Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

De Cecco, Marco, Criscione, Steven W., Peckham, Edward J., Hillenmeyer, Sara, Hamm, Eliza A., Manivannan, Jayameenakshi, Peterson, Abigail L., Kreiling, Jill A., Neretti, Nicola, Sedivy, John M.·2013·Aging Cell

DOI 10.1111/acel.12047

Cited by (458)

Items 201–300 of 458

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Madhav Jagannathan, Yukiko M Yamashita · 2017 · Cold Spring Harbor Symposia on Quantitative Biology
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Gireesh K. Bogu, Ferrán Reverter, Marc A. Martı́-Renom, Michael P. Snyder, Roderic Guigó · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
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Yuhki Yokoyama, Hengrui Zhu, Rugang Zhang, Ken-ichi Noma · 2015 · Cell Cycle
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Stephen Capone, Kwasi M. Connor, Anthony Colombo, Xin Li, Timothy J. Triche, Giridharan Ramsingh · 2018 · Experimental Hematology
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Ekaterina Proshkina, Ilya A. Solovev, Mikhail Vyacheslavovich Shaposhnikov, Alexey Moskalev · 2020 · Molecular Biology
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Kyoshiro Tsuge, Akira Shimamoto · 2022 · Genes
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Shufei Song, Javier Vasconcelos Perez, William Svitko, M. Daniel Ricketts, Elliot Dean, D. Schultz, Ronen Marmorstein, F Brad Johnson · 2019 · Aging Cell
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Evelyne Saade, Iryna Pirozhkova, Rakhan Aimbetov, Marc Lipinski, Vasily V. Ogryzko · 2015 · Aging Cell
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Annarosaria De Vito, Massimo Lazzaro, Ilaria Palmisano, Davide Cittaro, Michela Riba, Dejan Lazarevic, Makoto Bannai, Davide Gabellini, Maria Vittoria Schiaffino · 2018 · PLoS ONE
Theories and Mechanisms of Aging
Neal S. Fedarko · 2017 · Springer eBooks
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Yemima Givaty Rapp, Vanessa Ransbotyn, Gideon Grafi · 2015 · Plants
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Ekaterina Proshkina, И. А. Соловьёв, Mikhail Vyacheslavovich Shaposhnikov, A.A. Moskalev · 2020 · Molecular Biology
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Krista M. Angileri, Nornubari A. Bagia, Cédric Feschotte · 2022 · Development
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Ziqi Yue, Lulingxiao Nie, Ning Ji, Yuezhang Sun, Kangjian Zhu, Haonan Zou, Xiuxiu Song, Jiao Chen, Qi Wang · 2023 · Journal Of Clinical Periodontology
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Ahmad Luqman-Fatah, Kei Nishimori, Shota Amano, Yukiko Fumoto, Tomoichiro Miyoshi · 2024 · RNA Biology
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Luke Stephen Tain, Robert Sehlke, Ralf Leslie Meilenbrock, Thomas Leech, Jonathan Paulitz, Manopriya Chokkalingam, Nagarjuna Nagaraj, Sebastian Grönke, Jenny Fröhlich, Ilian Atanassov et al. · 2021 · eLife
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Danilo Pereira, Ursula Oggenfuss, Bruce Alan McDonald, Daniel Croll · 2021 · Microbial Genomics
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Alejandro Ocampo, Calida Mrabti, Gabriela Desdín-Micó, Gabriela Desdín-Micó, Alejandro Alonso Calleja, Alba Vílchez-Acosta, Sara Picó, Alberto Parras, Yulan Piao, Lucas Schoenfeldt et al. · 2024 · Research Square
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Clemens Hinterleitner, Hailey V. Goldberg, Domhnall McHugh, Valentin J.A. Barthet, Aveline A. Filliol, Scott W. Lowe · 2026 · Cell
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Alexander Hooftman, Alexander Keller, Andrea Ablasser · 2026 · Cell
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Mariangela Succoio, Marika Comegna, Chiara DˈAmbrosio, Andrea Scaloni, Filiberto Cimino, Raffaella Faraonio · 2015 · Journal of Proteomics
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Regina Brunauer, Brian Keith Kennedy · 2015 · Science
