Endoplasmic reticulum stress signalling-from basic mechanisms to clinical applications
Almanza, Aitor, Carlesso, Antonio, Chintha, Chetan, Creedican, Stuart, Doultsinos, Dimitrios, Leuzzi, Brian, Luís, Andreia, McCarthy, Nicole +17 more·2019·The FEBS Journal
Cites (395)
Items 201–395 of 395
- GRP94, an ER chaperone with protein and peptide binding propertiesYair Argon, Birgitte B. Simen · 1999 · Seminars in Cell and Developmental Biology
- The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiologyRie Asada, Soshi Kanemoto, Shinichi Kondo, Atsushi Saito, K. Imaizumi · 2011 · The Journal of Biochemistry
- Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitorsLikun Wang, B. Gayani K. Perera, Sanjay B. Hari, Barun Bhhatarai, Bradley J. Backes, Markus A. Seeliger, Stephan C. Schürer, Scott A. Oakes, Feroz R. Papa, Dustin J. Maly · 2012 · Nature Chemical Biology
- A Novel Quality Control Compartment Derived from the Endoplasmic ReticulumShiri Kamhi-Nesher, Marina Shenkman, Sandra Tolchinsky, Sharon Vigodman Fromm, Rachel L. Ehrlich, Gerardo Zelmar Lederkremer · 2001 · Molecular Biology of the Cell
- P38 MAPK REGULATED XBP1s NUCLEAR TRANSLOCATION AND mRNA STABILITY ARE CRUCIAL FOR MAINTENANCE OF GLUCOSE HOMEOSTASIS IN OBESITYCheng Sun, Jaemin Lee, Ying-Jiang Zhou, Justin Lee, Deniz Gokalp, H. Herrema, S. Park, R. Davis, U. Ozcan · 2011 · Nature Medicine
- The ER stress transducer IRE1β is required for airway epithelial mucin productionMary B. Martino, L Jones, Brian K. Brighton, Camille Ehré, L Abdulah, C. William Davis, David Ron, Wanda K. O’Neal, Carla M. P. Ribeiro · 2012 · Mucosal Immunology
- Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1R. Luke Wiseman, Yuhong Zhang, Kenneth Pak Kin Lee, Heather P. Harding, Cole M. Haynes, Joshua L. Price, Frank Sicheri, David Ron · 2010 · Molecular Cell
- The Role of IRE1α in the Degradation of Insulin mRNA in Pancreatic β-CellsKathryn L. Lipson, Rajarshi Ghosh, Fumihiko Urano · 2008 · PLoS ONE
- Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicingMasaki Ri, Etsu Tashiro, Daisuke Oikawa, Satoko Shinjo, Mio Tokuda, Yumi Yokouchi, T Narita, A Masaki, Asahi Ito, J Ding et al. · 2012 · Blood Cancer Journal
- Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral SclerosisHan-Jou Chen, Georgia Anagnostou, Andrea Chai, James Withers, Alex G. Morris, Jason Adhikaree, Giuseppa Pennetta, Jacqueline de Belleroche · 2010 · Journal of Biological Chemistry
- Interaction of ATF6 and serum response factorCheng Zhu, Finn‐Eirik Johansen, Ron Prywes · 1997 · Molecular and Cellular Biology
- Evidence for role of glycoprotein carbohydrates in membrane transport: specific inhibition by tunicamycin.Kenneth Olden, Robert M. Pratt, C. Jaworski, Kenneth M. Yamada · 1979 · Proceedings of the National Academy of Sciences
- Defects in IRE1 enhance cell death and fail to degrade mRNAs encoding secretory pathway proteins in the Arabidopsis unfolded protein responseKei‐ichiro Mishiba, Yukihiro Nagashima, Eiji Suzuki · 2013 · Proceedings of the National Academy of Sciences
- Redox controls UPR to control redoxDavide Eletto, Éric Chevet, Yair Argon, Christian Appenzeller‐Herzog · 2014 · Journal of Cell Science
- Dual IRE1 RNase functions dictate glioblastoma developmentStéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan et al. · 2018 · EMBO Molecular Medicine
- The transcription factor XBP1 is selectively required for eosinophil differentiationSarah Bettigole, R. Lis, S. Adoro, Ann-Hwee Lee, Lisa A. Spencer, Peter F. Weller, Laurie H. Glimcher · 2015 · Nature Immunology
- ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of AsthmaMarina Miller, Peter Rosenthal, Andrew Beppu, James L Mueller, Hal M. Hoffman, Arvin B. Tam, Taylor Alan Doherty, Matthew D. McGeough, Carla A. Peña, Maho Suzukawa et al. · 2014 · The Journal of Immunology
- Mdm1/Snx13 is a novel ER–endolysosomal interorganelle tethering proteinW. Mike Henne, Lu Zhu, Zsolt Balogi, Christopher J. Stefan, Jeffrey A. Pleiss, Scott D. Emr · 2015 · The Journal of Cell Biology
- Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injuryBéatrice Bailly‐Maitre, Constantino Fondevila, Fady M. Kaldas et al. · 2006 · Proceedings of the National Academy of Sciences
- Cotranslational Targeting of XBP1 Protein to the Membrane Promotes Cytoplasmic Splicing of Its Own mRNAKota Yanagitani, Yusuke Imagawa, Takao Iwawaki, Akira Hosoda, Michiko Saito, Yukio Kimata, Kenji Kohno · 2009 · Molecular Cell
- Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductaseYoungah Jo, Russell A. DeBose‐Boyd · 2010 · Critical Reviews in Biochemistry and Molecular Biology
- Identification of a consensus element recognized and cleaved by IRE1αDaisuke Oikawa, Mio Tokuda, Akira Hosoda · 2010 · Nucleic Acids Research
- Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1αDenisse Sepúlveda, Diego Rojas‐Rivera, Diego A. Rodríguez, Jody Groenendyk, Andrés Kohler, Cynthia Lebeaupin, Shinya Ito, Hery Urra, Amado Carreras‐Sureda, Younis Hazari et al. · 2018 · Molecular Cell
