Options for screening for gestational diabetes mellitus during the SARS‐CoV‐2 pandemic
Open accessAbstract
The balance between avoiding severe acute respiratory syndrome coronavirus‐2 contagion and reducing wider clinical risk is unclear for gestational diabetes mellitus (GDM) testing. Recent recommendations promote diagnostic approaches that limit collection but increase undiagnosed GDM, which potentially increases adverse pregnancy outcome risks. The most sensitive approach to detecting GDM at 24–28 weeks beyond the two‐hour oral glucose tolerance test (OGTT) is a one‐hour OGTT (88% sensitivity). Less sensitive approaches use fasting glucose alone (≥5.1 mmol/L: misses 44–54% GDM) or asking ~20% of women for a second visit (fasting glucose 4.7–5.0 mmol/L (62–72% sensitive)). Choices should emphasise local and patient decision‐making.
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Simplifying the diagnosis of GDM in order to avoid the risk of COVID-19 infection was associated with the risk of not diagnosing GDM by as much as 20-30%.
“However, simplifying the diagnosis of GDM in order to avoid the risk of COVID-19 infection was unfortunately associated with the risk of not diagnosing GDM by as much as 20–30%, which may affect obstetric outcomes [63,64,65].”
From Gestational Diabetes Mellitus—Recent Literature Review (2022) · cites this paper as [64]
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- Authors
- Simmons, D., Rudland, V. L., Wong, V., Flack, J., Mackie, A., Ross, G. P., Coat, S., Dalal, R., Hague, B. M., & Cheung, N. W.
- Affiliations
- Camden and Campbelltown Hospitals (AU)
- Westmead Hospital (AU)
- Liverpool Hospital (AU)
- Bankstown Hospital Sydney New South Wales Australia
- Royal Prince Alfred Hospital (AU)
- Women's and Children's Hospital (AU)
- University of Adelaide and Women’s and Children’s Hospital Adelaide South Australia Australia
- Corresponding author
- Simmons, David
- ORCID
- Venue
- Australian and New Zealand Journal of Obstetrics and Gynaecology
- Publisher
- Wiley
- Published
- 2020-08-10
- Volume
- 60
- Issue
- 5
- Pages
- 660-666
- ISSN
- 0004-8666 (ISSN-L)
- 1479-828X
- PMC
- PMC7436309
- OpenAlex
- W3047649906
- Cited by
- 16
- References
- 23
- Citations by year
- 2026: 2 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 2 · 2020: 3
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Australian and New Zealand Journal of Obstetrics and Gynaecology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › COVID-19 Impact on Reproduction
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- gestational diabetes mellitus, screening, SARS-CoV-2, COVID-19 pandemic, fasting blood glucose, diagnostic sensitivity, missed diagnosis, adverse pregnancy outcomes, patient decision-making, clinical risk
- MeSH terms
- Clinical Decision-Making, COVID-19, Adult, Blood Glucose, Female, Gestational Age, Glucose Tolerance Test, Humans, Patient Isolation, Pneumonia, Viral, Pregnancy, Pregnancy Complications, Infectious, Pregnancy Outcome, Prenatal Diagnosis, Diabetes, Gestational, Infection Control, Coronavirus Infections, Risk Assessment, Pandemics
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