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Adèle Mangelinck, Clément Coudereau, Régis Courbeyrette, Khalid Ouararhni, Ali Hamiche, Christophe E. Redon, William M. Bonner, Erwin van Dijk, Céline Derbois, Robert Olaso et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
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Dimitri Belenki, Paulina Richter‐Pechańska, Zhiting Shao, Animesh Bhattacharya, Andrea Lau, José Américo Nabuco Leva Ferreira de Freitas, Gregor Kandler, Timon Hick, Xiurong Cai, Eva Scharnagl et al. · 2025 · Nature Communications
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Kailing Yang, Xiaojia Li, Keping Xie · 2023 · Cell Death and Disease
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K. S. Matveeva, Mariia Vasilieva, Ekaterina Minskaia, Рыбцов Станислав Александрович, Daniil Shevyrev · 2024 · Frontiers in Immunology
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Tianyuan Wang, Janine Hertzog Santos, Jian Feng, David C. Fargo, Li Shen, Gonzalo Riadi, Elizabeth Keeley, Zachary S. Rosh, Eric J. Nestler, Richard P. Woychik · 2016 · PLoS ONE
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Amy E. Elias, Bianca Kun, Ian M. C. Sabula, Gail Golomb‐Mello, Andrea Cespedes Zablah, Jill A. Kreiling · 2019 · Aging Cell
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Ruofan Yu, Brenna S. McCauley, Weiwei Dang · 2020 · Human Genetics
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Yoyo Chih-Yun Yu, Tony Hui, Tzu-Hao Kao, Hung‐Fu Liao, Chih-Yi Yang, Chia‐Chun Hou, Hsin-Ting Hsieh, Jen‐Yun Chang, Yi‐Tzang Tsai, Marina Pinskaya et al. · 2020 · Frontiers in Cell and Developmental Biology
Clinical Implications of Cellular Senescence on Wound Healing
S.G. Resnik, Andjela N. Egger, Beatriz Abdo Abujamra, Ivan Jozic · 2020 · Current Dermatology Reports
Transcriptome-wide piRNA profiling in human brains for aging genetic factors.
Qiao Mao, Longhua Fan, Xiaoping Wang, Xiandong Lin, Yuping Cao, Chengchou Zheng, Yong Zhang, Huihao Zhang, Rolando García-Milian, Longli Kang et al. · 2019 · PubMed
Systemic Factors Mediate Reversible Age-Associated Brain Dysfunction
Andrew R. Mendelsohn, James W. Larrick · 2014 · Rejuvenation Research
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M. Smith, Devin Wahl, Alyssa N. Cavalier, Gabriella T. McWilliams, Matthew J. Rossman, G Giordano, Angela D. Bryan, Douglas R. Seals, Thomas J. LaRocca · 2024 · GeroScience
Hydra as a tractable, long-lived model system for senescence
Anthony J. Bellantuono, Diane M. Bridge, Daniel E. Martínez · 2014 · Invertebrate Reproduction & Development
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Keegan, Richard M., Talbot, Lillian R., Chang, Yung-Heng, Metzger, Michael J., Dubnau, Josh · 2021 · PLOS Genetics
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Xingguang Luο, Xiaoyun Guo, Yunlong Tan, Yong Zhang, Rolando García-Milian, Zhiren Wang, Jing Shi, Ting Yue Yu, Jiawu Ji, Xiaoping Wang et al. · 2020 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
Chromatin conformational changes at human satellite II contribute to the senescence phenotype in the tumor microenvironment
Miyata, Kenichi, Zhou, Xiangyu, Nishio, Mika, Hanyu, Aki, Chiba, Masatomo, Kawasaki, Hiroko, Osako, Tomo, Takeuchi, Kengo, Ohno, Shinji, Ueno, Takayuki et al. · 2023 · Proceedings of the National Academy of Sciences
Xrp1 governs the stress response program to spliceosome dysfunction
Dimitrije Stanković, Luke Stephen Tain, Mirka Uhlířová · 2024 · Nucleic Acids Research
Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease
Alexandra M. D’Ordine, G. Jogl, John M. Sedivy · 2024 · Nature Communications
Somatizing the transposons action
Élgion L. S. Loreto, Camila Moura Pereira · 2017 · Mobile Genetic Elements
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Mohammad Banazadeh, Ardavan Abiri, Mohammad Mahdi Poortaheri, Lida Asnaashari, Mohammad Amin Langarizadeh, Hamid Forootanfar · 2024 · International Journal of Biological Macromolecules
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Stéphane Lopes‐Paciencia, Gerardo Ferbeyre · 2025 · FEBS Journal
Accelerated Senescence of Cancer Stem Cells: A Failure to Thrive or a Route to Survival?
