Omalizumab rapidly improves angioedema‐related quality of life in adult patients with chronic spontaneous urticaria: X‐ACT study data
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Background: The X‐ACT study aimed to examine the effect of omalizumab treatment on quality of life (QoL) in chronic spontaneous urticaria (CSU) patients with angioedema refractory to high doses of H 1‐antihistamines. Methods: In X‐ACT, a phase III, double‐blind, placebo‐controlled study, CSU patients (18‐75 years) with ≥4 angioedema episodes during the 6 months before inclusion were randomized (1:1) to receive omalizumab 300 mg or placebo every 4 weeks for 28 weeks. Angioedema‐related QoL, skin‐related QoL impairment, and psychological well‐being were assessed. Results: Ninety‐one patients were randomized and 68 (omalizumab, n = 35; placebo, n = 33) completed the 28‐week treatment period. At baseline, the mean (SD) total Angioedema QoL (AE‐QoL; 56.2 [18.7] and 59.9 [19.2]) and Dermatology Life Quality Index (DLQI; 14.6 [5.7] and 16.6 [7.3]) score were high in the omalizumab and placebo group, respectively. At Week 4 (after the first treatment), the least squares mean difference in the AE‐QoL and DLQI score between groups was −17.6 (P < .001) and −7.2 (P < .001), respectively. Significant QoL improvements in the omalizumab vs placebo groups continued until Week 28, but returned to placebo levels at the follow‐up visit. The mean (SD) baseline 5‐item World Health Organization Well‐being Index was 10.0 (5.5, omalizumab) and 7.7 (5.3, placebo), which increased above the depression threshold (<13) from Week 4 and throughout with omalizumab but not placebo treatment. Compared to placebo, omalizumab was also associated with decreased fear of suffocation due to angioedema. Conclusions: Our findings support omalizumab treatment in patients with severe H1‐antihistamine‐refractory CSU with angioedema.
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Angioedema can cause rapid and unpredictable swelling that may cause a feeling of suffocation.
“There may be rapid and unpredictable swelling. This can cause a feeling of suffocation [8–10].”
From Acceptance and perceived usefulness of digital health services in the management of chronic urticaria: a survey of patients and physicians (2025) · cites this paper as [9]
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Dermatology Life Quality Index (DLQI)-a simple practical measure for routine clinical use
Finlay, A. Y., & KHAN, G. K. (1994) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.1994.tb01167.x · Cited by 5,610 · see citing works
Zuberbier, T., Aberer, W., Asero, R., Bindslev‐Jensen, C., Brzoza, Z., Canonica, G. W., Church, M. K., Ensina, L. F., Giménez‐Arnau, A. M., Godse, K. V., et al. (2014) · Allergy · doi:10.1111/all.12313 · Cited by 1,206 · see citing works
Self-citationKaplan, A. P., Ledford, D. K., Ashby, M. A., Canvin, J., Zazzali, J. L., Conner, E. R., Veith, J. H., Kamath, N., Staubach, P., Jakob, T., et al. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.05.013 · Cited by 570 · see citing works
Self-citationSaini, S. S., Bindslev‐Jensen, C., Maurer, M., Grob, J., Başkan, E. B., Bradley, M. S., Canvin, J., Rahmaoui, A., Georgiou, P., Alpan, O., et al. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.306 · Cited by 469 · see citing works
Self-citationZuberbier, T., Aberer, W., Asero, R., Bindslev‐Jensen, C., Brzoza, Z., Canonica, G. W., Church, M. K., Ensina, L. F., Giménez‐Arnau, A. M., Godse, K. V., et al. (2015) · Dermatology Review · doi:10.5114/dr.2015.51433 · Cited by 428 · see citing works
Self-citationSaini, S. S., Rosén, K. E., Hsieh, H.-J., Wong, D. A., Conner, E. R., Kaplan, A. P., Spector, S. L., & Maurer, M. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.06.010 · Cited by 393 · see citing works