- The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasisPhilipp Kimmig, Marcy Diaz, Jiashun Zheng, Christopher C. Williams, Alexander B. Lang, Tomás Aragón, Hao Li, Peter Walter · 2012 · eLife
- Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s–PPARα axis signallingMengle Shao, Bo Shan, Yang Liu, Yiping Deng, Yan Cheng, Ying Wu, Ting Mao, Yifu Qiu, Yubo Zhou, Shan Jiang et al. · 2014 · Nature Communications
- BiP binds type I procollagen pro alpha chains with mutations in the carboxyl-terminal propeptide synthesized by cells from patients with osteogenesis imperfecta.Chessler, S.D., Byers, P.H. · 1993 · Journal of Biological Chemistry
- Functional and morphological impact of ER stress on mitochondriaKayleen Vannuvel, Patricia Renard, Martine J. Raes, Thierry Arnould · 2013 · Journal of Cellular Physiology
- A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signallingValentina Gandin, Maura Pellei, Francesco Tisato, Marina Porchia, Carlo Santini, Cristina Marzano · 2011 · Journal of Cellular and Molecular Medicine
- Endoplasmic Reticulum Stress and Liver InjuryNeil Kaplowitz, Tin Aung Than, Masao Shinohara, Cheng Ji · 2007 · Seminars in Liver Disease
- Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt ActivationXukun Bi, Guangyu Zhang, Xiaoding Wang, Chau Nguyen, Herman I. May, Xiaoting Li, Ali Al‐Hashimi, Richard C. Austin, Thomas G. Gillette, Guosheng Fu et al. · 2018 · Circulation Research
- Preventing oxidative stress: a new role for XBP1Yuling Liu, M Adachi, Shiguang Zhao, Masato Hareyama, Albert C. Koong, Dan Luo, Thomas A. Rando, K Imai, Yasuhisa Shinomura · 2009 · Cell Death and Differentiation
- Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cellsSvetlana Saveljeva, S L Mc Laughlin, Peter Vandenabeele, Afshin Samali, Mathieu J.M. Bertrand · 2015 · Cell Death and Disease
- Functional ATPase Activity of p97/Valosin-containing Protein (VCP) Is Required for the Quality Control of Endoplasmic Reticulum in Neuronally Differentiated Mammalian PC12 CellsTaeko Kobayashi, Keiko Tanaka, Kiyoshi Inoue, Akira Kakizuka · 2002 · Journal of Biological Chemistry
- Regular physical activity prevents chronic pain by altering resident muscle macrophage phenotype and increasing interleukin-10 in miceAudrey S. Leung, Nicholas Scott Gregory, Lee‐Ann H. Allen, Kathleen Anne Sluka · 2015 · Pain
- The 78 kDa Glucose-Regulated Protein (GRP78/BIP) Is Expressed on the Cell Membrane, Is Released into Cell Culture Medium and Is Also Present in Human Peripheral CirculationAndrea Delpino, Mauro Castelli · 2002 · Bioscience Reports
- Amyotrophic Lateral Sclerosis Multiprotein Biomarkers in Peripheral Blood Mononuclear CellsGiovanni Nardo, Silvia Pozzi, Mauro Pignataro, Eliana Lauranzano, Giorgia Spano, Silvia Garbelli, Stefania Mantovani, Kalliopi Marinou, Laura Papetti, Marta Monteforte et al. · 2011 · PLoS ONE
- Phosphoregulation of Ire1 RNase splicing activityFilippo Prischi, Piotr R. Nowak, Marta Carrara, Maruf M. U. Ali · 2014 · Nature Communications
- Sphingolipids and mitochondrial apoptosisGauri Anand Patwardhan, Levi J. Beverly, Leah J. Siskind · 2015 · Journal of Bioenergetics and Biomembranes
- A Cluster of Thin Tubular Structures Mediates Transformation of the Endoplasmic Reticulum to Autophagic Isolation MembraneTakefumi Uemura, Masaya Yamamoto, Ai Kametaka, Yu‐shin Sou, Atsuko Yabashi, Akane Yamada, Hiromichi Annoh, Satoshi Kametaka, Masaaki Komatsu, Satoshi Waguri · 2014 · Molecular and Cellular Biology
- IRE1β Inhibits Chylomicron Production by Selectively Degrading MTP mRNAJahangir Iqbal, Kezhi Dai, Tracie A. Seimon, Rivka Jungreis, Miho Oyadomari, George Kuriakose, David Ron, Ira A. Tabas, M. Mahmood Hussain · 2008 · Cell Metabolism
- ATF4 Protein Deficiency Protects against High Fructose-induced Hypertriglyceridemia in MiceGuozhi Xiao, Ting Zhang, Shibing Yu, Sojin Lee, Virtu Calabuig-Navarro, Jun Yamauchi, Steven Ringquist, H. Henry Dong · 2013 · Journal of Biological Chemistry
- The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolismYingfeng Deng, Zhao V. Wang, Caroline Tao, Ningguo Gao, William L. Holland, Anwarul Ferdous, Joyce J. Repa, Guosheng Liang, Jin Ye, Mark A. Lehrman et al. · 2012 · Journal of Clinical Investigation
- Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stressCiara M Gallagher, Peter Walter · 2016 · eLife
- Type XVII collagen coordinates proliferation in the interfollicular epidermisMika Watanabe, Ken Natsuga, Wataru Nishie, Yasuaki Kobayashi, Giacomo Donati, Shotaro Suzuki, Yu Fujimura, Tadasuke Tsukiyama, Hideyuki Ujiie, Satoru Shinkuma et al. · 2017 · eLife
- Chemical Biology Investigation of Cell Death Pathways Activated by Endoplasmic Reticulum Stress Reveals Cytoprotective Modulators of ASK1Inki Kim, Chih‐Wen Shu, Wenjie Xu, Chung‐Wai Shiau, Daniel Grant, Stefan Vasile, Nicholas D. P. Cosford, John C. Reed · 2008 · Journal of Biological Chemistry
- Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosisLijun Wang, Brian Popko, Emily N. Tixier, Raymond P. Roos · 2014 · Neurobiology of Disease
- Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death ReceptorsRaffaella Iurlaro, Franziska Püschel, Clara Lucía León‐Annicchiarico, Hazel O’Connor, Séamus J. Martin, Daniel Palou-Gramón, Estefanía Lucendo, Cristina Muñoz‐Pinedo · 2017 · Molecular and Cellular Biology
- Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitorsMário Sanches, Nicole M. Duffy, Manisha Talukdar, N. Thevakumaran, David Chiovitti, Marella D. Canny, Kenneth Pak Kin Lee, Igor V. Kurinov, David Uehling, Rima Al‐awar et al. · 2014 · Nature Communications
- Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAsPierre Pirot, Najib Naamane, Frédérick Libert, Nils E. Magnusson, Torben Falck Orntoft, Alessandra Kupper Cardozo, Decio Laks Eizirik · 2007 · Diabetologia
- Eukaryotic initiation complex formation. Evidence for two distinct pathwaysSL Adams, B Safer, W. French Anderson · 1975 · Journal of Biological Chemistry
- Ligand-independent activation of estrogen receptor by XBP-1Lei Ding · 2003 · Nucleic Acids Research
- Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos.S J Ono, Hsiou‐Chi Liou, Ruth Davidon · 1991 · Proceedings of the National Academy of Sciences
- Endoplasmic Reticulum Stress-Induced Activation of Activating Transcription Factor 6 Decreases Insulin Gene Expression via Up-Regulation of Orphan Nuclear Receptor Small Heterodimer PartnerHye-Young Seo, Yong Deuk Kim, Kyeong‐Min Lee, Ae-Kyung Min, Mi-Kyung Kim, Hye‐Soon Kim, Kyu Chang Won, Joong‐Yeol Park, Ki-Up Lee, Hueng-Sik Choi et al. · 2008 · Endocrinology
- Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein responseNobuhiko Hiramatsu, Carissa Messah, Jaeseok Han, Matthew M. LaVail, Randal J. Kaufman, Jonathan H. Lin · 2014 · Molecular Biology of the Cell
- Inhibition of proteasome activity by the dietary flavonoid apigenin is associated with growth inhibition in cultured breast cancer cells and xenograftsDi Chen, Kristin R. Landis‐Piwowar, Marina S. Chen, Q. Ping Dou · 2007 · Breast Cancer Research
- XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic ReticulumWon Jae Huh, Emel Esen, Jessica H. Geahlen, Andrew J. Bredemeyer, Ann–Hwee Lee, Guanglu Shi, Stephen F. Konieczny, Laurie H. Glimcher, Jason C. Mills · 2010 · Gastroenterology
- PERK Is Required in the Adult Pancreas and Is Essential for Maintenance of Glucose HomeostasisYan Gao, Daniel J. Sartori, Changhong Li, Qian‐Chun Yu, Jake A. Kushner, Marie Celeste Simon, John Alan Diehl · 2012 · Molecular and Cellular Biology
- Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.C. Rubio-Patiño, J. P. Bossowski, G. D. de Donatis, L. Mondragón, E. Villa, L. Aira, J. Chiche, R. Mhaidly, C. Lebeaupin, S. Marchetti et al. · 2018 · Cell Metabolism
- Emerging roles for XBP1, a sUPeR transcription factorYin He, Sheng-Yi Sun, Hai-Bo Sha, Ziying Liu, Liu Yang, Zhen Xue, Hui Chen, Ling Qi · 2010 · Gene Expression
- ERAD substrates: Which way out?Daniel N. Hebert, Riccardo Bernasconi, Maurizio Molinari · 2009 · Seminars in Cell and Developmental Biology
- p23, a simple protein with complex activitiesSara J. Felts, David O. Toft · 2003 · Cell Stress and Chaperones
- Interference with glycosylation of glycoproteins. Inhibition of formation of lipid-linked oligosaccharides in vivoRoelf DATEMA, Ralph Τ. Schwarz · 1979 · Biochemical Journal
- Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulumAlexander S. McQuiston, John Alan Diehl · 2017 · F1000Research
- Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA.Heidemarie Ernst, Roger F. Duncan, J W Hershey · 1987 · Journal of Biological Chemistry
- Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1uChia‐yi Chen, Nicole S. Malchus, Beate Hehn, Walter Stelzer, Dönem Avci, Dieter Langosch, Marius K. Lemberg · 2014 · The EMBO Journal
- A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ERShahzad A. Siddiqi, Shahzad Siddiqi, Umair Saleem · 2010 · Journal of Lipid Research
- Tauroursodeoxycholate (TUDCA), chemical chaperone, enhances function of islets by reducing ER stressYeon Yi Lee, Shin Hee Hong, Ye Jin Lee, Sung Soo Chung, Hye Seung Jung, Sang Gyu Park, Kyong Soo Park · 2010 · Biochemical and Biophysical Research Communications
- Involvement of endoplasmic reticulum stress in the necroptosis of microglia/macrophages after spinal cord injuryHong Fan, H.-B. Tang, J. Kang, Lequn Shan, Hong Song, K. Zhu, J. Wang, Gong Ju, Yougang Wang · 2015 · Neuroscience
- XBP1 induces snail expression to promote epithelial- to-mesenchymal transition and invasion of breast cancer cellsHaiyu Li, Xingfeng Chen, Yue Gao, Jiayan Wu, Fan Zeng, Fangzhou Song · 2014 · Cellular Signalling
- The neuroprotective effects of cordycepin inhibit glutamate-induced oxidative and ER stress-associated apoptosis in hippocampal HT22 cellsMEI LING JIN, Sun Young Park, Young Hun Kim · 2014 · NeuroToxicology
- RtcB, a Novel RNA Ligase, Can Catalyze tRNA Splicing and HAC1 mRNA Splicing in VivoNaoko Tanaka, Birthe Meineke, Stewart Shuman · 2011 · Journal of Biological Chemistry
- Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stressK Rajesh, Jothilatha Krishnamoorthy, Urszula Kazimierczak, Clara Tenkerian, Andreas Ioannis Papadakis, S Wang, Sidong Huang, Antonis E. Koromilas · 2015 · Cell Death and Disease
