The DOI matches its Crossref record; 172 of the 172 references it cites were found in a registry or an index.
Molecular mechanisms of Cr(VI) resistance in bacteria and fungi
Abstract
Hexavalent chromium [Cr(VI)] contamination is one of the main problems of environmental protection because the Cr(VI) is a hazard to human health. The Cr(VI) form is highly toxic, mutagenic, and carcinogenic, and it spreads widely beyond the site of initial contamination because of its mobility. Cr(VI), crossing the cellular membrane via the sulfate uptake pathway, generates active intermediates Cr(V) and/or Cr(IV), free radicals, and Cr(III) as the final product. Cr(III) affects DNA replication, causes mutagenesis, and alters the structure and activity of enzymes, reacting with their carboxyl and thiol groups. To persist in Cr(VI)-contaminated environments, microorganisms must have efficient systems to neutralize the negative effects of this form of chromium. The systems involve detoxification or repair strategies such as Cr(VI) efflux pumps, Cr(VI) reduction to Cr(III), and activation of enzymes involved in the ROS detoxifying processes, repair of DNA lesions, sulfur metabolism, and iron homeostasis. This review provides an overview of the processes involved in bacterial and fungal Cr(VI) resistance that have been identified through 'omics' studies. A comparative analysis of the described molecular mechanisms is offered and compared with the cellular evidences obtained using classical microbiological approaches.
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Cites
Andrews, S. C., Robinson, A. K., & Rodríguez-Quiñones, F. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00055-x · Cited by 2,702 · cited 4×
“Periplasmic binding proteins shuttle ferric siderophores from the OM receptors to the ABC transporters, which in turn deliver the ferric-siderophores to the cytosol, where the complexes are dissociated (Andrews et al., 2003; Braun & Hantke, 2011; Miethke, 2013).”
BackgroundInfluentialCellular roles of DNA topoisomerases: a molecular perspective
Wang, J. C. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm831 · Cited by 2,353
Yancey, P. H. (2005) · Journal of Experimental Biology · doi:10.1242/jeb.01730 · Cited by 1,868
Interactions of chromium with microorganisms and plants
Cervantes, C., Campos‐García, J., Devars, S., Gutiérrez‐Corona, F., Loza‐Tavera, H., Guzmán, J. C. T., & Moreno‐Sánchez, R. (2001) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(01)00057-2 · Cited by 1,266
Chromium in Drinking Water: Sources, Metabolism, and Cancer Risks
Zhitkovich, A. (2011) · Chemical Research in Toxicology · doi:10.1021/tx200251t · Cited by 1,132
TonB-dependent transporters: regulation, structure, and function
Noinaj, N., Guillier, M., Barnard, & Buchanan, S. K. (2010) · Annual Review of Microbiology · doi:10.1146/annurev.micro.112408.134247 · Cited by 989
Chromium in the environment: factors affecting biological remediation
Zayed, A. M., & Terry, N. (2003) · Plant and Soil · doi:10.1023/a:1022504826342 · Cited by 959
Salnikow, K., & Zhitkovich, A. (2008) · Chemical Research in Toxicology · doi:10.1021/tx700198a · Cited by 924
Iron and Oxidative Stress in Bacteria
Touati, D. (2000) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1518 · Cited by 924
Glutathione Is a Key Player in Metal-Induced Oxidative Stress Defenses
Jozefczak, M., Remans, T., Vangronsveld, J., & Cuypers, A. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms13033145 · Cited by 810
Cited by
Coetzee, J. J., Bansal, N., & Chirwa, E. M. N. (2020) · Exposure and Health · doi:10.1007/s12403-018-0284-z · Cited by 375
Fernández, P. M., Viñarta, S. C., Bernal, A. R., Cruz, E. L., & Figueroa, L. I. C. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.05.166 · Cited by 344
Ao, M., Chen, X., Deng, T., Sun, S., Tang, Y., Morel, J. L., Qiu, R., & Wang, S. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127233 · Cited by 279
Zapana-Huarache, S. V., Romero-Sánchez, C. K., Dueñas Gonza, A. P., Torres-Huaco, F. D., & Lazarte Rivera, A. M. (2020) · International Journal of Environmental Science and Technology · doi:10.1007/s13762-020-02726-9 · Cited by 8
Metadata
- Authors
- Viti, C., Marchi, E., Decorosi, F., & Giovannetti, L.
- Venue
- FEMS Microbiology Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-07
- Volume
- 38
- Issue
- 4
- Pages
- 633-659
- ISSN
- 0168-6445 (ISSN-L)
- 1574-6976
- OpenAlex
- W2118271709
- Cited by
- 358
- References
- 172
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- Viti, C., Marchi, E., Decorosi, F., & Giovannetti, L. (2014). Molecular mechanisms of Cr(VI) resistance in bacteria and fungi. FEMS Microbiology Reviews. https://doi.org/10.1111/1574-6976.12051
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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