Adenomas of the adrenal cortex
Abstract
ADENOMAS of the adrenal cortex are reported in 1.45 to 33 per cent of all autopsies,1and they have been considered to be of significance in hypertension and diabetes mellitus.2This study represents an attempt to determine the incidence of adenomas of the adrenal cortex and to ascertain whether they occur more often in patients with hypertensive cardiovascular disease, cardiac enlargement, diabetes mellitus or gonadal changes. For this study, any roughly spherical nodule with a diameter greater than 3 mm. budding from an edge of the gland or into the medulla was considered to be an adenoma of the adrenal cortex. The tumors contained variable proportions of vacuolated and eosinophilic cells resembling those of the adrenal cortex. The histologic architecture, however, was distinctly different from that of normal adrenal cortex. None of the nodules showed evidence of malignant change. Detailed reports of cytologic and histologic characteristics have been
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In autopsy series with greater than 1000 patients, the reported prevalence of AI ranges from 1.05% to 8.7%.
“In the autopsy series with large patient numbers (series with greater than 1000 patients) (9-16), the reported prevalence of AI ranges from 1.05% (9) to 8.7% (10) (Table 1 (9-31)).”
From Adrenal incidentaloma (2020) · cites this paper as [12]
Cites
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The clinically inapparent adrenal mass: update in diagnosis and management
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Prevalence and natural history of adrenal incidentalomas
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“In the autopsy series with large patient numbers (series with greater than 1000 patients) (9-16), the reported prevalence of AI ranges from 1.”
BackgroundAdrenal incidentaloma: a new cause of the metabolic syndrome?
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- Authors
- COMMONS, R. R.
- Corresponding author
- COMMONS, ROBERT R.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1948-01-01
- Volume
- 81
- Issue
- 1
- Pages
- 37
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2299486385
- Cited by
- 121
- References
- 7
- Citations by year
- 2026: 1 · 2024: 1 · 2022: 1 · 2020: 2 · 2019: 1 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 1 · 2012: 3
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- adrenal adenoma, incidence, hypertension, diabetes mellitus, hypertensive heart disease, cardiomegaly, adrenal medulla
- MeSH terms
- Adenoma, Adrenal Cortex, Adrenal Gland Neoplasms, Adrenal Glands, Humans, Neoplasms
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