Review article: the economic impact of the irritable bowel syndrome

Canavan, C.; West, J.; Card, T.

doi:10.1111/apt.12938

Cited by 458Gastrointestinal motility and disordersHealth Systems, Economic Evaluations, Quality of LifeChronic Disease Management Strategies

Review article: the economic impact of the irritable bowel syndrome

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Canavan, C., West, J., Card, T.·2014·Alimentary Pharmacology & Therapeutics

DOI 10.1111/apt.12938

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Abstract

BACKGROUND: Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal system affecting a large number of people worldwide. Whilst it has no attributable mortality, it has substantial impact on patients' quality of life (QoL) and is associated with considerable healthcare resource use. AIM: To review the economic impact of IBS, firstly on the individual, secondly on healthcare systems internationally and thirdly to society. METHODS: Appropriate databases were searched for relevant papers using the terms: Irritable Bowel Syndrome; IBS; irritable colon; functional bowel/colonic disease; economics; health care/service costs; health expenditure/resources; health care/service utilisation; productivity. RESULTS: Irritable bowel syndrome impacts most substantially on patients' work and social life. Reduction in QoL is such that on average patients would sacrifice between 10 and 15 years of their remaining life expectancy for an immediate cure. Between 15% and 43% of patients pay for remedies. No studies quantify loss of earnings related to IBS. Direct care costs are substantial; 48% of patients incur some costs in any year with annual international estimates per patient of: USA $742-$7547, UK £90-£316, France €567-€862, Canada $259, Germany €791, Norway NOK 2098 (€262) and Iran $92. Minimising extensive diagnostic investigations could generate savings and has been shown as not detrimental to patients. Cost to industry internationally through absenteeism and presenteeism related to IBS is estimated between £400 and £900 per patient annually. CONCLUSIONS: Irritable bowel syndrome is associated with substantial costs to patients, healthcare systems and society. Considerable benefit could be obtained from effective interventions.

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Authors: Canavan, C., West, J., & Card, T.
Affiliations: University of Nottingham (GB)
Corresponding author: Canavan, C.
ORCID: West, J.
Card, T.
Venue: Alimentary Pharmacology & Therapeutics
Publisher: Wiley
Published: 2014-09-09
Volume: 40
Issue: 9
Pages: 1023-1034
ISSN: 0269-2813 (ISSN-L)
DOI: 10.1111/apt.12938
OpenAlex: W2017092019
Cited by: 458
References: 68
Citations by year: 2026: 26 · 2025: 33 · 2024: 49 · 2023: 42 · 2022: 44 · 2021: 55 · 2020: 45 · 2019: 41 · 2018: 34 · 2017: 40 · 2016: 22 · 2015: 26 · 2014: 1
FWCI: 4.85
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 357 d)
Locations: Alimentary Pharmacology & Therapeutics (publishedVersion)
PubMed (publishedVersion)
Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
Nottingham ePrints (University of Nottingham) (submittedVersion, cc-by)
Funders: Medical Research Council (G1002360)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
Keywords: irritable bowel syndrome, economic burden, health care costs, quality of life, productivity loss, absenteeism, presenteeism, health care utilization, out-of-pocket costs
MeSH terms: Absenteeism, Chronic Disease, Delivery of Health Care, Health Expenditures, Health Resources, Humans, Life Expectancy, Quality of Life, Health Care Costs, Internationality, Irritable Bowel Syndrome

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