The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure
Open accessAbstract
Summary: Mitochondria not only supply the energy for cell function, but also take part in cell signaling. This review describes the dysfunctions of mitochondria in aging and neurodegenerative diseases, and the signaling pathways leading to mitochondrial biogenesis (including PGC‐1 family proteins, SIRT1, AMPK) and mitophagy (parkin‐Pink1 pathway). Understanding the regulation of these mitochondrial pathways may be beneficial in finding pharmacological approaches or lifestyle changes (caloric restrict or exercise) to modulate mitochondrial biogenesis and/or to activate mitophagy for the removal of damaged mitochondria, thus reducing the onset and/or severity of neurodegenerative diseases.
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1 retracted
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Cited by
Kumar, V., Kundu, S., Singh, A., & Singh, S. (2022) · Current Neuropharmacology · doi:10.2174/1570159x19666210609160017 · Cited by 210
Chidambaram, S. B., Essa, M. M., Rathipriya, A. G., Bishir, M., Ray, B., Mahalakshmi, A. M., Tousif, A. H., Sakharkar, M. K., Kashyap, R. S., Friedland, R. P., et al. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.107988 · Cited by 204
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes
Ignatenko, O., Malinen, S., Rybas, S., Vihinen, H., Nikkanen, J., Kononov, A., Jokitalo, E. S., Ince-Dunn, G., & Suomalainen, A. (2023) · Journal of Cell Biology · doi:10.1083/jcb.202203019 · Cited by 63
Liu, X., Shen, L., Wan, M., Xie, H., & Wang, Z. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02428-1 · Cited by 33
The role of microRNA-485 in neurodegenerative diseases
Ryu, I. S., Kim, D. H., Cho, H.-J., & Ryu, J.-H. (2023) · Reviews in the Neurosciences · doi:10.1515/revneuro-2022-0039 · Cited by 25
Metadata
- Authors
- Wang, Y., Xu, E., Musich, P. R., & Lin, F.
- Venue
- CNS Neuroscience & Therapeutics
- Publisher
- Wiley
- Published
- 2019-03-19
- Volume
- 25
- Issue
- 7
- Pages
- 816-824
- ISSN
- 1755-5930 (ISSN-L)
- 1755-5949
- OpenAlex
- W2922573905
- Cited by
- 294
- References
- 105
- FWCI
- 8.24
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wang, Y., Xu, E., Musich, P. R., & Lin, F. (2019). Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. CNS Neuroscience & Therapeutics. https://doi.org/10.1111/cns.13116
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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