Self-citationMaurer, M., Altrichter, S., Bieber, T. R. M., Biedermann, T., Bräutigam, M., Seyfried, S., Brehler, R., Grabbe, J., Hunzelmann, N., Jakob, T., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.04.038 · Cited by 363 · see citing works
Self-citationDevelopment and construct validation of the angioedema quality of life questionnaire
Weller, K., Groffik, A., Magerl, M. A. K., Tohme, N., Martus, P., Krause, K., Metz, M., Staubach, P., & Maurer, M. (2012) · Allergy · doi:10.1111/all.12007 · Cited by 304 · see citing works
Self-citationZhao, Z., Ji, C., Yu, W., Meng, L., Hawro, T., Wei, J., & Maurer, M. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.12.1342 · Cited by 300 · see citing works
Self-citationMetz, M., Ohanyan, T., Church, M. K., & Maurer, M. (2013) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2013.08.011 · Cited by 274 · see citing works
Self-citationKrieger, T., Zimmermann, J., Huffziger, S., Ubl, B., Diener, C., Kuehner, C., & Holtforth, M. G. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.12.015 · Cited by 263 · see citing works
Development, validation, and initial results of the Angioedema Activity Score
Weller, K., Groffik, A., Magerl, M. A. K., Tohme, N., Martus, P., Krause, K., Metz, M., Staubach, P., & Maurer, M. (2013) · Allergy · doi:10.1111/all.12209 · Cited by 208 · see citing works
Self-citationWeller, K., Magerl, M. A. K., Peveling‐Oberhag, A., Martus, P., Staubach, P., & Maurer, M. (2016) · Allergy · doi:10.1111/all.12900 · Cited by 167 · see citing works
Self-citationStaubach, P., Dechene, M., Metz, M., Magerl, M. A. K., Siebenhaar, F., Weller, K., Zezula, P., Eckhardt‐Henn, A., & Maurer, M. (2011) · Acta Dermato Venereologica · doi:10.2340/00015555-1109 · Cited by 147 · see citing works
Self-citationMetz, M., Staubach, P., Bauer, A., Brehler, R., Gericke, J., Kangas, M., Ashton‐Chess, J., Jarvis, P., Georgiou, P., Canvin, J., et al. (2017) · Theranostics · doi:10.7150/thno.18304 · Cited by 137 · see citing works
Self-citationMaurer, M., Staubach, P., Raap, U., Richter‐Huhn, G., Bauer, A., Ruëff, F., Jakob, T., Yazdi, A. S., Mahler, V., Wagner, N., et al. (2017) · Clinical & Experimental Allergy · doi:10.1111/cea.12900 · Cited by 131 · see citing works
Self-citationStaubach, P., Metz, M., Chapman‐Rothe, N., Sieder, C., Bräutigam, M., Canvin, J., & Maurer, M. (2016) · Allergy · doi:10.1111/all.12870 · Cited by 130 · see citing works
Self-citationShikiar, R., Harding, G., Leahy, M., & Lennox, R. D. (2005) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-3-36 · Cited by 107 · see citing works
Brooks, A. J., Rowse, G., Ryder, A., Peach, E. J., Corfe, B. M., & Lobo, A. J. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13645 · Cited by 98 · see citing works
Emerging concepts in the diagnosis and treatment of patients with undifferentiated angioedema
Bernstein, J. A., & Moellman, J. J. (2012) · International Journal of Emergency Medicine · doi:10.1186/1865-1380-5-39 · Cited by 91 · see citing works
Chronic idiopathic urticaria and anxiety symptoms
Barbosa, F., Freitas, J., & Barbosa, A. (2011) · Journal of Health Psychology · doi:10.1177/1359105311398682 · Cited by 70 · see citing works
Maurer, M., Sofen, H. L., Ortiz, B. D., Kianifard, F., Gabriel, S., & Bernstein, J. A. (2016) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.14075 · Cited by 61 · see citing works
Self-citationHergüner, S., Kılıç, G., Karakoç, S., Tamay, Z., Tüzün, Ü., & Güler, N. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.10138.x · Cited by 59 · see citing works
Finlay, A. Y., Kaplan, A. P., Beck, L. A., Antonova, E. N., Balp, M. M., Zazzali, J. L., Khalil, S. I., & Maurer, M. (2017) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.14384 · Cited by 54 · see citing works
