Adherence to insulin treatment in diabetes: can it be improved?糖尿病患者使用胰岛素治疗的依从性：它能够得到改善吗？

Doggrell, Sheila Anne; Chan, Vincent

doi:10.1111/1753-0407.12212

Cited by 29Medication Adherence and ComplianceDiabetes Management and EducationDiabetes Management and Research

Adherence to insulin treatment in diabetes: can it be improved?糖尿病患者使用胰岛素治疗的依从性：它能够得到改善吗？

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Doggrell, Sheila Anne, Chan, Vincent·2015·Journal of Diabetes

DOI 10.1111/1753-0407.12212

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Abstract

Insulin is used in all subjects with Type 1 diabetes, and when Type 2 diabetes is not controlled by oral anti‐diabetic medicines, insulin is also used in Type 2 diabetes. However, despite this use, there is still increased mortality and morbidity in subjects with diabetes, compared to subjects without diabetes. One of the factors, which may be involved in this increased mortality and morbidity in subjects with diabetes, is nonadherence to insulin. Nonadherence rates to insulin are in the range of 20–38%, and many factors contribute to the nonadherence. The major aim of the review was to determine whether interventions to improve adherence to insulin do actually improve adherence to insulin. Most studies have shown that adherence to insulin was improved by changing from the vial‐and‐syringe approach to prefilled insulin pens, but not all studies have shown that this translated into better glycemic control and clinical outcomes. The results of studies using automatic telephone messages to improve adherence to insulin to date are inconclusive. There is limited and variable evidence that an intervention by a nurse/educator, which discusses adherence to medicines, does improve adherence to insulin. In contrast, there is little or no evidence that an extra intervention by a doctor or an intervention by a pharmacist, which discusses adherence to insulin, does actually improve the measured adherence to insulin. In conclusion, rather than assuming that an intervention by a health professional discussing adherence to insulin actually improves adherence to insulin, long‐term studies investigating this are required.

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Supporting people to engage with and optimize their insulin regimens is a key challenge for HCPs, with educational interventions having limited effects.
“Supporting people to engage with and optimize their insulin regimens is a key challenge for HCPs, with educational interventions having limited effects.38”
From Increased Time in Range and Fewer Missed Bolus Injections After Introduction of a Smart Connected Insulin Pen (2020) · cites this paper as [38]

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Authors: Doggrell, S. A., & Chan, V.
Affiliations: Queensland University of Technology (AU)
Corresponding author: Doggrell, Sheila Anne
ORCID: Doggrell, Sheila Anne
Chan, Vincent
Venue: Journal of Diabetes
Publisher: Wiley
Published: 2014-11-10
Volume: 7
Issue: 3
Pages: 315-321
ISSN: 1753-0393 (ISSN-L)
1753-0407
DOI: 10.1111/1753-0407.12212
OpenAlex: W1955429230
Cited by: 29
References: 36
Citations by year: 2025: 3 · 2024: 1 · 2023: 6 · 2022: 3 · 2021: 3 · 2020: 4 · 2018: 5 · 2017: 1 · 2016: 2 · 2014: 1
FWCI: 0.17
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of Diabetes (publishedVersion)
PubMed (publishedVersion)
RMIT Research Repository (RMIT University Library) (submittedVersion)
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords: insulin adherence, medication non-adherence, type 1 diabetes, type 2 diabetes, prefilled insulin pen, telephone reminders, nurse-led intervention, pharmacist intervention, glycemic control
MeSH terms: Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Insulin, Medication Adherence

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Adherence to insulin treatment in diabetes: can it be improved?糖尿病患者使用胰岛素治疗的依从性：它能够得到改善吗？

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