The DOI matches its Crossref record; 218 of the 218 references it cites were found in a registry or an index.
Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL–RANK signaling system
Abstract
Summary: Osteoclasts are primary cells for physiological and pathological bone resorption, and receptor activator of nuclear factor‐κB ligand (RANKL) is critically involved in the differentiation, activation, and survival of these cells. Recently, therapeutics for pathological bone destruction targeting RANKL pathways has attracted a great deal of attention. Herein, we review the recent advances in the research on osteoclast biology and discuss the advantages and disadvantages of anti‐RANKL therapies.
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Cites
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“Osteoclasts are specifically differentiated for bone resorption (8, 11).”
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Self-citation
Cited by
Hikita, A., Yana, I., Wakeyama, H., Nakamura, M., Kadono, Y., Oshima, Y., Nakamura, K., Seiki, M., & Tanaka, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m606656200 · Cited by 236
Self-citationPLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2
Mao, D., Epple, H., Uthgenannt, B., Novack, D. V., & Faccio, R. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28775 · Cited by 214
Osteocytic signalling pathways as therapeutic targets for bone fragility
Plotkin, L. I., & Bellido, T. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.71 · Cited by 206
Impaired Micro-RNA Pathways Diminish Osteoclast Differentiation and Function
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Vieira Ribeiro, F., de Mendonça, A. C., Santos, V. R., Bastos, M. F., Figueiredo, L. C., & Duarte, P. M. (2011) · Journal of Periodontology · doi:10.1902/jop.2011.100643 · Cited by 121
Metadata
- Authors
- Tanaka, S., Nakamura, K., Takahasi, N., & Suda, T.
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2005-11-22
- Volume
- 208
- Issue
- 1
- Pages
- 30-49
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- OpenAlex
- W2052712126
- Cited by
- 320
- References
- 218
- FWCI
- 0.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tanaka, S., Nakamura, K., Takahasi, N., & Suda, T. (2005). Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL–RANK signaling system. Immunological Reviews. https://doi.org/10.1111/j.0105-2896.2005.00327.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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