The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Infection in Organ Transplantation
Open accessAbstract
The prevention, diagnosis, and management of infectious disease in transplantation are major contributors to improved outcomes in organ transplantation. The risk of serious infections in organ recipients is determined by interactions between the patient's epidemiological exposures and net state of immune suppression. In organ recipients, there is a significant incidence of drug toxicity and a propensity for drug interactions with immunosuppressive agents used to maintain graft function. Thus, every effort must be made to establish specific microbiologic diagnoses to optimize therapy. A timeline can be created to develop a differential diagnosis of infection in transplantation based on common patterns of infectious exposures, immunosuppressive management, and antimicrobial prophylaxis. Application of quantitative molecular microbial assays and advanced antimicrobial therapies have advanced care. Pathogen-specific immunity, genetic polymorphisms in immune responses, and dynamic interactions between the microbiome and the risk of infection are beginning to be explored. The role of infection in the stimulation of alloimmune responses awaits further definition. Major hurdles include the shifting worldwide epidemiology of infections, increasing antimicrobial resistance, suboptimal assays for the microbiologic screening of organ donors, and virus-associated malignancies. Transplant infectious disease remains a key to the clinical and scientific investigation of organ transplantation.
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The 2016 revision of the World Health Organization classification of lymphoid neoplasms
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Heterologous immunity provides a potent barrier to transplantation tolerance
Adams, A. B., Williams, M. A., Jones, T. R., Shirasugi, N., Durham, M. M., Kaech, S. M., Wherry, E. J., Onami, T., Lanier, J. G., Kokko, K. E., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200317477 · Cited by 616
T cell responses to cytomegalovirus
Klenerman, P., & Oxenius, A. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.38 · Cited by 483
Byrnes, E. J., Li, W., Lewit, Y., Ma, H., Voelz, K., Ren, P., Carter, D. A., Chaturvedi, V., Bildfell, R. J., May, R. C., et al. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000850 · Cited by 330
Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis
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Safety and tolerability of caspofungin acetate in the treatment of fungal infections
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Cited by
van Delden, C., Stampf, S., Hirsch, H. H., Manuel, O., Meylan, P., Cusini, A., Hirzel, C., Khanna, N., Weisser, M., Garzoni, C., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciz1113 · Cited by 319
Lucey, M. R., Furuya, K. N., & Foley, D. P. (2023) · New England Journal of Medicine · doi:10.1056/nejmra2200923 · Cited by 182
Neofytos, D., Chatzis, O., Nasioudis, D., Boely Janke, E., Doco Lecompte, T., Garzoni, C., Berger, C., Cussini, A., Boggian, K., Khanna, N., et al. (2018) · Transplant Infectious Disease · doi:10.1111/tid.12898 · Cited by 108
Jiang, J., Chen, S., Tsou, T., McGinnis, C. S., Khazaei, T., Zhu, Q., Park, J. H., Strazhnik, I.-M., Vielmetter, J., Gong, Y., et al. (2023) · doi:10.1101/2023.04.19.537364 · Cited by 21
Metadata
- Authors
- Fishman, J. A.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2017-04
- Volume
- 17
- Issue
- 4
- Pages
- 856-879
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W2580949479
- Cited by
- 809
- References
- 8
- FWCI
- 62.66
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
