Decreasing perinatal mortality in placental abruption
Open accessAbstract
OBJECTIVE: To study perinatal mortality associated with placental abruption. DESIGN: Retrospective population study using the Finnish Hospital Discharge Register and Medical Birth Register data. SETTING: Finland, 1987-2005. POPULATION: Pregnancies with placental abruption and all other births without placental abruption. METHODS: The national Hospital Discharge Register and Medical Birth Register were used to identify all pregnancies with placental abruption. Demographic data and delivery outcomes were collected retrospectively. Perinatal mortality associated with placental abruption was compared with that in other births. Potential risk factors were analysed. MAIN OUTCOME MEASURES: Perinatal mortality in placental abruption. RESULTS: The study consisted of 618 735 women with 1.14 million pregnancies, 4336 of whom had placental abruption. Overall perinatal mortality with abruption was 119 per 1000 births. Placental abruption explained 7% of all perinatal deaths. The mortality among singleton births (125 per 1000) was higher than among multiple births (40 per 1000). The majority of deaths (77%) occurred in utero. Singleton perinatal mortality with abruption decreased from 173 per 1000 in 1987-1990 to 98 per 1000 in 2000-2005 (p < 0.001). In singleton births at <32 gestational weeks, overall perinatal mortality was high (345 per 1000) and was not increased by placental abruption. Prematurity, low birthweight, male fetal sex and maternal smoking were independent risk factors for placental abruption-related perinatal mortality. CONCLUSIONS: Although mortality associated with placental abruption decreased during the study period, placental abruption still remains an important cause of perinatal mortality.
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Abruption complicates 0.6-1.2% of pregnancies.
“Abruption occurs in 0.6–1.2% of all pregnancies, with nearly half of abruption occurring at term gestations.”
From Placental abruption at near-term and term gestations: Pathophysiology, epidemiology, diagnosis, and management (2023) · cites this paper as [7]
The Introduction reports that placental abruption occurs in 0.4–1.4% of pregnancies, supporting the general frequency claim but not the stated 0.6–1.2% range. The Results report an incidence of 3.8 per 1,000 deliveries in this study. Page numbers are unavailable in our copy. (LLM, conf=0.88)
Experimental — accuracy not yet measuredApproximately half of abruption occurs at term gestations.
“with nearly half of abruption occurring at term gestations.”
From Placental abruption at near-term and term gestations: Pathophysiology, epidemiology, diagnosis, and management (2023) · cites this paper as [7]
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Cites
Perinatal complications associated with maternal tobacco use
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Self-citationQuality of data on subsequent events in a routine Medical Birth Register
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Cited by
Sorted by citations
Severe placental abruption: clinical definition and associations with maternal complications
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Neurodevelopmental outcomes in children in relation to placental abruption
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- Authors
- TIKKANEN, M., LUUKKAALA, T., GISSLER, M., RITVANEN, A., YLIKORKALA, O., PAAVONEN, J., NUUTILA, M., ANDERSSON, S., & METSÄRANTA, M.
- Affiliations
- University of Helsinki (FI)
- Pirkanmaa Hospital District (FI)
- Finnish Institute for Health and Welfare (FI)
- Corresponding author
- METSÄRANTA, MARJO
- Venue
- Acta Obstetricia Et Gynecologica Scandinavica
- Publisher
- Wiley
- Published
- 2012-12-05
- Volume
- 92
- Issue
- 3
- Pages
- 298-305
- ISSN
- 0001-6349 (ISSN-L)
- 1600-0412
- OpenAlex
- W2157709359
- Cited by
- 80
- References
- 17
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 3 · 2020: 12 · 2019: 5 · 2018: 7 · 2017: 8 · 2016: 3 · 2015: 6 · 2014: 7 · 2013: 4
- FWCI
- 4.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Acta Obstetricia Et Gynecologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
- Funders
- Helsingin ja Uudenmaan Sairaanhoitopiiri
- Suomen Lääketieteen Säätiö
- Päivikki ja Sakari Sohlbergin Säätiö
- Medical Research Council (MR/K006525/1)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- placental abruption, perinatal mortality, fetal death, risk factors, preterm birth, low birth weight, fetal sex, maternal smoking, multiple births, singleton births, mortality trends
- MeSH terms
- Abruptio Placentae, Adult, Birth Weight, Female, Finland, Gestational Age, Humans, Infant, Newborn, Male, Pregnancy, Pregnancy, Multiple, Retrospective Studies, Risk Factors, Sex Factors, Smoking, Multivariate Analysis, Premature Birth, Perinatal Mortality, Young Adult
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