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Cited by 381

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Quality of Life Following Breast-Conserving Therapy or Mastectomy: Results of a 5-Year Prospective Study

Engel, Jutta, Kerr, Jacqueline, Schlesinger-Raab, Anne, Sauer, Hansjorg, Holzel, Dieter·2004·The Breast Journal
DOI 10.1111/j.1075-122x.2004.21323.x
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Abstract

There are many conflicting results in the literature comparing quality of life following breast-conserving therapy (BCT) and mastectomy. This study compared long-term quality of life between breast cancer patients treated by BCT or mastectomy in three age groups. Patients (n = 990) completed a quality of life survey, including the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30), at regular intervals over 5 years. In the cross-sectional data, mastectomy patients had significantly (p < 0.01) lower body image, role, and sexual functioning scores and their lives were more disrupted than BCT patients. Emotional and social functioning and financial and future health worries were significantly (p < 0.01) worse for younger patients. There were no differences in body image and lifestyle scores between age groups. There was also no interaction between age and surgery method. Even patients > or =70 years of age reported higher body image and lifestyle scores when treated with BCT. The repeated measures analysis indicated that four functioning scores, half the symptom scores, future health, and global quality of life improved significantly (p < 0.01) over time. All these variables increased significantly for BCT patients and those 50 to 69 years of age. Body image, sexual functioning, and lifestyle disruption scores did not improve over time. BCT should be encouraged in all age groups. Coping with appearance change should be addressed in patient interventions.

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Metadata

Authors
Engel, J., Kerr, J., Schlesinger-Raab, A., Sauer, H., & Holzel, D.
Venue
The Breast Journal
Publisher
Hindawi Limited
Published
2004-05
Volume
10
Issue
3
Pages
223-231
ISSN
  • 1075-122X (ISSN-L)
  • 1524-4741
DOI
10.1111/j.1075-122x.2004.21323.x
OpenAlex
W1991772350
Cited by
381
References
34
FWCI
6.90
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Quality of Life Following Breast-Conserving Therapy or Mastectomy: Results of a 5-Year Prospective Study. https://app.cochat.ai/papers/10.1111/j.1075-122x.2004.21323.x
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Engel, J., Kerr, J., Schlesinger-Raab, A., Sauer, H., & Holzel, D. (2004). Quality of Life Following Breast-Conserving Therapy or Mastectomy: Results of a 5-Year Prospective Study. The Breast Journal. https://doi.org/10.1111/j.1075-122x.2004.21323.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.