Persistent post-mastectomy pain: risk factors and current approaches to treatment

Tait, Raymond C.; Zoberi, Kim; Ferguson, McKenzie; Levenhagen, Kimberly; Luebbert, Rebecca A.; Rowland, Kevin; Salsich, Gretchen B.; Herndon, Christopher

doi:10.1016/j.jpain.2018.06.002

Cited by 190Anesthesia and Pain ManagementCancer survivorship and carePain Management and Treatment

Persistent post-mastectomy pain: risk factors and current approaches to treatment

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Tait, Raymond C., Zoberi, Kim, Ferguson, McKenzie, Levenhagen, Kimberly, Luebbert, Rebecca A., Rowland, Kevin, Salsich, Gretchen B., Herndon, Christopher·2018·The Journal of Pain

DOI 10.1016/j.jpain.2018.06.002PMC PMC6530598

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Abstract

Persistent Post-Mastectomy Pain (PPMP) is a common condition that can follow surgeries for breast cancer, the most common cancer in women. Because of the frequency of PPMP and its potential severity, it has received increasing research attention. This manuscript reviews the recent research literature, beginning with a brief history and then relevant medical, surgical, demographic, and psychosocial risk factors. Subsequently, social, psychological, and functional sequelae that have been linked to PPMPS are considered, as is research on current pharmacological, psychological, and rehabilitative approaches to treatment. The review concludes with a discussion of directions for future research and treatment that might reduce the incidence and impact of PPMP on breast cancer survivors. PERSPECTIVE: This article describes current research literature involving mechanisms, risks, and treatments related to persistent post-mastectomy pain. Implications of research findings also are discussed for pre- and post-surgical approaches to pain management, current treatments, and promising research directions.

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Catastrophic thinking is associated with increased pain sensitivity and central sensitization.
“and increased pain sensitivity and central sensitization4, 16”
From Improving well-being for individuals with persistent pain after surgery for breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ: A randomized clinical trial (2022) · cites this paper as [4]
The Discussion links pain catastrophizing to a possible pathway involving pain sensitivity, but does not establish a direct association. The Preoperative Risk Factors section discusses central sensitization as a theorized contributor to chronic pain after surgery, without linking it specifically to catastrophic thinking. Page numbers are unavailable in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measured
People with persistent post-surgical pain report greater emotional distress, more interference with daily activities, and worse overall quality of life.
“Individuals experiencing PSP also report heightened emotional distress, interference with daily activities, and poorer overall quality of life4.”
From Improving well-being for individuals with persistent pain after surgery for breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ: A randomized clinical trial (2022) · cites this paper as [4]
The Psychosocial Impairments and Quality of Life section reports negative effects on mood, daily activities, and overall quality of life; its Quality of Life subsection describes impaired daily and customary functioning. These passages concern persistent post-mastectomy pain, so they do not establish the claim for persistent post-surgical pain across surgery types. Page numbers were not supplied. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Persistent breast pain has strong negative psychological effects.
“Persistent breast pain (PBP) is prevalent among breast cancer survivors and has powerful negative psychological consequences.”
From Persistent breast pain in post-surgery breast cancer survivors and women with no history of breast surgery or cancer: associations with pain catastrophizing, perceived breast cancer risk, breast cancer worry, and emotional distress (2019) · cites this paper as [4]
The heightened emotional distress in survivors with persistent breast pain is consistent with prior work.
“The heightened emotional distress in survivors with PBP is consistent with our own prior work and that of others using cross-sectional and longitudinal approaches to examining psychological factors associated with PBP following breast cancer surgery [4, 19, 22, 35], as well as the broader literature on persistent pain following surgery in other clinical contexts [36].”
From Persistent breast pain in post-surgery breast cancer survivors and women with no history of breast surgery or cancer: associations with pain catastrophizing, perceived breast cancer risk, breast cancer worry, and emotional distress (2019) · cites this paper as [4]
Pain catastrophizing is consistently elevated in women with persistent breast pain.
“pain catastrophizing (magnification, helplessness, and rumination about pain) have consistently been found to be elevated in the women with PBP [4, 6, 18, 19].”
From Persistent breast pain in post-surgery breast cancer survivors and women with no history of breast surgery or cancer: associations with pain catastrophizing, perceived breast cancer risk, breast cancer worry, and emotional distress (2019) · cites this paper as [4]