Self-citationChoi, W.-S., Lim, E., Ban, G., Kim, J., Shin, Y. S., Park, H., & Ye, Y. (2016) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2015.195 · Cited by 50 · see citing works
Omalizumab: A Review of Its Use in Patients with Chronic Spontaneous Urticaria
McCormack, P. L. (2014) · Drugs · doi:10.1007/s40265-014-0290-9 · Cited by 38 · see citing works
The urticarias: pathophysiology and management
Grattan, C. E. H. (2012) · Clinical Medicine · doi:10.7861/clinmedicine.12-2-164 · Cited by 34 · see citing works
Current and future therapies for the treatment of histamine-induced angioedema
James, C. A., & Bernstein, J. A. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1282461 · Cited by 32 · see citing works
Angioedema in the omalizumab chronic idiopathic/spontaneous urticaria pivotal studies
Zazzali, J. L., Kaplan, A. P., Maurer, M., Raimundo, K., Trzaskoma, B. L., Solari, P. G., Antonova, E. N., Mendelson, M. H., & Rosén, K. E. (2016) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2016.06.024 · Cited by 30 · see citing works
Self-citationAn evidence based therapeutic approach to hereditary and acquired angioedema
Bork, K. (2014) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000082 · Cited by 23 · see citing works
Hallak, B., Konu, P., Lang, F., Simon, C., & Monnier, P. (2012) · Case Reports in Otolaryngology · doi:10.1155/2012/405824 · Cited by 5 · see citing works
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Fokkens, W. J., Lund, V. J., Bachert, C., Mullol, J., Bjermer, L. H., Bousquet, J. J., Canonica, G. W., Deneyer, L., Desrosiers, M. Y., Diamant, Z., et al. (2019) · Allergy · doi:10.1111/all.13875 · Cited by 395 · see citing works
The global burden of chronic urticaria for the patient and society*
Gonçalo, M., Giménez-Arnau, A. M., Al-Ahmad, M. S., Ben‐Shoshan, M., Bernstein, J. A., Ensina, L. F., Fomina, D. S., Galván, C. A., Godse, K. V., Grattan, C. E. H., et al. (2020) · British Journal of Dermatology · doi:10.1111/bjd.19561 · Cited by 387 · see citing works
Self-citationEffect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks
Banerji, A., Riedl, M. A., Bernstein, J. A., Cicardi, M., Longhurst, H. J., Zuraw, B. L., Busse, P. J., Anderson, J. T., Magerl, M. A. K., Martinez‐Saguer, I., et al. (2018) · JAMA · doi:10.1001/jama.2018.16773 · Cited by 321 · see citing works
Self-citationUrticaria: Collegium Internationale Allergologicum (CIA) Update 2020
Maurer, M., Eyerich, K., Eyerich, S., Ferrer, M., Gutermuth, J., Hartmann, K., Jakob, T., Kapp, A., Kolkhir, P., Larenas‐Linnemann, D. E., et al. (2020) · International Archives of Allergy and Immunology · doi:10.1159/000507218 · Cited by 186 · see citing works
Self-citationSánchez‐Borges, M., Ansotegui, I. J., Baiardini, I., Bernstein, J., Canonica, G. W., Ebisawa, M., Gómez, M. R., Díaz, S. N. G., Martin, B. L., Morais‐Almeida, M., et al. (2021) · World Allergy Organization Journal · doi:10.1016/j.waojou.2021.100533 · Cited by 138 · see citing works
Breiteneder, H., Diamant, Z., Eiwegger, T., Fokkens, W. J., Traidl‐Hoffmann, C., Nadeau, K. C., O’Hehir, R. E., O’Mahony, L., Pfaar, O., Torres, M. J., et al. (2019) · Allergy · doi:10.1111/all.13851 · Cited by 107 · see citing works
Bygum, A., Busse, P. J., Caballero, T., & Maurer, M. (2017) · Frontiers in Medicine · doi:10.3389/fmed.2017.00212 · Cited by 88 · see citing works
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Türk, M., Carneiro‐Leão, L., Kolkhir, P., Bonnekoh, H., Buttgereit, T., & Maurer, M. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.07.021 · Cited by 78 · see citing works
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Maurer, M., Raap, U., Staubach, P., Richter‐Huhn, G., Bauer, A., Oppel, E. M., Hillen, U., Baeumer, D., Reinhardt, M., & Chapman‐Rothe, N. (2019) · Clinical & Experimental Allergy · doi:10.1111/cea.13309 · Cited by 74 · see citing works
