The cell wall of M. guilliermondii is composed predominantly of β-glucans and only minor amounts of chitin.

    “the cell wall of M. guilliermondii is composed predominantly of β-glucans and only minor amounts of chitin,43”

    From Yeast to the rescue: Meyerozyma guilliermondii primes tomato vigor and resistance to Fusarium crown and root rot (2025) · cites this paper as [43]

    The Biosynthesis of YCWPs section describes β-glucans as a dominant component of yeast cell walls and chitin as relatively scarce. The Extraction Methods section reports β-glucan extraction from Candida guilliermondii, but our copy does not establish the relative β-glucan and chitin content of M. guilliermondii specifically; it also cautions that cell-wall composition varies between species. (LLM, conf=0.83)

    Experimental — accuracy not yet measured

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Metadata

Authors
Günal‐Köroğlu, D., Karabulut, G., Mohammadian, F., Can Karaca, A., Capanoglu, E., & Esatbeyoglu, T.
Affiliations
  • Istanbul Technical University (TR)
  • Department of Food Engineering, Faculty of Food Engineering Sakarya University Sakarya Türkiye
  • Leibniz University Hannover (DE)
  • Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering Istanbul Technical University Istanbul Türkiye
Corresponding author
Esatbeyoglu, Tuba
ORCID
Venue
Comprehensive Reviews in Food Science and Food Safety
Publisher
Wiley
Published
2025-04-04
Volume
24
Issue
3
Pages
e70161-e70161
ISSN
1541-4337 (ISSN-L)
DOI
10.1111/1541-4337.70161
PMC
PMC11970350
OpenAlex
W4409183017
Cited by
37
References
1
Citations by year
2026: 23 · 2025: 14
FWCI
3.26
Type
journal article
Language
en
Open access
Licence
Locations
  • Comprehensive Reviews in Food Science and Food Safety (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Istanbul Technical University Academic Open Archive (Istanbul Technical University) (submittedVersion)
  • Figshare (cc-by)
Funders
  • Gottfried Wilhelm Leibniz Universität Hannover
  • Leibniz-Gemeinschaft
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
  • Health Sciences › Medicine › Pharmacology (medical) › Fungal Biology and Applications
  • Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
Keywords
yeast cell wall polysaccharides, β-glucan, chitin, food waste valorization, Saccharomyces cerevisiae, Pichia pastoris, Candida, polysaccharide synthesis, polysaccharide extraction, polysaccharide purification, cell wall stability, prebiotics, dietary fiber, biodegradable packaging, waste recycling
MeSH terms
Food Loss and Waste, Cell Wall, Chitin, Polysaccharides, Saccharomyces cerevisiae, Yeasts, beta-Glucans

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