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The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.

Guided bone regeneration: materials and biological mechanisms revisited

Open access
Elgali, Ibrahim, Omar, Omar, Dahlin, Christer, Thomsen, Peter·2017·European Journal of Oral Sciences

Abstract

Guided bone regeneration (GBR) is commonly used in combination with the installment of titanium implants. The application of a membrane to exclude non‐osteogenic tissues from interfering with bone regeneration is a key principle of GBR. Membrane materials possess a number of properties which are amenable to modification. A large number of membranes have been introduced for experimental and clinical verification. This prompts the need for an update on membrane properties and the biological outcomes, as well as a critical assessment of the biological mechanisms governing bone regeneration in defects covered by membranes. The relevant literature for this narrative review was assessed after a MEDLINE/PubMed database search. Experimental data suggest that different modifications of the physicochemical and mechanical properties of membranes may promote bone regeneration. Nevertheless, the precise role of membrane porosities for the barrier function of GBR membranes still awaits elucidation. Novel experimental findings also suggest an active role of the membrane compartment per se in promoting the regenerative processes in the underlying defect during GBR, instead of being purely a passive barrier. The optimization of membrane materials by systematically addressing both the barrier and the bioactive properties is an important strategy in this field of research.

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Metadata

Authors
Elgali, I., Omar, O., Dahlin, C., & Thomsen, P.
Venue
European Journal of Oral Sciences
Publisher
Wiley
Published
2017-08-19
Volume
125
Issue
5
Pages
315-337
ISSN
  • 0029-845X (ISSN-L)
  • 0909-8836
  • 1600-0722
OpenAlex
W2749131763
Cited by
848
References
83
FWCI
48.19
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Guided bone regeneration: materials and biological mechanisms revisited. https://app.cochat.ai/papers/10.1111/eos.12364
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Elgali, I., Omar, O., Dahlin, C., & Thomsen, P. (2017). Guided bone regeneration: materials and biological mechanisms revisited. European Journal of Oral Sciences. https://doi.org/10.1111/eos.12364

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