- 1,3,5-Triazine as a Modular Scaffold for Covalent Inhibitors with Streamlined Target IdentificationRanjan Banerjee, Nicholas J. Pace, Douglas R. Brown, Eranthie Weerapana · 2013 · Journal of the American Chemical Society
- Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cellsJeffrey J. Rodvold, Kevin Chiu, Nobuhiko Hiramatsu, Julia K. Nussbacher, Valentina Galimberti, Navin R. Mahadevan, Karl Willert, Jonathan H. Lin, Maurizio Zanetti · 2017 · Science Signaling
- Structure and function of longin SNAREsFrédéric Daste, Thierry Galli, David C. Tareste · 2015 · Journal of Cell Science
- Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell ViabilityPaul E. Harrington, Kaustav Biswas, David J. Malwitz et al. · 2014 · ACS Medicinal Chemistry Letters
- SelK is a novel ER stress-regulated protein and protects HepG2 cells from ER stress agent-induced apoptosisShaoqing Du, Jun Zhou, Yi Jia, Kaixun Huang · 2010 · Archives of Biochemistry and Biophysics
- GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human diseaseLaurence A. Booth, Jane L. Roberts, Devin R. Cash, Seyedmehrad Tavallai, Sophonie Jean, Abigail Fidanza, Tanya Cruz‐Luna, Paul Siembiba, Kelly A. Cycon, Cynthia Nau Cornelissen et al. · 2014 · Journal of Cellular Physiology
- Cancer Microenvironment and Endoplasmic Reticulum Stress ResponseClaudia Giampietri, Simonetta Petrungaro, Silvia Conti, Antonio Facchiano, Antonio Filippini, Elio Ziparo A · 2015 · Mediators of Inflammation
- Amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genesLuigi Montibeller, Jacqueline de Belleroche · 2018 · Cell Stress and Chaperones
- A Striking Quality Control Subcompartment inSaccharomyces cerevisiae: The Endoplasmic Reticulum-associated CompartmentGregory Huyer, Gaby L. Longsworth, Deborah L. Mason, Monica P. Mallampalli, J. Michael McCaffery, Robin Wright, Susan Michaelis · 2003 · Molecular Biology of the Cell
- Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s InteractionJunli Liu, Dorina Ibi, Koji Taniguchi, Jaemin Lee, Hilde Herrema, Bedia Akosman, Patrick Mucka, Mario Andrés Salazar Hernández, Muhemmet Fatih Uyar, Sang Won Park et al. · 2016 · Cell
- mRNA Translation and Energy Metabolism in Cancer: The Role of the MAPK and mTORC1 PathwaysIvan Topisirović, Nahum Sonenberg · 2011 · Cold Spring Harbor Symposia on Quantitative Biology
- Increased mitochondrial respiration promotes survival from endoplasmic reticulum stressJeffrey Knupp, Peter Arvan, Amy Chang · 2018 · Cell Death and Differentiation
- Treatment of murine collagen‐induced arthritis by the stress protein BiP via interleukin‐4–producing regulatory T cells: A novel function for an ancient proteinRebecca J. Brownlie, Linda K. Myers, Paul H. Wooley · 2006 · Arthritis & Rheumatism
- Activation of IRE1α-XBP1 pathway induces cell proliferation and invasion in colorectal carcinomaChun Jin, Zhao Yang Jin, Nian-zhao Chen · 2015 · Biochemical and Biophysical Research Communications
- Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formationMitsuko Hayashi, Naonobu Fujita, Takeshi Noda, Akihito Yamaguchi, Tamotsu Yoshimori, Akitsugu Yamamoto · 2010 · Autophagy
- Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive LigandsHannah C. Feldman, Michael Tong, Likun Wang, Rosa Meza-Acevedo, Theodore A. Gobillot, Ivan Lebedev, Micah J. Gliedt, Sanjay B. Hari, Arinjay Mitra, Bradley J. Backes et al. · 2016 · ACS Chemical Biology
- Tumor-derived chaperone-rich cell lysates are effective therapeutic vaccines against a variety of cancersMichael W. Graner, Yi Zeng, Hanping Feng · 2003 · Cancer Immunology Immunotherapy
- Physiological IRE-1-XBP-1 and PEK-1 Signaling in Caenorhabditis elegans Larval Development and ImmunityClaire E. Richardson, Stephanie Kinkel, Dennis H. Kim · 2011 · PLoS Genetics
- ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosisHoukai Li, Qingshu Meng, Fei Xiao, Shanghai Chen, Ying Du, Junjie Yu, Chunxia Wang, Feifan Guo · 2011 · Biochemical Journal
- Inhibition of RNase L and RNA-dependent Protein Kinase (PKR) by Sunitinib Impairs Antiviral Innate ImmunityBabal Kant Jha, Irina V. Polyakova, Patricia Kessler, Beihua Dong, Benjamin K. Dickerman, Ganes C. Sen, Robert H. Silverman · 2011 · Journal of Biological Chemistry
- Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequencesAngela M. Arensdorf, Danilo R. Diedrichs, D. Thomas Rutkowski · 2013 · Frontiers in Genetics
- X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic α-Cell FunctionMasaru Akiyama, Chong Wee Liew, Shusheng Lu, Jiang Yong Hu, Rachael Martinez, Ben Hambro, Robert T. Kennedy, Rohit Kulkarni · 2013 · Diabetes
- Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stressM. Bouchecareilh, Arisa Higa, S. Fribourg, M. Moenner, É. Chevet · 2011 · The FASEB Journal
- Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodelingKazunori Hamamura, Hiroki Yokota · 2007 · FEBS Letters
- BRD7 Regulates XBP1s’ Activity and Glucose Homeostasis through Its Interaction with the Regulatory Subunits of PI3KSang Won Park, Hilde Herrema, Mario Salazar, Işın Çakır, Serkan Cabi, Fatma Basibuyuk Sahin, Yu‐Hsin Chiu, Lewis C. Cantley, Umut Özcan · 2014 · Cell Metabolism
- RNase domains determine the functional difference between IRE1α and IRE1βYusuke Imagawa, Akira Hosoda, Shin-ichi Sasaka, Akio Tsuru, Kenji Kohno · 2008 · FEBS Letters
- Brefeldin A as a regulator of grp78 gene expression in mammalian cells.Eloise Liu, J.-H. James Ou, Amy Shiu Lee · 1992 · Journal of Biological Chemistry
- Transcription Factor CREB3L1 Regulates Vasopressin Gene Expression in the Rat HypothalamusMingkwan Greenwood, Loredana Bordieri, Michael Paul Greenwood · 2014 · Journal of Neuroscience
- The Endoplasmic Reticulum Stress Transducer OASIS Is involved in the Terminal Differentiation of Goblet Cells in the Large IntestineRie Asada, Atsushi Saito, Noritaka Kawasaki, Soshi Kanemoto, Hideo Iwamoto, Mami Oki, Hidetaka Miyagi, Soutarou Izumi, Kazunori Imaizumi · 2012 · Journal of Biological Chemistry
- Control of the Unfolded Protein Response in Health and DiseaseDimitrios Doultsinos, Tony Avril, Stéphanie Lhomond, Nicolas Dejeans, Philippe Guédat, Éric Chevet · 2017 · SLAS DISCOVERY
- Characteristics of eukaryotic initiation factor 2 and its subunits.MICHELE A. LLOYD, James C. Osborne, B Safer · 1980 · Journal of Biological Chemistry
- Hac1: A novel yeast bZIP protein binding to the CRE motif is a multicopy suppressor for cdcW mutant of Schizosaccharomyces pombeHiroshi Nojima, Sun‐Hee Leem, Hiroyuki Araki · 1994 · Nucleic Acids Research
- Kaempferol Protects Ischemia/Reperfusion-Induced Cardiac Damage Through the Regulation of Endoplasmic Reticulum StressDo‐Sung Kim, Ki-Chan Ha, Dae‐Young Kwon, Myung‐Sunny Kim, Hyung‐Ryong Kim, Soo‐Wan Chae, Han–Jung Chae · 2008 · Immunopharmacology and Immunotoxicology
- In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stressMegan C Kopp, Piotr R. Nowak, Natacha Larburu, Christopher J Adams, Maruf M. U. Ali · 2018 · eLife
- Portability and fidelity of RNA-repair systemsBeate Schwer, Rana M. Sawaya, C. Kiong Ho · 2004 · Proceedings of the National Academy of Sciences
- Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditionsYi‐Jiun Chen, Bertrand Chin‐Ming Tan, Ya-Yun Cheng · 2009 · Nucleic Acids Research
- Activating Transcription Factor 4 Promotes Esophageal Squamous Cell Carcinoma Invasion and Metastasis in Mice and Is Associated with Poor Prognosis in Human PatientsHongwu Zhu, Xiong Chen, Bin Chen, Bei Chen, Wei-Bing Song, Dayong Sun, YA-GANG ZHAO · 2014 · PLoS ONE
- Physiological ER Stress Mediates the Differentiation of FibroblastsShinsuke Matsuzaki, Toru Hiratsuka, Manabu Taniguchi, Kenta Shingaki, Tateki Kubo, Koichiro Kiya, 藤原敏宏, Shigeyuki Kanazawa, Ryutaro Kanematsu, Tameyasu Maeda et al. · 2015 · PLoS ONE
- A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila developmentMichio Sone, Xiaomei Zeng, Joseph Larese · 2012 · Cell Stress and Chaperones
- Mesencephalic Astrocyte–Derived Neurotrophic Factor as a Urine Biomarker for Endoplasmic Reticulum Stress–Related Kidney DiseasesYeawon Kim, Heedoo Lee, Scott R. Manson, Maria Lindahl, Bradley S. Evans, Jeffrey H. Miner, Fumihiko Urano, Ying Maggie Chen · 2016 · Journal of the American Society of Nephrology
- Altered Metabolism of Growth Hormone Receptor Mutant Mice: A Combined NMR Metabonomics and Microarray StudyHorst Joachim Schirra, Cameron G. Anderson, W.J. Wilson, Linda M. Kerr, David J. Craik, Michael J. Waters, Agnieszka M Lichanska · 2008 · PLoS ONE
- Targeted Disruption of CRE-Binding Factor TREB5 Gene Leads to Cellular Necrosis in Cardiac Myocytes at the Embryonic StageTamotsu Masaki, Mitsuaki Yoshida, Shigeru Noguchi · 1999 · Biochemical and Biophysical Research Communications
- Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouseXiaochu Zhang, Eva Szabo, Marek Michalak, Michał Opas · 2007 · International Journal of Developmental Neuroscience
- A Knowledge Generation Model via the HypernetworkJian-Guo Liu, Guang-Yong Yang, Zhao-Long Hu · 2014 · PLoS ONE
- Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non–Small Cell Lung Cancer Cell Lines and Tumor ModelsDavid Y. A. Dadey, Vaishali Kapoor, Kelly Hoye, Arpine Khudanyan, Andrea R. Collins, Dinesh Kumar Thotala, Dennis E. Hallahan · 2016 · Clinical Cancer Research
- Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulationLijia Bu, Hanqing Yu, Lulu Fan et al. · 2017 · World Journal of Gastroenterology
- Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xLYanfang Wu, Xia Li, Junying Jia, Yanpeng Zhang, Jing Li, Zhengmao Zhu, Huaqing Wang, Jie Tang, Junjie Hu · 2018 · Proceedings of the National Academy of Sciences
- Endoplasmic reticulum stress in periimplantation embryosMarek Michalak, Myung Chan Gye · 2015 · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine
- Endoplasmic Reticulum Stress Signaling in Mammalian Oocytes and Embryos: Life in BalanceKeith E. Latham · 2015 · International review of cytology
- Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathwaySatoshi Kanda, Kota Yanagitani, Yukiko Yokota, Yuta Esaki, Kenji Kohno · 2016 · Proceedings of the National Academy of Sciences
- Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growthBojan Bujisic, Aude De Gassart, Rémy Tallant, Olivier Demaria, Léa Zaffalon, Sonia Tassadit Chelbi, Michel F. Gilliet, Francesco Bertoni, Fabio Martinon · 2017 · Blood
- Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failureShun‐Guang Wei, Yang Yu, Robert M. Weiss, Robert B. Felder · 2016 · American Journal of Physiology-Heart and Circulatory Physiology
- IRE1–RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liverDong Liu, Xing Liu, Ti Zhou, William W. Yao, Jun Zhao, Zhigang Zheng, Wei Jiang, Fengsong Wang, Felix O. Aikhionbare, Donald L. Hill et al. · 2015 · Journal of Molecular Cell Biology
- 4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Stress, Trypsin Activation, and Acinar Cell Apoptosis While Increasing Secretion in Rat Pancreatic AciniAntje Malo, Burkhard Krüger, Burkhard Göke · 2012 · Pancreas
- Regulation of the unfolded protein response by microRNAsSylwia Bartoszewska, Kinga Kochan, Piotr Madanecki, Arkadiusz Piotrowski, J. Renata Ochocka, James F. Collawn, Rafał Bartoszewski · 2013 · Cellular & Molecular Biology Letters
- Increased Amino Acid Uptake Supports Autophagy-Deficient Cell Survival upon Glutamine DeprivationNan Zhang, Xin Ping Yang, Fengjie Yuan, Luyao Zhang, Yanan Wang, Lina Wang, Zebin Mao, Jianyuan Luo, Hongquan Zhang, Wei‐Guo Zhu et al. · 2018 · Cell Reports
- Endoplasmic Reticulum Stress Induces Epithelial-Mesenchymal Transition through Autophagy via Activation of c-Src KinaseSoo Young Moon, Hyo Sang Kim, Kyeong Woo Nho · 2014 · Nephron Experimental Nephrology
- A Conserved Structural Determinant Located at the Interdomain Region of Mammalian Inositol-requiring Enzyme 1αZhen Hua Xue, Yin He, Kaixiong Ye · 2011 · Journal of Biological Chemistry
- Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fishTokiro Ishikawa, Makoto Kashima, Atsushi J. Nagano · 2017 · eLife
- A hybrid protein kinase‐RNase in an interferon‐induced pathway?Peer Bork B, Chris Sander · 1993 · FEBS Letters
- Thermotolerance induced at a mild temperature of 40°C protects cells against heat shock‐induced apoptosisAhmed Bettaieb, Diana A. Averill‐Bates · 2005 · Journal of Cellular Physiology
- Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesisChristopher E. Lowe, Rowena J. Dennis, U Obi, Stephen O’Rahilly, Justin J. Rochford · 2011 · International Journal of Obesity
- The UPR reduces glucose metabolism via IRE1 signalingJudith M. van der Harg, Jessica C van Heest, Fabian N. Bangel · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- UPR Signal Activation by Luminal Sensor DomainsMarta Carrara, Filippo Prischi, Maruf M. U. Ali · 2013 · International Journal of Molecular Sciences
- Tunicamycin inhibits glycosylation of precursor polyprotein encoded by env gene of Rauscher murine leukemia virusAlan M. Schultz, Stephen I. Oroszlan · 1979 · Biochemical and Biophysical Research Communications
- Regulation of the unfolded protein response by noncoding RNAMari McMahon, Afshin Samali, Éric Chevet · 2017 · American Journal of Physiology-Cell Physiology
- Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stressRoberto Bravo, Jose Miguel Vicencio, Valentina Parra, Rodrigo Troncoso, Juan Pablo Muñoz, Michael Bui, Clara Quiroga, Andrea E. Rodriguez, Hugo Verdejo, Jorge Ferreira et al. · 2011 · Journal of Cell Science
- Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion InjuryEmma Folch‐Puy, Arnau Panisello Rosello, Joan Oliva, Alexandre López, Carlos Castro Benítez, René A. Adam, Joan Roselló‐Catafau · 2016 · International Journal of Molecular Sciences
- Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathwayYu‐Jia Chang, Wei-Yu Chen, Chien‐Yu Huang, Hui-Hsiung Liu, Po‐Li Wei · 2014 · Tumor Biology
- Riluzole induces apoptotic cell death in human prostate cancer cells via endoplasmic reticulum stress.Kanako Akamatsu, Masa-Aki Shibata, Yuko Ito · 2009 · PubMed
- Safety and patient response as indicated by biomarker changes to binding immunoglobulin protein in the phase I/IIA RAGULA clinical trial in rheumatoid arthritisBruce W Kirkham, Khaldoun Chaabo, Christopher L. Hall et al. · 2016 · Lara D. Veeken
- The role of the endoplasmic reticulum stress in stemness, pluripotency and developmentKateřina Vašíčková, Lukáš Moráň, Stanislava Paďourová, Stanislav Stejskal, Lenka Tesařová, Pavel Šimara, Aleš Hampl, Irena Koutná, Petr Vaňhara · 2016 · European Journal of Cell Biology
- Angiogenin Mediates Cell-Autonomous Translational Control under Endoplasmic Reticulum Stress and Attenuates Kidney InjuryIadh Mami, Nicolas Bouvier, Khalil El Karoui, Morgan Gallazzini, Marion Rabant, Pierre Laurent‐Puig, Shuping Li, Pierre‐Louis Tharaux, Philippe H. Beaune, Éric Thervet et al. · 2015 · Journal of the American Society of Nephrology
- Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human OsteosarcomaJielai Yang, Dongdong Cheng, Shumin Zhou, Bin Zhu, Tu Hu, Qingcheng Yang · 2015 · International Journal of Molecular Sciences
- Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase functionIrene Cheng Jie Lee, Xue Yan Ho, Simi Elizabeth George, Catherine Wenhui Goh, Jeyapriya Rajameenakshi Sundaram, Karen Ka Lam Pang, Weiwei Luo, Permeen Yusoff, Newman Siu Kwan Sze, Shirish Shenolikar · 2017 · Cell Death and Differentiation
- Endoplasmic Reticulum Stress Inhibition Enhances Liver Tolerance to Ischemia/ReperfusionCarmen Peralta, Catherine Brenner · 2011 · Current Medicinal Chemistry
- Syringin attenuates insulin resistance via adiponectin-mediated suppression of low-grade chronic inflammation and ER stress in high-fat diet-fed miceBobae Kim, Min-Seok Kim, Chang‐Kee Hyun · 2017 · Biochemical and Biophysical Research Communications
- Heat Shock 70-kDa Protein 5 (Hspa5) Is Essential for Pronephros Formation by Mediating Retinoic Acid SignalingWeili Shi, Gang Xu, Chengdong Wang, Steven M. Sperber, Yonglong Chen, Qin Zhou, Yi Deng, Hui Zhao · 2014 · Journal of Biological Chemistry
- 折り畳まれていない蛋白質応答トランスデューサIRE1αの調節因子としてのインタラクトームスクリーニングER内腔シャペロンH sp47を同定する【Powered by NICT】Sepulveda Denisse, Rojas-Rivera Diego, A Rodriguez Diego, Groenendyk Jody, Andrés Kohler, Cynthia Lebeaupin, Ito Shinya, Hery Urra, Amado Carreras‐Sureda, Hazari Younis et al. · 2018 · Molecular Cell
- Endoplasmic reticulum stress-mediated upregulation of miR-29a enhances sensitivity to neuronal apoptosisNolan, Katie, Walter, Franziska, Tuffy, Liam P., Poeschel, Simone, Gallagher, Ross, Haunsberger, Stefan, Bray, Isabella, Stallings, Raymond L., Concannon, Caoimhín G., Prehn, Jochen H. M. · 2016 · European Journal of Neuroscience
- Transmissible endoplasmic reticulum stress from myocardiocytes to macrophages is pivotal for the pathogenesis of CVB3-induced viral myocarditisHui Zhang, Y. Yue, Tianle Sun, Xue-Jie Wu, S. Xiong · 2017 · Scientific Reports
- DNA vaccination with gp96-peptide fusion proteins induces protection against an intracellular bacterial pathogenUlrike K Rapp · 2004 · International Immunology
- New insights into the unfolded protein response in stem cellsYanzhou Yang, Hoi‐Hung Cheung, Jiajie Tu, Kai-Kei Miu, Wai‐Yee Chan · 2016 · Oncotarget
- Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein ResponseDadi Jiang, Connor M. Lynch, Bruno C. Medeiros, Michaela Liedtke, Rakesh Bam, Arvin B. Tam, Zhifen Yang, Muthuraman Alagappan, Parveen Abidi, Quynh‐Thu Le et al. · 2016 · Scientific Reports
- Bcr-Abl reduces endoplasmic reticulum releasable calcium levels by a Bcl-2–independent mechanism and inhibits calcium-dependent apoptotic signalingKatarzyna Piwocka, Susanne Vejda, Thomas G. Cotter · 2006 · Blood
- SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 ActivationTatsuro Kawamura, Etsu Tashiro, Kohta Yamamoto · 2008 · The Journal of Antibiotics
- Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeastRan Tao, Hua Chen, Chan Gao · 2011 · Cell Research
- mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under StressClara Tenkerian, Jothilatha Krishnamoorthy, Zineb Mounir, Urszula Kazimierczak, Arkady Khoutorsky, Kirk A. Staschke, Arnold S. Kristof, Shuo Wang, Maria Hatzoglou, Antonis E. Koromilas · 2015 · Molecular Cancer Research
- Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesisYiguang Lin, Jieli Shen, E Yoo, R Liu, H-y Yen, A Mehta, A Rajaei, W Yang, Paulette Y. Mhawech-Fauceglia, Francesco John DeMayo et al. · 2015 · Oncogene
- ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expressionChun-Xia Wang, Houkai Li, Qingshun Meng, Ying Du, Fei Xiao, Qian Zhang, J. Yu, Kai Li, Shang-Hai Chen, Zhiying Huang et al. · 2013 · Journal of Cellular and Molecular Medicine
- OASIS modulates hypoxia pathway activity to regulate bone angiogenesisMin Cui, Soshi Kanemoto, Xiang Cui, Masayuki Kaneko, Rie Asada, Koji Matsuhisa, Keiji Tanimoto, Yuki Yoshimoto, Chisa Shukunami, Kazunori Imaizumi · 2015 · Scientific Reports
- Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couple ER stress to mitochondrial apoptosisPatricia Gomez‐Bougie, Maxime Halliez, Philippe Moreau, Catherine Pellat‐Deceunynck, Martine Amiot · 2016 · Cancer Letters
- Inositol-requiring protein 1 – X-box-binding protein 1 pathway promotes epithelial–mesenchymal transition via mediating snail expression in pulmonary fibrosisXiaoting Mo, Wencheng Zhou, Wenhui Cui · 2015 · The International Journal of Biochemistry & Cell Biology
- Myeloma cell line–derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myelomaJianfei Qian, Sungyoul Hong, Siqing Wang, Liang Zhang, Luhong Sun, Michael L. Wang, Jing Yang, Larry W. Kwak, Jian Hou, Qing Yi · 2009 · Blood
- Assisting Oxidative Protein Folding: How Do Protein Disulphide-Isomerases Couple Conformational and Chemical Processes in Protein Folding?A. Katrine Wallis, Robert B. Freedman · 2011 · Topics in current chemistry
- The Unfolded Protein Response Contributes to Preimplantation Mouse Embryo Death in the DDK Syndrome1Lanping Hao, Rita Vassena, Guangming Wu · 2009 · Biology of Reproduction
- Physiological functions of endoplasmic reticulum stress transducer OASIS in central nervous systemAtsushi Saito · 2013 · Anatomical Science International
