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Cited by 161Adrenal and Paraganglionic TumorsHormonal Regulation and HypertensionAdrenal Hormones and Disorders

Small adenomas of the adrenal cortex in hypertension and diabetes

RUSSI, SIMON·1945·Archives of Internal Medicine
DOI 10.1001/archinte.1945.00210350030005
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Abstract

The principal observations generally reported concerning persons with tumors of the adrenal cortex consist of obesity, purple striae of the skin, acne, polycythemia,is, imbalanceplasma electrolytes, diabetes, hypertension genital dystrophy. These signs and symptoms have been observed in persons with adenohyperplasiasin those with carcinomas of the adrenal cortex, and the total picture is usually referred to as Cushing's disease or adrenogenital syndrome. In general, even the benign tumors which produce this clinical entity occupy a large portion of the adrenal gland. There are, in addition, as Kepler and Keating 1 pointed out, a large number of small cortical adenomasre encountereddentally in the course of routine autopsiespersons in whom there was no apparent clinical evidence of endocrine disease during life. The investigations presented here were undertaken in order to determine whether or not an examination of the clinical and pathologic data, in retrospect, would show the presence of certain endocrinologie disturbances not noted during the

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Crossref · 10.1001/archinte.1945.00210350030005

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  • In autopsy series with greater than 1000 patients, the reported prevalence of AI ranges from 1.05% to 8.7%.

    “In the autopsy series with large patient numbers (series with greater than 1000 patients) (9-16), the reported prevalence of AI ranges from 1.05% (9) to 8.7% (10) (Table 1 (9-31)).”

    From Adrenal incidentaloma (2020) · cites this paper as [11]

  • Previous imaging studies have reported that AIs are more common in females; however, this has not been observed in autopsy studies.

    “Previous imaging studies have reported that AIs are more common in females (66,71,73); however, this has not been observed in autopsy studies (11,85).”

    From Adrenal incidentaloma (2020) · cites this paper as [11]

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Authors
RUSSI, S.
Corresponding author
RUSSI, SIMON
Venue
Archives of Internal Medicine
Publisher
American Medical Association (AMA)
Published
1945-11-01
Volume
76
Issue
5
Pages
284
ISSN
0003-9926 (ISSN-L)
DOI
10.1001/archinte.1945.00210350030005
OpenAlex
W2074901715
Cited by
161
References
21
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 2 · 2012: 1
FWCI
7.49
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
adrenal adenoma, hypertension, diabetes mellitus, Cushing's disease, adrenogenital syndrome, endocrine disorders, autopsy findings, adrenal hyperplasia
MeSH terms
Adenoma, Adrenal Cortex, Adrenal Gland Neoplasms, Adrenal Glands, Blood Pressure, Diabetes Mellitus, Humans, Hypertension, Neoplasms

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