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Cited by 16Substance Abuse Treatment and OutcomesMobile Health and mHealth ApplicationsDigital Mental Health Interventions

Effect of a 1‐year short message service in detoxified alcohol‐dependent patients: a multi‐center, open‐label randomized controlled trial

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Lucht, Michael, Quellmalz, Anne, Mende, Meinhard, Broda, Anja, Schmiedeknecht, Anett, Brosteanu, Oana, Höppner‐Buchmann, Jacqueline, Langosch, Jens +7 more·2021·Addiction
DOI 10.1111/add.15313
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Abstract

BACKGROUND AND AIMS: Existing evidence suggests that text message interventions can help people to reduce their alcohol consumption. However, studies with alcohol-dependent patients are lacking. In this study a 1-year automatic mobile phone-based short messaging service (SMS) intervention on alcohol consumption in patients after alcohol detoxification in hospital was compared with treatment as usual. DESIGN: Multi-center, randomized, controlled, two parallel-group, observer-blinded trial. SETTING AND PARTICIPANTS: area in Germany). A total of 462 patients with alcohol dependence (ICD-10) were included during inpatient detoxification treatment. Patients were randomly assigned (1 : 1) to an SMS intervention and treatment as usual (SMS + TAU; n = 230; mean age: 45.4 years; 22.6% women) or TAU alone (n = 232 mean age: 44.5 years; 22.8% women). Planned, automated messages were sent to patients over 1 year to record assistance needs. A 'yes' or missing response triggered a telephone call from a hospital therapist. Outcome was assessed by an independent survey center. MEASUREMENTS: The primary end-point was a three-category alcohol consumption measure covering months 10-12 after discharge: abstinence, non-heavy drinking, heavy drinking [men > 60 g/day; women > 40 g/day equal to World Health Organization (WHO) criteria: high risk and very high risk, mean consumption]. Secondary end-points were number of abstinent days over 12 months and frequency of abstinence. RESULTS: The arms differed primarily in the heavy drinking category (intervention group 22.2%, TAU-only group 32.3%) in months 9-12. This is reflected by an odds ratio (OR) = 1.68, 95% confidence interval (CI) = 1.11-2.54, P = 0.015 for heavy drinking versus non-heavy drinking/abstinence. No difference between treatments was found with respect to any drinking versus abstinence (OR = 1.13). These results were confirmed by models adjusting for randomization strata. CONCLUSIONS: In Germany, a 12-month mobile phone short messaging service-based intervention enhanced the reduction in heavy drinking for 1 year in routine care among adults with alcohol dependence discharged from inpatient alcohol detoxification.

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Authors
Lucht, M., Quellmalz, A., Mende, M., Broda, A., Schmiedeknecht, A., Brosteanu, O., Höppner‐Buchmann, J., Langosch, J., Stuppe, M., Schomerus, G., Klauer, T., Grabe, H. J., Freyberger, H. J., John, U., & Meyer, C.
Affiliations
  • Universitätsmedizin Greifswald (DE)
  • Helios Kliniken (DE)
  • Leipzig University (DE)
  • Helios Hospital Schwerin (DE)
  • Bethanien Hospital for Psychiatry, Psychosomatics, and Psychotherapy Greifswald Germany
Corresponding author
Lucht, Michael
ORCID
Venue
Addiction
Publisher
Wiley
Published
2020-12-27
Volume
116
Issue
6
Pages
1431-1442
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
DOI
10.1111/add.15313
OpenAlex
W3097344511
Cited by
16
References
33
Citations by year
2025: 3 · 2024: 7 · 2023: 2 · 2022: 3 · 2021: 1
FWCI
1.07
Type
journal article
Language
en
Open access
Licence
Locations
  • Addiction (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft (DFG Lu 849/2‐1)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Keywords
alcoholism, short message service, mobile phone intervention, alcohol detoxification, heavy drinking, abstinence, post-discharge follow-up, automated messaging, telephone follow-up, inpatient detoxification
MeSH terms
Adult, Alcohol Drinking, Alcoholism, Female, Humans, Male, Middle Aged, Research Design, Cell Phone, Text Messaging

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