Jekaterina A. Erenpreisa, Kristīne Salmiņa, Mark Steven Cragg · 2017 · InTech eBooks
Transposable Elements in Pluripotent Stem Cells and Human Disease
Gang Ma, Isaac A. Babarinde, Xuemeng Zhou, Andrew P. Hutchins · 2022 · Frontiers in Genetics
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Camila Corradi, Juliana Brandstetter Vilar, Vanessa Candiotti Buzatto, Tiago Antônio de Souza, Ligia Pereira Castro, Veridiana Munford, Rodrigo De Vecchi, Pedro A. F. Galante, Fernanda Orpinelli Ramos do Rego, Thiago L. A. Miller et al. · 2023 · Carcinogenesis
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Qiao Mao, Xiaoping Wang, Bin Chen, Longhua Fan, Shuhong Wang, Yong Zhang, Xiandong Lin, Yuping Cao, Yun‐Cheng Wu, Jiawu Ji et al. · 2020 · Frontiers in Neuroscience
The Y chromosome contributes to sex-specific aging in Drosophila
Emily J. Brown, Alison H. Nguyen, Doris Bachtrog · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Expression of most retrotransposons in human blood correlates with biological aging
Yi-Ting Tsai, Nogayhan Seymen, Ian Richard Thompson, Xinchen Zou, Warisha Mumtaz, Sıla Gerlevik, Ghulam Jeelani Mufti, Mohammad Mahdi Karimi · 2024 · eLife
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Christine R. Keenan, Hannah D. Coughlan, Nadia Iannarella, Andrés Tapia del Fierro, Andrew Keniry, Timothy M. Johanson, Wing Fuk Chan, Alexandra L. Garnham, Lachlan W. Whitehead, Marnie E. Blewitt et al. · 2024 · Genome Research
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Anna Le Breton, Margarida P. Bettencourt, Anne-Valérie Gendrel · 2024 · Frontiers in Cell and Developmental Biology
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Stéphane Lopes‐Paciencia, Véronique Bourdeau, Marie‐Camille Rowell, Davoud Amirimehr, Jordan Guillon, Paloma Kalegari, Arnab Barua, Vincent Quoc‐Huy Trinh, Féryel Azzi, Simon Turcotte et al. · 2024 · Cell Reports
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Miriam Merenciano, Anaïs E. A. Larue, Chloé Garambois, William Vilas Boas Nunes, Cristina P Vieira · 2025 · Genome Biology and Evolution
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Timothy Nacarelli, Ashley Azar, Manali Potnis, Gregg Johannes, Joshua Chang Mell, F. Brad Johnson, Holly M. Brown‐Borg, Eishi Noguchi, Christian Sell · 2022 · Molecular Biology of the Cell
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Ming‐Xia Ge, Qin Yu, Gong‐Hua Li, Liqin Yang, Yonghan He, Ji Li, Qing‐Peng Kong · 2022 · Computational and Structural Biotechnology Journal
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Ana Mota, Szymon Berezicki, Erik Wernersson, Luuk Harbers, Xiaoze Li-Wang, Katarina Gradin, Christiane Peuckert, Nicola Crosetto, Magda Bienko · 2022 · Nature Communications
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Peter Lenárt, Julie Bienertová Vašků · 2016 · Mechanisms of Ageing and Development
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Amr R. Ghanam, Jun Cao, Xuan Ouyang, Xiaoyuan Song · 2019 · Oxidative Medicine and Cellular Longevity
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Samanta Raboni, Serena Montalbano, Stephanie Stransky, Benjamin A. Garcia, Annamaria Buschini, Stefano Bettati, Simone Sidoli, Andrea Mozzarelli · 2021 · Frontiers in Molecular Biosciences
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Tianpeng Zhang, Allancer Nunes, Jieun Lee, Dana Larocca, Giovanni Camussi, Sai Kiang Lim, Vicky U. Bascones, Luise A. Angelini, Ryan D. O'Kelly, Xiao Dong et al. · 2025 · Aging Cell
Elimination of virus-like particles reduces protein aggregation and extends replicative lifespan in Saccharomyces cerevisiae
Kara L. Schneider, X. Hao, Katharina Keuenhof, Lisa Larsson Berglund, Arthur Fischbach, Doryaneh Ahmadpour, Srishti Chawla, Patricia Gómez-Gejo, Johanna Louise Höög, Per O. Widlund et al. · 2024 · Proceedings of the National Academy of Sciences
