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Cited by 73Cardiac pacing and defibrillation studiesCardiac electrophysiology and arrhythmiasCardiovascular Syncope and Autonomic Disorders

Sick Sinus Syndrome Treated with Permanent Pacemaker in 109 Patients: A Follow‐Up Study

Breivik, Kjell, Ohm, Ole‐Jørgen, Segadal, Leidulf·1979·Acta Medica Scandinavica
DOI 10.1111/j.0954-6820.1979.tb13486.x
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Abstract

During the last decade implantation of permanent pacemakers has become the treatment of choice for patients suffering from the sick sinus syndrome (SSS). We have followed up 112 SSS patients treated with permanent pacemakers in Haukeland Hospital in the period 1966--76. The pacemakers were later removed from three of the patients. In the remaining 109 patients the SSS was characterized by tachy-bradyarrhythmias (TBA) in 44 and bradyarrhythmias (BA) in 65. Before implantation, 68 patients had syncopes and 27 severe dizziness. After implantation, symptomatic improvement was apparent in 104 patients; only three still had syncopes. During the follow-up period (mean 34.4 months), 29 patients died (yearly mortality 9.3%). There was no significant difference in total mortality between patients with TBA and with BA. Concomitant disturbances in atrioventricular (AV) conduction occurred in 35.8% of the patients. Among 79 of 80 patients still alive, five had developed total AV block, 19 had stable atrial fibrillation, 12 of these were possibly pacemaker-independent (ventricular rate greater than 60/min). Systemic embolization was observed in 16 patients, more frequently in the TBA (12/44) than in the BA group (4/65) (p less than 0.001). It is concluded that permanent pacemakers have an excellent symptomatic effect in patients with SSS. The prognosis is mainly determined by the presence or absence of coronary heart disease and/or heart failure.

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  • Cardiac pacemaker therapy is indicated and has proved effective in intrinsic sinus node disease when intermittent sinus arrest or sinoatrial block has been demonstrated to account for syncope by ECG documentation during spontaneous syncope.

    “In general, cardiac pacemaker therapy is indicated and has proved effective in intrinsic sinus node disease when intermittent sinus arrest or sinoatrial block has been demonstrated to account for syncope by means of ECG documentation during spontaneous syncope. 334-338”

    From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [335]

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Authors
Breivik, K., Ohm, O., & Segadal, L.
Affiliations
University of Bergen (NO)
Venue
Acta Medica Scandinavica
Publisher
Wiley
Published
1979-01-12
Volume
206
Issue
1-6
Pages
153-159
ISSN
0001-6101 (ISSN-L)
DOI
10.1111/j.0954-6820.1979.tb13486.x
OpenAlex
W1574161168
Cited by
73
References
23
Citations by year
2022: 2 · 2021: 6 · 2019: 1 · 2018: 5 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 2 · 2012: 1
FWCI
3.20
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 11060 d)
Locations
  • Acta Medica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
Keywords
sick sinus syndrome, permanent pacemaker implantation, bradycardia, syncope, atrioventricular block, atrial fibrillation, systemic embolization, mortality, prognosis, coronary artery disease, heart failure
MeSH terms
Adolescent, Adult, Aged, Child, Child, Preschool, Female, Follow-Up Studies, Heart Conduction System, Humans, Male, Middle Aged, Pacemaker, Artificial, Sick Sinus Syndrome

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