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Long‐Term Effects of Breast Cancer Surgery, Treatment, and Survivor Care
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Prediction of Persistent Pain Severity and Impact 12 Months After Breast Surgery Using Comprehensive Preoperative Assessment of Biopsychosocial Pain Modulators
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Qigong Mind-Body Exercise as a Biopsychosocial Therapy for Persistent Post-Surgical Pain in Breast Cancer: A Pilot Study
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A Critical Theoretical Approach to Cancer Disparities: Breast Cancer and the Social Determinants of Health
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Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
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Predicting postoperative pain following root canal treatment by using artificial neural network evaluation
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Persistent breast pain in post-surgery breast cancer survivors and women with no history of breast surgery or cancer: associations with pain catastrophizing, perceived breast cancer risk, breast cancer worry, and emotional distress
Bovbjerg, D. H., Keefe, F. J., Soo, M. S., Manculich, J., Van Denburg, A., Zuley, M. L., Ahrendt, G. M., Skinner, C. S., Edmond, S. N., & Shelby, R. A. (2019) · Acta Oncologica · doi:10.1080/0284186x.2019.1574023 · Cited by 44 · see citing works
Psychological factors are associated with pain at all time frames after breast cancer surgery: a systematic review with meta-analyses
Moloney, N. A., Pocovi, N. C., Dylke, E. S., Graham, P. L., & De Groef, A. (2021) · Pain Medicine · doi:10.1093/pm/pnaa363 · Cited by 43 · see citing works
Effect of sentinel lymph node biopsy on upper limb function in women with early breast cancer: A systematic review of clinical trials
Pilger, T. L., Francisco, D. F., & dos Reis, F. J. C. (2021) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2021.01.024 · Cited by 35 · see citing works
Ultrasound-Guided Pectoral Nerve Block I and Serratus-Intercostal Plane Block Alleviate Postoperative Pain in Patients Undergoing Modified Radical Mastectomy
Wang, W. (2019) · Pain Physician · doi:10.36076/ppj/2019.22.e315 · Cited by 32 · see citing works
Psychological resilience associates with pain experience in women treated for breast cancer
Liesto, S., Sipilä, R. M., Aho, T., Harno, H., Hietanen, M., & Kalso, E. A. (2020) · Scandinavian Journal of Pain · doi:10.1515/sjpain-2019-0137 · Cited by 33 · see citing works
“Making Peace with Our Bodies”: A Qualitative Analysis of Breast Cancer Survivors' Experiences with Qigong Mind–Body Exercise
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Effect of perioperative pain neuroscience education in patients with post-mastectomy persistent pain: a retrospective, propensity score-matched study
Manfuku, M., Nishigami, T., Mibu, A., Yamashita, H., Imai, R., Tanaka, K., Kitagaki, K., Kanamori, H., & Sumiyoshi, K. (2021) · Supportive Care in Cancer · doi:10.1007/s00520-021-06103-1 · Cited by 31 · see citing works
Machine Learning Predicts Patient Tangible Outcomes After Dental Implant Surgery
Yadalam, P. K., Trivedi, S. S., Krishnamurthi, I., Anegundi, R. V., Mathew, A., Shayeb, M. A., Jayaraj, K. N., Jaber, M. A., & Rajkumar, R. (2022) · IEEE Access · doi:10.1109/access.2022.3228793 · Cited by 30 · see citing works
Breast cancer survivorship needs: a qualitative study
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Post-Breast Surgery Pain Syndrome: Shifting a Surgical Paradigm
Beederman, M. R., & Bank, J. (2021) · Plastic & Reconstructive Surgery Global Open · doi:10.1097/gox.0000000000003720 · Cited by 29 · see citing works
The long-term burden of a symptom cluster and association with longitudinal physical and emotional functioning in breast cancer survivors