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Maurer, M., Giménez‐Arnau, A. M., Ensina, L. F., Chu, C., Jaumont, X., & Tassinari, P. A. (2020) · World Allergy Organization Journal · doi:10.1016/j.waojou.2020.100460 · Cited by 62 · see citing works
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Brand, C. J. (1989) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1989.195.11.1531 · Cited by 52 · see citing works
Ghazanfar, M. N., Holm, J. G., & Thomsen, S. F. (2018) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15045 · Cited by 49 · see citing works
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Wagner, N., Zink, A., Hell, K., Reinhardt, M., Romer, K., Hillmann, E., Baeumer, D., & Schielein, M. C. (2021) · Dermatology and Therapy · doi:10.1007/s13555-021-00537-5 · Cited by 41 · see citing works
Rubini, N., Ensina, L. F., da Silva, E. M. K., Sano, F., & Solé, D. (2019) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2019.05.003 · Cited by 38 · see citing works
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Xu, X., Ong, Y. K., & Wang, D. Y. (2019) · Allergy · doi:10.1111/all.14044 · Cited by 35 · see citing works
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Agosta, E. D., Salvati, L., Corazza, M., Baiardini, I., Ambrogio, F., Angileri, L., Antonelli, E., Belluzzo, F., Bonamonte, D., Bonzano, L., et al. (2021) · Clinical and Molecular Allergy · doi:10.1186/s12948-021-00165-6 · Cited by 34 · see citing works
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Vyas, J., Johns, J. R., Ali, F. M., Singh, R., Ingram, J. R., Salek, S., & Finlay, A. Y. (2023) · British Journal of Dermatology · doi:10.1093/bjd/ljad079 · Cited by 28 · see citing works
Lapeere, H., Baeck, M., Stockman, A., Sabato, V., Grosber, M., Moutschen, M. P., Lambert, J., Vandebuerie, L., de Montjoye, L., Rabijns, H., et al. (2019) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15684 · Cited by 26 · see citing works
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Self-citationKatelaris, C. H., Lima, H., Marsland, A. M., Weller, K., Shah, A. A., & Waserman, S. (2021) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2021.02.026 · Cited by 25 · see citing works
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Can, P. K., Değirmentepe, E. N., Etikan, P., Kızıltaç, K., Gelincik, A. A., Demir, S., Büyüköztürk, S., Haşal, E., Başkan, E. B., Aydın, Ö., et al. (2021) · World Allergy Organization Journal · doi:10.1016/j.waojou.2021.100554 · Cited by 22 · see citing works
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Can, P. K., Etikan, P., Değirmentepe, E. N., & Kocatürk, E. (2021) · Asian Pacific Journal of Allergy and Immunology · doi:10.12932/ap-180920-0965 · Cited by 14 · see citing works
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Manzoor, H., Razi, F., Rasheed, A., Sarfraz, Z., Sarfraz, A., Robles‐Velasco, K., Félix, M., & Chérrez-Ojeda, I. (2022) · Healthcare · doi:10.3390/healthcare10122579 · Cited by 14 · see citing works
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Self-citationSeetasith, A., Holden, M., Hetherington, J., Keal, A., Salmon, P., Bernstein, J. A., & Casale, T. B. (2024) · Current Medical Research and Opinion · doi:10.1080/03007995.2024.2354534 · Cited by 9 · see citing works
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Kruglova, L. S. (2019) · Medical alphabet · doi:10.33667/2078-5631-2019-2-26(401)-15-20 · Cited by 2 · see citing works
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Ye, Y. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.97226 · Cited by 1 · see citing works
