Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

Cited by (458)

Items 401–458 of 458

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  4. Roles of piRNA Pathway Components Piwi and Aubergine In Drosophila melanogaster Female Germline Development
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  5. Molecular Mechanisms of Cardiovascular Aging
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  6. Contrasting effects of aging on the expression of transposons, the piRNA machinery and mitochondrial transcripts in the Drosophila ovary
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  7. Spontaneous retrotranspositions in normal tissues are rare and associated with cell-type-specific differentiation
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  8. The Origins of Ageing
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  10. Line-1 Retrotransposition and the Impact on Aging Rodent Skeletal Muscle Tissue
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  11. Prospects in the Search for Peptides for Specific Regulation of Aging
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  12. LINE-1 RNA Expression is Higher in Older Human Skeletal Muscle but Decreases With Endurance Exercise and Physical Activity
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  13. HSATII RNA is induced via a non-canonical ATM-regulated DNA-damage response pathway and facilitates tumor cell proliferation and movement
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  14. Aging-associated changes in metabolic regulation of epigenetic modifications and gene expression
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  15. Investigating the Role of Chromatin Remodeler FOXA1 in Ferroptotic Cell Death
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  16. A centromeric RNA-associated protein complex affects germ line development in Drosophila melanogaster
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  17. Age-dependent transcriptional and epigenetic alterations in mouse hepatocytes
    Sharma, Ankur · 2021 · DR-NTU (Nanyang Technological University)
  18. Faculty Opinions recommendation of L1 drives IFN in senescent cells and promotes age-associated inflammation.
    Michael Zhang, Zhenyu Xuan · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  19. Faculty Opinions recommendation of L1 drives IFN in senescent cells and promotes age-associated inflammation.
    Jean Pieters, Ravindra Mode · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  20. Epigenetics of aging
    Christina Pagiatakis, Rosalba Gornati, Roberto Papait · 2023 · Elsevier eBooks
  21. Epigenetic Iinsights into the Senescence of Porcine Fetal Fibroblasts induced by Passaging
    Jiaying Bi, Dayu Wang, Fuquan Zhu, Xinyue Lu, Yan Xie, Huijun Liu, Meixia Wang, Xu He, Yuan Zhu Jiang, Peng Liu et al. · 2023 · Cell Cycle
  22. Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
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  23. Transposable Element (TE) insertion predictions from RNAseq inputs and TE impact on RNA splicing and gene expression in Drosophila brain transcriptomes
    Md Fakhrul Azad, Tong Tong, Nelson C. Lau · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  24. The number of Y chromosomes is positively associated with transposable element expression in humans, in line with the toxic Y hypothesis
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  25. Neurological Impact of Type I Interferon Dysregulation
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  26. Author response: Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
    Yi-Ting Tsai, Nogayhan Seymen, Ian Richard Thompson, Xinchen Zou, Warisha Mumtaz, Sıla Gerlevik, Ghulam Jeelani Mufti, Mohammad Mahdi Karimi · 2024 · eLife
  27. eLife Assessment: Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
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  28. Reviewer #1 (Public Review): Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
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  29. Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
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  30. Transposable element small and long RNAs in aging brains and implications in Huntington’s and Parkinson’s disease
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  31. De-repression of Transposable Elements by Histone Hyperacetylation Leads to Sterile Inflammation in Preeclampsia
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  32. Fragmentation of nucleoli in senescent cancer cells is associated with increased levels of polyadenylated transcripts derived from noncoding regions of rDNA units
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  33. Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain
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  34. Ageing versus developmental silencing: Answers from the epigenome
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  35. Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain
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  36. Transposable Elements and Their Roles in Genome Architecture
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  37. Transposable Elements as Drivers of Age-Related Neurodegenerative Disease
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  38. Transposable elements in aging: From biomarkers to effectors
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  39. Exploring the association between DNA methylation and pancreatic cancer susceptibility through epigenome-wide Mendelian randomization and multi-omics data integration
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  40. Transposable elements as dynamic regulators of skeletal muscle development, regeneration and aging
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  41. Metformin-induced longevity is associated with retrotransposon dynamics in yeast chronological aging
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  42. Étude des altérations du programme de réplication lors du vieillissement cellulaire : peuvent-elles être reprogrammées ?
    Hélène Schwerer · 2014 · theses.fr (ABES)
  43. Role of thrombopoietin in DNA repair an genomic integrity in hematopoietic stem cells
    Daniela Barbieri · 2017 · theses.fr (ABES)
  44. Generation of antisense RNAs at convergent gene loci in cells undergoing senescence
    Maharshi Krishna Deb · 2016 · theses.fr (ABES)
  45. Analyse fonctionnelle du variant d’histone H2A.J impliqué dans le développement d’un phénotype pro-inflammatoire en sénescence induite par des dommages à l’ADN
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  46. Implication du gène Dicer1 dans le vieillissement et ses pathologies chez la souris
    Aurore de Cauwer · 2020 · theses.fr (ABES)
  47. L1 retrotransposon activity in muscle cells
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  48. Découverte d'une sénescence associée à un phénotype sécrétoire déclenchée par les défauts mécaniques de la cellule endothéliale lors de la perte de CCM2 dans un modèle de cavernome cérébral
    Daphné Vannier · 2020 · theses.fr (ABES)
  49. Rôles de très longs ARNs non codants intergéniques dans la réorganisation 3D du génome au cours de la sénescence
    Julien Ouvrard · 2023 · theses.fr (ABES)
  50. Étude de l'évolution des interactions moléculaires chez les Eucaryotes par des méthodes de comparaison de réseaux dans le but d'identifier des processus ancestraux partagés associés au vieillissement
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  51. Characterization of Cellular Senescence in Primary Human Astrocytes
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  52. Locus-specific LINE-1 mRNA expression reflects cell-type- and stimulus-specific senescence states
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  54. Epigenetic drift and LINE-1 activation in aging brain: Implications for neurodegenerative disease
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  55. SIRT1 Silences L1 Retrotransposons by Stabilizing Heterochromatin‐Modifying Complexes
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  56. Aging and Reproductive Cancers: An Integrative View on Cell-Free DNA and Transposable Elements
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  57. The therapeutic potential of transposable element activity modulation
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  58. Chromatin signaling in aging and cellular senescence
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