Ebbestad, F. E., Ammitzbøll, G., Horsbøl, T. A., Andersen, I., Johansen, C., Zehran, B., & Dalton, S. O. (2023) · Acta Oncologica · doi:10.1080/0284186x.2023.2185909 · Cited by 26 · see citing works
Prolonged Opioid Use After Surgery for Early-Stage Breast Cancer
Shen, C., Thornton, J. D., Gu, D., Dodge, D. G., Zhou, S., He, W., Zhao, H., & Giordano, S. H. (2020) · The Oncologist · doi:10.1634/theoncologist.2019-0868 · Cited by 26 · see citing works
Post-Mastectomy Pain: An Updated Overview on Risk Factors, Predictors, and Markers
Calapai, M., Esposito, E., Puzzo, L., Vecchio, D. A., Blandino, R., Bova, G., Quattrone, D., Mannucci, C., Ammendolia, I., Mondello, C., et al. (2021) · Life · doi:10.3390/life11101026 · Cited by 25 · see citing works
Postmastectomy Functional Impairments
Marco, E., Trépanier, G., Chang, E. B., Mauti, E., Jones, J. M., & Zhong, T. (2023) · Current Oncology Reports · doi:10.1007/s11912-023-01474-6 · Cited by 24 · see citing works
Effectiveness of Combined Complex Decongestive Therapy and Resistance Exercises in the Treatment of Lymphedema Associated with Breast Cancer and the Effect of Pain on Treatment Response
Çorum, M., Başoğlu, C., Korkmaz, M. D., Yildirim, M., & Öneş, K. (2021) · Lymphatic Research and Biology · doi:10.1089/lrb.2020.0099 · Cited by 24 · see citing works
Disparities in Breast-Conserving Therapy for Non-Hispanic American Indian/Alaska Native Women Compared with Non-Hispanic White Women
Erdrich, J., Cordova-Marks, F. M., Monetathchi, A. R., Wu, M., White, A. L., & Melkonian, S. C. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-10730-7 · Cited by 23 · see citing works
Sensory Outcomes after Neurotization in Nipple-sparing Mastectomy and Implant-based Breast Reconstruction
Peled, A. W., von Eyben, R., & Peled, Z. M. (2023) · Plastic & Reconstructive Surgery Global Open · doi:10.1097/gox.0000000000005437 · Cited by 23 · see citing works
An Interventional Pain Algorithm for the Treatment of Postmastectomy Pain Syndrome: A Single-Center Retrospective Review
Yang, A. H., Nadav, D., Legler, A., Chen, G. H., Hingula, L. P., Puttanniah, V. G., & Gulati, A. (2020) · Pain Medicine · doi:10.1093/pm/pnaa343 · Cited by 23 · see citing works
Comprehensive Review on Personalized Pain Assessment and Multimodal Interventions for Postoperative Recovery Optimization
Xu, J., Liu, X., Zhao, J., Zhao, J., Li, H., Ye, H., & Ai, S. (2025) · Journal of Pain Research · doi:10.2147/jpr.s516249 · Cited by 37 · see citing works
Pain Management in Breast Cancer Patients: A Multidisciplinary Approach
Alhazmi, L. S. S., Bawadood, M., Aljohani, A. M. S., Alzahrani, A. A. R., Moshref, L. H., Trabulsi, N. H., & Moshref, R. H. (2021) · Cureus · doi:10.7759/cureus.15994 · Cited by 24 · see citing works
Society of Surgical Oncology Breast Disease Site Working Group Statement on Contralateral Mastectomy: Indications, Outcomes, and Risks
Singh, P., Agnese, D. M., Amin, M., Barrio, A. V., van den Bruele, A. B., Burke, E. E., Danforth, D. N., Dirbas, F. M., Eladoumikdachi, F. G., Kantor, O., et al. (2024) · Annals of Surgical Oncology · doi:10.1245/s10434-024-14893-x · Cited by 21 · see citing works
Autonomic Regulation of Nociceptive and Immunologic Changes in a Mouse Model of Complex Regional Pain Syndrome
Sahbaie, P., Li, W., Guo, T., Shi, X., Kingery, W. S., & Clark, J. D. (2021) · Journal of Pain · doi:10.1016/j.jpain.2021.09.009 · Cited by 21 · see citing works
Incidence, risk factors, prevention and treatment of postmastectomy pain syndrome in breast cancer: A multicenter study
Ren, Y., Kong, X., Yang, Q., Ouyang, L., Liu, Q., Dong, H., Wang, Z., Fang, Y., & Wang, J. (2022) · International Journal of Surgery · doi:10.1016/j.ijsu.2022.106937 · Cited by 21 · see citing works
Postmastectomy Pain Syndrome: A Narrative Review
Salati, S. A., AlSulaim, L. S., Alharbi, M. H., Alharbi, N., Alsenaid, T. M., Alaodah, S. A., Alsuhaibani, A. S., & Albaqami, K. A. (2023) · Cureus · doi:10.7759/cureus.47384 · Cited by 25 · see citing works