Tajerian, A., Pourvali, A., Khoshkhui, M., Aliabadi, M. M., Mobinikhaledi, M., & Faridzadeh, A. (2024) · Archives of Dermatological Research · doi:10.1007/s00403-024-03629-2 · Cited by 1 · see citing works
Predictors of Super/Poor Omalizumab Response in Chinese Refractory Chronic Spontaneous Urticaria
Chen, A., Yang, H., Yang, X., Huang, X., Li, S., Deng, S., Wang, H., Song, Z., & Chen, Q. (2026) · Dermatology · doi:10.1159/000551762 · Cited by 1 · see citing works
Surfactant Protein D: A Therapeutic Target for Allergic Airway Diseases
Singh, I., Beirag, N., Kishore, U., & Shamji, M. H. (2021) · Springer eBooks · doi:10.1007/978-3-030-67048-1_6 · Cited by 1 · see citing works
Qin, H., Xiao, X., Qin, D., Cao, W., Wang, L., Xi, M., Zou, Z., Yang, Q., Chen, S., Liu, H., et al. (2024) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1155/2024/8202476 · Cited by 1 · see citing works
Kutlu, Ö., Karaarslan, E., Karaosmanoğlu, N., & Ekşioğlu, M. (2019) · International Journal of Scientific Reports · doi:10.18203/issn.2454-2156.intjscirep20195299 · Cited by 1 · see citing works
Impact of Chronic Urticaria and How to Measure It
Weller, K. (2021) · Springer eBooks · doi:10.1007/978-3-030-84574-2_4 · Cited by 1 · see citing works
Self-citationWeller, K., Staubach, P., Metz, M., Chapman‐Rothe, N., Sieder, C., Bräutigam, M., & Maurer, M. (2018) · SKIN The Journal of Cutaneous Medicine · doi:10.25251/skin.2.supp.53
Self-citationEfficacy of omalizumab for extracutaneous symptoms of chronic spontaneous urticaria
Belbézier, A., Boccon‐Gibod, I., & Bouillet, L. (2021) · European Journal of Dermatology · doi:10.1684/ejd.2020.3717
The Role of Anti-IgE Antibodies in Urticaria
Pepe, P., & Mandel, V. D. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.97025
Omalizumab for the treatment of chronic spontaneous urticaria: a systematic review
Rao, N. G., Jing, H. X., Kabir, A. R., & Surthi, R. (2021) · International Journal of Research in Dermatology · doi:10.18203/issn.2455-4529.intjresdermatol20214213
Grattan, C. E. H., & Saini, S. S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-80912-2.00010-x
Yücel, M. B. (2026) · European Annals of Allergy and Clinical Immunology · doi:10.23822/eurannaci.1764-1489.460
- Authors
- Staubach, P., Metz, M., Chapman‐Rothe, N., Sieder, C., Bräutigam, M., Maurer, M., & Weller, K.
- Affiliations
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Charité – Universitätsmedizin Berlin (DE)
- Novartis (Switzerland) (CH)
- Novartis (Germany) (DE)
- Corresponding author
- Weller, K.
- Venue
- Allergy
- Publisher
- Wiley
- Published
- 2017-12-11
- Volume
- 73
- Issue
- 3
- Pages
- 576-584
- ISSN
- 0105-4538 (ISSN-L)
- 1398-9995
- PMC
- PMC5836932
- OpenAlex
- W2766150186
- Cited by
- 65
- References
- 31
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 8 · 2023: 3 · 2022: 7 · 2021: 18 · 2020: 5 · 2019: 13 · 2018: 7 · 2017: 1
- FWCI
- 6.21
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Allergy (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Refubium (Universitätsbibliothek der Freien Universität Berlin) (submittedVersion, cc-by-nc-nd)
- Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
- Funders
- Novartis Pharma
- Topics
- Health Sciences › Medicine › Rheumatology › Urticaria and Related Conditions
- Life Sciences › Immunology and Microbiology › Immunology › Mast cells and histamine
- Health Sciences › Medicine › Rheumatology › Eosinophilic Disorders and Syndromes
- Keywords
- omalizumab, chronic spontaneous urticaria, angioedema, quality of life, anti-IgE therapy, psychological well-being, Dermatology Life Quality Index
- MeSH terms
- Omalizumab, Adolescent, Adult, Aged, Angioedema, Double-Blind Method, Female, Humans, Male, Middle Aged, Quality of Life, Urticaria, Anti-Allergic Agents, Young Adult
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