- Inflammation and ER stress downregulate BDH2 expression and dysregulate intracellular iron in macrophagesZughaier, Susu M., Stauffer, Brandon B., McCarty, Nael A. · 2014 · Journal of Immunology Research
- A transgenic zebrafish model for monitoring xbp1 splicing and endoplasmic reticulum stress in vivoJunling Li, Zhiliang Chen, Lian‐Yong Gao, A. Colorni, Michal Ucko, Shengyun Fang, Shaojun Du · 2015 · Mechanisms of Development
- Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modificationSusana M. Tomásio, Heather P. Harding, David Ron, Benedict C. S. Cross, Peter John Bond · 2013 · Molecular BioSystems
- Touché! STARD3 and STARD3NL tether the ER to endosomesLéa P. Wilhelm, Catherine Tomasetto, Fabien Alpy · 2016 · Biochemical Society Transactions
- Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stressSun Kwan Kwon, Moonsang Ahn, Hee‐Jung Song et al. · 2015 · Brain Research
- Heat stress activates ER stress signals which suppress the heat shock response, an effect occurring preferentially in the cortex in ratsYaohua Liu, Hiroaki Sakamoto, Masaaki Adachi, Shiguang Zhao, Wataru Ukai, Eri Hashimoto, Masato Hareyama, Tadao Ishida, Kohzoh Imai, Yasuhisa Shinomura · 2011 · Molecular Biology Reports
- Phase II Trial of Adjuvant Immunotherapy with Autologous Tumor-derived Gp96 Vaccination in Patients with Gastric CancerKecheng Zhang, Zheng Peng, Xiaohui Huang et al. · 2017 · Journal of Cancer
- Uric acid‐induced endoplasmic reticulum stress triggers phenotypic change in rat glomerular mesangial cellsShasha Li, Fei Zhao, Shaoli Cheng · 2013 · Nephrology
- Endoplasmic Reticulum Chaperones and Their Roles in the Immunogenicity of Cancer VaccinesMichael W. Graner, Kevin O. Lillehei, Emmanuel Katsanis · 2015 · Frontiers in Oncology
- Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein responseFiona E. Chalmers, Marcel van Lith, Bernadette Sweeney · 2017 · Wellcome Open Research
- Edaravone protects against glutamate-induced PERK/EIF2α/ATF4 integrated stress response and activation of caspase-12Jin Fan, Hao Long, Yiming Li · 2013 · Brain Research
- Stochastic Heterogeneous Interaction Promotes Cooperation in Spatial Prisoner's Dilemma GamePing Zhu, Guiyi Wei · 2014 · PLoS ONE
- Genetic targeting of the active transcription factor XBP1s to dendritic cells potentiates vaccine-induced prophylactic and therapeutic antitumor immunity.Shenghe Tian, Zu-Qiang Liu, C. Donahue, L. Falo, Z. You · 2012 · Molecular Therapy
- Effect of hypoxia on the expression of genes encoding insulin-like growth factors and some related proteins in U87 glioma cells without IRE1 functionDmytro O. Minchenko, Anastasia P. Kharkova, Oleh V. Halkin, Leonid L. Karbovskyi, О. H. Minchenko · 2016 · Endocrine Regulations
- Silencing of both ATF4 and PERK inhibits cell cycle progression and promotes the apoptosis of differentiating chondrocytesZhimeng Wu, Meiling Li, Wei Zheng, Qin Hu, Zhi Cheng, Fengjin Guo · 2017 · International Journal of Molecular Medicine
- Characterization of IRE 1 ribonuclease‐mediated mRNA decay in plants using transient expression analyses in rice protoplastsShimpei Hayashi, Yuhya Wakasa, Kenjirou Ozawa · 2016 · New Phytologist
- Regulation of hepatic lipogenesis.Korchak Hm · 1998 · PubMed
- Activating Transcription Factor 6α Is Required for the Vasopressin Neuron System to Maintain Water Balance Under Dehydration in Male MiceYoshinori Azuma, Daisuke Hagiwara, Wenjun Lu et al. · 2014 · Endocrinology
- SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 ActivationTatsuro Kawamura, Etsu Tashiro, Kazutoshi Shindo · 2008 · The Journal of Antibiotics
- mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell linesPatricia Freis, Julien Bollard, Justine Lebeau, Patrick Massoma, Joëlle Fauvre, Cécile Vercherat, Thomas Walter, Serge N. Manié, Colette Roche, Jean‐Yves Scoazec et al. · 2017 · Oncotarget
- Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1Juan Rong, Ian Pass, Paul W. Diaz, Tram A. Ngo, Michelle Sauer, Gavin Magnuson, Fu‐Yue Zeng, Christian A. Hassig, Michael R. Jackson, Nicholas D. P. Cosford et al. · 2015 · SLAS DISCOVERY
- A Covalent Cysteine‐Targeting Kinase Inhibitor of Ire1 Permits Allosteric Control of Endoribonuclease ActivityDaniel Dirck Waller, Gregor Jansen, Makan Golizeh, Chloe Martel‐Lorion, Kurt Dejgaard, Tze Chieh Shiao, John Mancuso, Youla S. Tsantrizos, René Roy, Michaël Sébag et al. · 2016 · ChemBioChem
- Cooling-Induced ER Stress is Good for Your BrainBertrand Mollereau · 2015 · EBioMedicine
- PERK/eIF2α contributes to changes of insulin signaling in HepG2 cell induced by intermittent hypoxiaHuahua Yi, Chenjuan Gu, Min Li, Zhiguo Zhang, Qing Yun Li, Jing Feng, Jun Zhou, Juan Du · 2017 · Life Sciences
- Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein responseFiona E. Chalmers, Bernadette Sweeney, Katharine Cain · 2017 · Wellcome Open Research
- Erratum To: Mfn2 modulates the UPR and mitochondrial function via repression of PERKJuan Pablo Muñoz, Saška Ivanova, Jana Sánchez et al. · 2014 · The EMBO Journal