Persistent Pain After Breast Cancer Treatment, an Underreported Burden for Breast Cancer Survivors
Strijbos, B. T. M., Janssen, L., Voogd, A. C., Zwaans, W. A. R., Roumen, R. M. H., & Maaskant-Braat, A. J. G. (2024) · Annals of Surgical Oncology · doi:10.1245/s10434-024-15682-2 · Cited by 24 · see citing works
AAAPT Diagnostic Criteria for Acute Pain Following Breast Surgery
Schreiber, K. L., Belfer, I., Miaskowski, C. A., Schumacher, M. A., Stacey, B. R., & de Ven, T. V. (2019) · Journal of Pain · doi:10.1016/j.jpain.2019.08.008 · Cited by 20 · see citing works
Pre-surgery supportive and goal-oriented strategies are associated with lower post-surgery perceived distress in women diagnosed with breast cancer
Taurisano, P., Abbatantuono, C., Verri, V., Pepe, I., Stucci, L. S., Taurino, A., Moschetta, M., De Caro, M. F., & Antonucci, L. A. (2022) · BMC Psychology · doi:10.1186/s40359-021-00714-3 · Cited by 19 · see citing works
Pain Control After Mastectomy in Transgender Patients: Ultrasound-guided Pectoral Nerve Block II Versus Conventional Intercostal Nerve Block: A Randomized Clinical Trial
Rokhtabnak, F., Sayad, S., Izadi, M., Motlagh, S. D., & Rahimzadeh, P. (2021) · Anesthesiology and Pain Medicine · doi:10.5812/aapm.119440 · Cited by 20 · see citing works
Effects of Transcutaneous Electrical Nerve Stimulation on Mastectomy Pain, Patient Satisfaction, and Patient Outcomes
Erden, S., Yurtseven, Ş., Demir, S. G., Arslan, S., Arslan, Ü., & Dalcı, K. (2022) · Journal of PeriAnesthesia Nursing · doi:10.1016/j.jopan.2021.08.017 · Cited by 18 · see citing works
Approaches to Opioid Prescribing in Cancer Survivors: Lessons Learned from the General Literature
Jones, K., & Merlin, J. (2021) · Cancer · doi:10.1002/cncr.33961 · Cited by 16 · see citing works
Predictive factors for patients who need treatment for chronic post-surgical pain (CPSP) after breast cancer surgery
Uemoto, Y., Uchida, M., Kondo, N., Wanifuchi‐Endo, Y., Fujita, T., Asano, T., Hisada, T., Nishikawa, S., Katagiri, Y., Terada, M., et al. (2021) · Breast Cancer · doi:10.1007/s12282-021-01275-4 · Cited by 16 · see citing works
Comparison of the Efficacy of Ultrasound Guided Serratus Anterior Plane Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Modified Radical Mastectomy: A Randomised Controlled Trial
Ahuja, D., Kumar, V., Gupta, N., Bharati, S. J., Garg, R. K., Mishra, S., Khan, M. A., & Bhatnagar, S. (2022) · doi:10.5152/tjar.2022.21127 · Cited by 15 · see citing works
Patient-reported health-related quality of life outcomes following mastectomy for breast cancer, with immediate, delayed or no breast reconstruction: Four-year follow-up from a prospective cohort study
Dempsey, K., Mathieu, E., Brennan, M. E., Snook, K., Hoffman, J., Campbell, I., Scarlet, J., Flay, H., Wong, A., Boyle, F. M., et al. (2023) · The Breast · doi:10.1016/j.breast.2023.08.001 · Cited by 13 · see citing works
Effectiveness of an Adapted Physical Activity Protocol for Upper Extremity Recovery and Quality of Life Improvement in a Case of Seroma after Breast Cancer Treatment
Mirandola, D., Maestrini, F., Carretti, G., Manetti, M., & Marini, M. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17217727 · Cited by 14 · see citing works
Qigong Training Positively Impacts Both Posture and Mood in Breast Cancer Survivors With Persistent Post-surgical Pain: Support for an Embodied Cognition Paradigm
Quixadá, A. P., Miranda, J., Osypiuk, K., Bonato, P., Vergara-Diaz, G., Ligibel, J., Mehling, W., Thompson, E., & Wayne, P. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.800727 · Cited by 10 · see citing works
Impact of Virtual Reality on Pain, ROM, Muscle Strength and Quality of Life among Breast Cancer Patients: An Integrative Review of Literature
Sharma, A., Sharma, N., & Chahal, A. (2024) · Pain Management Nursing · doi:10.1016/j.pmn.2024.04.015 · Cited by 13 · see citing works
