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ON THE PREVALENCE OF ADRENOCORTICAL ADENOMAS IN AN AUTOPSY MATERIAL IN RELATION TO HYPERTENSION AND DIABETES
Abstract
Abstract A prospective study was performed on an autopsy material consisting of 739 consecutive cases over 20 years of age (391 females, 348 males) during a period of six months. The material included about 70% of the deaths in the city of Malmö (approximately 250,000 inhabitants). The adrenals were specially observed at autopsy for adenomas and hospital records were searched for hypertension and diabetes mellitus. In the total material the frequency of adrenocortical adenomas was 8.7%, which was considerably higher than previously reported figures. In patients with essential hypertension the adenoma frequency was 12.4% as against 7.9% in normotensives. This difference was not statistically significant. The adenoma frequency in men with secondary hypertension was remarkably high but the significance is not clear. In patients with hypertension the frequency of diabetes was 17.6% as compared to 9.0% in normotensives. This difference was statistically probably significant. In patients with diabetes the frequency of adrenocortical adenomas was 16.5%, in non‐diabetics 7.7%. The difference was probably significant.
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“In the autopsy series with large patient numbers (series with greater than 1000 patients) (9-16), the reported prevalence of AI ranges from 1.05% (9) to 8.7% (10) (Table 1 (9-31)).”
From Adrenal incidentaloma (2020) · cites this paper as [10]
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Prager, G., Scheuba, C., Passler, C., Heinz‐Peer, G., Vierhapper, H., & Niederle, B. (1999) · European surgery. Supplement/European surgery · doi:10.1007/bf02619995 · Cited by 4
Gross, M. D., KOROBKIN, M. T., Hussain, H. K., Cho, K. J., & Chuong, B. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00105-2 · Cited by 3
Management of adrenal mass: What urologist should know
Suárez, M. H., Junquera, J. M. A., Boix, P., Dieguez, M., Delgado, E., García, J. M. A., & García, R. A. (2010) · Actas Urológicas Españolas (English Edition) · doi:10.1016/s2173-5786(10)70145-1 · Cited by 3
Abnormalities in Incidentally Removed Adrenal Glands
Buurman, H., & Saeger, W. (2006) · Endocrine Pathology · doi:10.1385/ep:17:3:277 · Cited by 3
Metadata
- Authors
- Hedeland, H., Östberg, G., & Hökfelt, B.
- Affiliations
- Lund University (SE)
- Venue
- Acta Medica Scandinavica
- Publisher
- Wiley
- Published
- 1968-01-12
- Volume
- 184
- Issue
- 1-6
- Pages
- 211-214
- ISSN
- 0001-6101 (ISSN-L)
- OpenAlex
- W2067873837
- Cited by
- 287
- References
- 10
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 5 · 2022: 3 · 2021: 4 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 2 · 2015: 9 · 2014: 6 · 2013: 4 · 2012: 6
- FWCI
- 4.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Medica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- adrenal adenoma, adrenal incidentaloma, prevalence, essential hypertension, secondary hypertension, diabetes mellitus, autopsy findings, adrenal gland
- MeSH terms
- Adenoma, Adrenal Gland Neoplasms, Adult, Aged, Diabetes Mellitus, Female, Humans, Hyperaldosteronism, Hypertension, Male, Middle Aged, Prospective Studies
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