Non‐pharmacological treatment reducing not only behavioral symptoms, but also psychotic symptoms of older adults with dementia: A prospective cohort study in T aiwan
Abstract
Aim: The clinical effectiveness of non‐pharmacological interventions on behavioral and psychological symptoms of dementia ( BPSD ) among older C hinese with dementia remains unclear, and the evidence supporting the benefits of a non‐pharmacological approach on psychotic symptoms is scarce. Methods: A prospective cohort study including 104 older men with dementia living in two veterans homes in T aiwan was carried out in 2011. An organized program of music therapy, orientation training, art‐cognitive activities and physical activities was carried out for the intervention group. All participants were evaluated for neuropsychiatric inventory (NPI), defined daily dose of psychotropic drug use, B arthel I ndex, I nstrumental A ctivities of D aily L iving, M ini‐ M ental S tate E xamination, G eriatric D epression S cale, T inetti balance score and T inetti gait score. Results: Overall, 104 residents were enrolled and 92 of them completed the study. The intervention group had a more significant reduction than the reference group in the overall NPI score (−2.36, P = 0.046), and in the subcategories of delusion (−0.9, P = 0.018), hallucination (−0.82, P = 0.004) and agitation (−0.91, P = 0.038). Multivariate analysis showed that the non‐pharmacological intervention was associated with a favorable outcome in overall NPI score ( OR 4.113, P = 0.013) and in the subcategories of hallucination ( OR 14.309, P = 0.049) and agitation ( OR 6.604, P = 0.037). Meanwhile, a higher baseline NPI score was also associated with a favorable outcome in overall NPI score, and in the subcategories of delusion, hallucination and agitation. Conclusion: Non‐pharmacological interventions have a positive effect on behavioral and psychological symptoms of dementia, not only in outward symptoms like agitation, but also intrinsic psychotic symptoms like hallucination and delusion, and agitation in older Chinese men with dementia. Geriatr Gerontol Int 2013; 14: 440–446.
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One study showed that an organized nonpharmacological intervention program was effective in managing both outward and intrinsic symptoms, including hallucination and delusion.
“one study showed that an organized nonpharmacological intervention program was effective in managing both outward and intrinsic symptoms, including hallucination and delusion [23].”
From Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review (2015) · cites this paper as [23]
Nonpharmacological alternatives, including music therapy, aromatherapy, art therapy, behavioral therapy, reality orientation, tailored activities, and physical exercises, have shown promising results for the management of BPSD.
“Nonpharmacological alternatives, including music therapy, aromatherapy, art therapy, behavioral therapy, reality orientation, tailored activities, and physical exercises, have shown promising results for the management of BPSD [21–23].”
From Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review (2015) · cites this paper as [23]
The intervention group had more significant reduction than the reference group in the NPI score (p = 0.046), including delusion (p = 0.018), hallucination (p = 0.004), and agitation (p = 0.038).
“The intervention group had more significant reduction than the reference group in the NPI score (p = 0.046), including delusion (p = 0.018), hallucination (p = 0.004), and agitation (p = 0.038) [23].”
From Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review (2015) · cites this paper as [23]
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- Authors
- Chen, R., Liu, C., Lin, M., Peng, L., Chen, L., Liu, L., & Chen, L.
- Affiliations
- Taipei City Hospital (TW)
- Taipei Veterans General Hospital (TW)
- Corresponding author
- Chen, Liang‐Kung
- Venue
- Geriatrics & Gerontology International
- Publisher
- Wiley
- Published
- 2013-08
- Volume
- 14
- Issue
- 2
- Pages
- 440-446
- ISSN
- 1444-1586 (ISSN-L)
- 1447-0594
- OpenAlex
- W2134439718
- Cited by
- 62
- References
- 26
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 5 · 2020: 2 · 2019: 6 · 2018: 8 · 2017: 10 · 2016: 8 · 2015: 5 · 2014: 1 · 2013: 1
- FWCI
- 3.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Geriatrics and gerontology international/Geriatrics & gerontology international (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- dementia, non-pharmacological treatment, behavioral and psychological symptoms of dementia, psychotic symptoms, hallucinations, delusions, agitation, music therapy, orientation training, physical activity, veterans' homes, psychotropic drug use
- MeSH terms
- Aged, 80 and over, Behavioral Symptoms, Dementia, Humans, Male, Prospective Studies, Psychotic Disorders, Taiwan, Cohort Studies, Asian People
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