Long-term voluntary wheel running effects on markers of long interspersed nuclear element-1 in skeletal muscle, liver, and brain tissue of female rats
Shelby C. Osburn, Paulo H. C. Mesquita, Frances K. Neal, Melissa N. Rumbley, Matthew T. Holmes, Bradley A. Ruple, Christopher Brooks Mobley, Michael D. Brown, Danielle J. McCullough, Andreas N. Kavazis et al. · 2022 · American Journal of Physiology-Cell Physiology
Senescence and the Genome
Joanna M. Bridger, Helen A. Foster · 2020 · Springer eBooks
Transposable Element Landscape in Drosophila Populations Selected for Longevity
Daniel K. Fabian, Handan Melike Dönertaş, Matías Fuentealba, Linda Partridge, Janet M. Thornton · 2021 · Genome Biology and Evolution
Glial reactivity and cognitive decline follow chronic heterochromatin loss in neurons
Andrew G. Newman, Jafar Sharif, Paraskevi Bessa, Sami Zaqout, Josie Brown, D. Richter, R. Dannenberg, Manabu Nakayama, Susanne G. Mueller, T. Schaub et al. · 2025 · Nature Communications
Transposable Elements: Emerging Therapeutic Targets in Neurodegenerative Diseases
Shrishti Singh, Maheshkumar R. Borkar, Lokesh Kumar Bhatt · 2024 · Neurotoxicity Research
Overview of Autophagy
M.A. Hayat · 2017 · Elsevier eBooks
Survival at the Brink
Jekaterina A. Erenpreisa, Kristīne Salmiņa, Alexander Belyayev, Inna Inashkina, Mark Steven Cragg · 2017 · Elsevier eBooks
Deficiency of TRDMT1 impairs exogenous RNA-based response and promotes retrotransposon activity during long-term culture of osteosarcoma cells
Gabriela Betlej, Anna Lewińska, Jagoda Adamczyk‐Grochala, Dominika Błoniarz, Iwona Rzeszutek, Maciej Wnuk · 2022 · Toxicology in Vitro
Differential MC5R loss in whales and manatees reveals convergent evolution to the marine environment
Jian Liu, Mingrong Shu, Shaobo Liu, Jingwen Xue, Haidi Chen, Wen Li, Jingfan Zhou, Amanullah Amanullah, Miao Guan, Ji Bao et al. · 2022 · Development Genes and Evolution
Protein Carbonylation in Aging and Senescence
Jeannette König, Tobias Jung, Tilman Grune · 2017 · Wiley eBooks
Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies
Xinran O. Zhao, Jiabin Zong, Yuxiao Liu, Tuersun Aili, Min Qiu, Jiehong Wu, Bo Hu · 2024 · Aging and Disease
Activation of transposable elements and genetic instability during long-term culture of the human fungal pathogen Candida albicans
Leszek Potocki, Ewelina Kuna, Kamila Filip, Beata Kasprzyk, Anna Lewińska, Maciej Wnuk · 2019 · Biogerontology
Signature changes in the expressions of protein-coding genes, lncRNAs, and repeat elements in early and late cellular senescence
Gökhan Karakülah, Cihangir Yandım · 2020 · TURKISH JOURNAL OF BIOLOGY
Impact of superovulation and in vitro fertilization on LINE-1 copy number and telomere length in C57BL/6 J mice blastocysts
Thalita Souza Berteli, Fang Wang, Fabiana B. Kohlrausch, Caroline Mantovani da Luz, Fernanda Veronese de Oliveira, David Lawrence Keefe, Paula Andrea Navarro · 2022 · Molecular Biology Reports
Mobile DNA Elements: The Seeds of Organic Complexity on Earth
Laleh Habibi, Mehrdad Pedram, Akbar Amirfiroozi, Khadijeh Bonyadi · 2015 · DNA and Cell Biology
Growth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocations
Patrick H. Maxwell · 2016 · BMC Genetics
Contribution of Retrotransposable Elements to Aging
Jill A. Kreiling, Brian C. Jones, Jason G. Wood, Marco De Cecco, Steven W. Criscione, Nicola Neretti, Stephen L. Helfand, John M. Sedivy · 2017 · Springer eBooks
Genomic instability and aging: Causes and consequences
Marta Gerasymchuk · 2021 · Elsevier eBooks
Molecular and biological effects of Cisplatin in Drosophila
Daniela Moreira Mombach, Tiago Minuzzi Freire da Fontoura Gomes, Mônica Medeiros Silva, Élgion L. S. Loreto · 2021 · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology