The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Th9 cells: differentiation and disease
Open accessAbstract
Summary: CD 4+ T‐helper cells regulate immunity and inflammation through the acquisition of potential to secrete specific cytokines. The acquisition of cytokine‐secreting potential, in a process termed T‐helper cell differentiation, is a response to multiple environmental signals including the cytokine milieu. The most recently defined subset of T‐helper cells are termed Th9 and are identified by the potent production of interleukin‐9 (IL‐9). Given the pleiotropic functions of IL‐9, Th9 cells might be involved in pathogen immunity and immune‐mediated disease. In this review, I focus on recent developments in understanding the signals that promote Th9 differentiation, the transcription factors that regulate IL‐9 expression, and finally the potential roles for Th9 cells in immunity in vivo.
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Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
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Stat6-Independent GATA-3 Autoactivation Directs IL-4-Independent Th2 Development and Commitment
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Saigusa, R., Winkels, H., & Ley, K. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0352-5 · Cited by 721
Biology and regulation of IL-2: from molecular mechanisms to human therapy
Spolski, R., Li, P., & Leonard, W. J. (2018) · Nature Reviews Immunology · doi:10.1038/s41577-018-0046-y · Cited by 637
Basha, S., Surendran, N., & Pichichero, M. (2014) · Expert Review of Clinical Immunology · doi:10.1586/1744666x.2014.942288 · Cited by 513
Gerlach, K., Hwang, Y., Nikolaev, A., Atreya, R., Dornhoff, H., Steiner, S., Lehr, H.-A., Wirtz, S., Vieth, M., Waisman, A., et al. (2014) · Nature Immunology · doi:10.1038/ni.2920 · Cited by 407
The development and in vivo function of T helper 9 cells
Kaplan, M. H., Hufford, M. M., & Olson, M. R. (2015) · Nature Reviews Immunology · doi:10.1038/nri3824 · Cited by 384
Self-citation
Metadata
- Authors
- Kaplan, M. H.
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2013-02-13
- Volume
- 252
- Issue
- 1
- Pages
- 104-115
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- OpenAlex
- W2066740231
- Cited by
- 320
- References
- 84
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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