The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Interventions for people at ultra‐high risk for psychosis: A systematic review of economic evaluations
Abstract
Aim Psychotic disorders have long-term negative consequences for functioning and quality of life. Ultra-high risk (UHR) programs aim to identify and treat people during the prodromal period before their first psychotic episode. Though studies on the clinical effectiveness of treating prodromal symptoms in people at UHR for psychosis exist, no review has exclusively and comprehensively evaluated the economic impact of UHR programs. Our objective was to systematically review the literature on economic evaluations of UHR programs. Methods We searched the Cochrane, EMBASE, MEDLINE, and PsycInfo electronic databases, in addition to grey literature, from inception to March 2020 to identify economic evaluations of UHR programs. We included all cost and cost-effectiveness studies of interventions for people at UHR. The data were synthesized qualitatively, and a risk of bias assessment was performed. Results Of the 1916 articles retrieved, six studies met our inclusion criteria. These included three cost analysis studies and three cost-effectiveness studies. Five studies were conducted from the health system perspective and the time horizon varied between six months and ten years. Only two reported quality-adjusted life-years (QALYs) as their outcome. Overall, all cost-effectiveness studies and one cost analysis suggested that UHR programs were cost-effective and cost saving, respectively. The risk of bias assessment suggested moderate levels of bias across all studies. Conclusion Eco…
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Evidence consistently shows cost-effectiveness of early interventions in psychosis across different health systems.
“Evidence consistently shows cost-effectiveness of early interventions in psychosis across different health systems.”
From The Lancet Psychiatry Commission on youth mental health (2024) · cites this paper as [416]
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The Lancet Psychiatry Commission on youth mental health
McGorry, P. D., Mei, C., Dalal, N., Alvarez-Jimenez, M., Blakemore, S.-J., Browne, V., Dooley, B., Hickie, I. B., Jones, P. B., McDaid, D., et al. (2024) · The Lancet Psychiatry · doi:10.1016/s2215-0366(24)00163-9 · Cited by 663
Metadata
- Authors
- Ologundudu, O. M., Lau, T., Palaniyappan, L., Ali, S., & Anderson, K. K.
- Affiliations
- Western University (CA)
- Corresponding author
- Anderson, Kelly K.
- Venue
- Early Intervention in Psychiatry
- Publisher
- Wiley
- Published
- 2020-10-12
- Volume
- 15
- Issue
- 5
- Pages
- 1115-1126
- ISSN
- 1751-7885 (ISSN-L)
- 1751-7893
- OpenAlex
- W3092639110
- Cited by
- 10
- References
- 4
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 1
- FWCI
- 0.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Early Intervention in Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Scholarship@Western (Western University) (submittedVersion)
- Funders
- Western University
- Canadian Institutes of Health Research (153022)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- clinical high risk for psychosis, early intervention programs, economic evaluation, cost-effectiveness, cost analysis, quality-adjusted life years, risk of bias, health system perspective
- MeSH terms
- Cost-Benefit Analysis, Humans, Psychotic Disorders, Quality of Life, Quality-Adjusted Life Years, Prodromal Symptoms
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