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Cited by 116Dermatology and Skin DiseasesSkin Protection and AgingOral microbiology and periodontitis research

Ultraviolet radiation, both UVA and UVB , influences the composition of the skin microbiome

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Burns, Erin M., Ahmed, Hana, Isedeh, Prescilia N., Kohli, Indermeet, Van Der Pol, William, Shaheen, Abdullah, Muzaffar, Anum F., Al‐Sadek, Camli +9 more·2019·Experimental Dermatology
DOI 10.1111/exd.13854PMC PMC7394481
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Abstract

Background: Studies have begun to investigate the complex relationship between host and microorganisms in non‐infectious pathologies such as acne, atopic dermatitis and psoriasis. Though the skin is exposed to environmental stressors such as ultraviolet radiation ( UVR ), no studies exist examining the effects of both UVA and UVB on the skin microbiome. Objective: To test the effect of UVA and UVB on human skin microbiome. Methods: To test whether UV will alter the cutaneous microbiome, participants were exposed to doses of UVA (22‐47 J/cm 2 ) or UVB (100‐350 mJ /cm 2 ) and samples were collected. DNA was isolated and sequenced to identify the microbial composition of each sample. Results: There was vast intra‐ and inter‐subject variation at all time points, and phylum and species‐level differences were identified. These included an increase in the phylum Cyanobacteria and a decrease in the family Lactobacillaceae and Pseudomonadaceae. The sensitivity of microbes to UVR and their re‐colonization potential following exposure differed in UVA vs UVB samples. Limitations: The sample size was small, and the study was limited to males. Conclusion: The results demonstrate that UVR has profound qualitative and quantitative influences on the composition of the skin microbiome, possibly effecting skin pathology in which UVR is a factor.

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  • UV-A and UV-B exposure has an impact on the composition of the skin microbiota, with a decrease in the family Lactobacillaceae and Pseudomonadaceae while the phylum Cyanobacteria increased following ultraviolet radiation exposure.

    “This finding was based on the 16S rDNA sequencing and reveals a decrease in the family Lactobacillaceae and Pseudomonadaceae while the phylum Cyanobacteria increased following ultraviolet radiation exposure (Burns et al. 2019).”

    From Skin protection from solar ultraviolet radiation using natural compounds: a review (2024) · cites this paper as Burns et al. 2019

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Research works printed but not linked: 27

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Authors
Burns, E. M., Ahmed, H., Isedeh, P. N., Kohli, I., Van Der Pol, W., Shaheen, A., Muzaffar, A. F., Al‐Sadek, C., Foy, T. M., Abdelgawwad, M. S., Huda, S., Lim, H. W., Hamzavi, I., Bae, S., Morrow, C. D., Elmets, C. A., & Yusuf, N.
Affiliations
  • University of Alabama at Birmingham (US)
  • Florida State University (US)
  • Henry Ford Health (US)
  • Center for Clinical and Translational Science UAB Birmingham Alabama
Corresponding author
Yusuf, Nabiha
ORCID
Venue
Experimental Dermatology
Publisher
Wiley
Published
2019-01-14
Volume
28
Issue
2
Pages
136-141
ISSN
  • 0906-6705 (ISSN-L)
  • 1600-0625
DOI
10.1111/exd.13854
PMC
PMC7394481
OpenAlex
W2902118331
Cited by
116
References
0
Citations by year
2026: 12 · 2025: 19 · 2024: 30 · 2023: 16 · 2022: 14 · 2021: 14 · 2020: 8 · 2019: 2 · 2018: 1
FWCI
6.77
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Experimental Dermatology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • University of Alabama at Birmingham
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (1R01AR071157‐01A1)
  • National Institutes of Health
  • Comprehensive Cancer Center, University of Alabama at Birmingham (P30 CA013148, UL1TR001417)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Keywords
ultraviolet radiation, UVA, UV-B radiation, skin microbiome, microbial community composition, cyanobacteria, Lactobacillaceae, Pseudomonadaceae, host-microbe interactions, skin diseases
MeSH terms
Acne Vulgaris, Adult, Dermatitis, Atopic, DNA, Humans, Inflammation, Male, Psoriasis, Skin, Ultraviolet Rays, Young Adult, Microbiota

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