The relationship between anger regulation, mood, pain, and pain‐related disability in women treated for breast cancer
Sipilä, R. M., Hintsa, T., Lipsanen, J. O., Tasmuth, T., Estlander, A., & Kalso, E. A. (2019) · Psycho-Oncology · doi:10.1002/pon.5182 · Cited by 13 · see citing works
Effect of perioperative cognitive behavioural therapy on chronic post-surgical pain among breast cancer patients with high pain catastrophising characteristics: protocol for a double-blinded randomised controlled trial
Moorthy, A., Lowry, D., Edgley, C., Casey, M., & Buggy, D. J. (2022) · Trials · doi:10.1186/s13063-022-06019-z · Cited by 13 · see citing works
A Review on the Management of Peripheral Neuropathic Pain Following Breast Cancer
Ávila, F. R., Torres‐Guzman, R. A., Maita, K. C., Garcia, J. P., Velasquez, G. D. D. S., Borna, S., Ho, O. A., & Forte, A. J. (2023) · Breast Cancer Targets and Therapy · doi:10.2147/bctt.s386803 · Cited by 13 · see citing works
The Effects of Massage Therapy in Decreasing Pain and Anxiety in Post-Surgical Patients With Breast Cancer: A Systematic Review and Meta-Analysis
Cole, J. S., Olson, A. D., & Dupont‐Versteegden, E. E. (2024) · Global Advances in Integrative Medicine and Health · doi:10.1177/27536130241245099 · Cited by 12 · see citing works
Exclusion of older adults from clinical trials in cancer-related pain
Krysa, K., Kowalczyk, E., Borysowski, J., Lachota, M., & Pasierski, T. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.945481 · Cited by 12 · see citing works
Effects of Physical Exercise and Motor Activity on Oxidative Stress and Inflammation in Post-Mastectomy Pain Syndrome
Calapai, M., Puzzo, L., Bova, G., Vecchio, D. A., Blandino, R., Barbagallo, A., Ammendolia, I., Cardia, L., Pasquale, M. D., Calapai, F., et al. (2023) · Antioxidants · doi:10.3390/antiox12030643 · Cited by 13 · see citing works
Neurotrophin-3 (NT-3) as a Potential Biomarker of the Peripheral Nervous System Damage Following Breast Cancer Treatment
Tonyan, S. N., Pospelova, M. L., Krasnikova, V. V., Fionik, O. V., Alekseeva, T. M., Samochernykh, K. A., Ivanova, N., Вавилова, Т. В., Vasilieva, E. Y., Makhanova, A. M., et al. (2023) · Pathophysiology · doi:10.3390/pathophysiology30020010 · Cited by 11 · see citing works
Ultrasound-guided superficial serratus plane block for persistent post-mastectomy pain: four case reports
Liu, Q., Khanna, A. K., Stubblefield, M. D., Yue, G. H., & Allexandre, D. (2021) · Supportive Care in Cancer · doi:10.1007/s00520-021-06696-7 · Cited by 11 · see citing works
Effect of intravenous lidocaine on chronic postoperative pain in patients undergoing breast cancer surgery: a prospective, double-blind, randomized, placebo-controlled clinical trial
Xia, M., Wei, Q., Zhang, Q., & Jiang, H. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-3522 · Cited by 11 · see citing works
Association of psychological distress with arm morbidity symptoms in breast cancer survivors: outcomes from the use of PHQ-9 and GAD-7 questionnaires
Yusof, K. M., Sidik, S. M., Mahmud, R., Abdullah, M., Avery‐Kiejda, K. A., & Rosli, R. (2023) · Breast Cancer · doi:10.1007/s12282-023-01475-0 · Cited by 10 · see citing works
Hyperbaric Oxygen Therapy for Complications in Nipple-Sparing Mastectomy with Breast Reconstruction: A Systematic Review
Idris, O. A., Ahmedfiqi, Y. O., Shebrain, A., Al-Assil, T., Pacione, S. C., Haj, D., Motan, A. D., Momani, F., Bzizi, H. F., Jahromi, B. S., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13123535 · Cited by 10 · see citing works
Paravertebral versus Pectoralis-II (Interpectoral and Pectoserratus) Nerve Blocks for Postoperative Analgesia after Nonmastectomy Breast Surgery: A Randomized, Controlled, Observer-masked Noninferiority Trial
Gabriel, R. A., Curran, B. P., Swisher, M. W., Sztain, J. F., Tsuda, P. S., Said, E. T., Alexander, B. S., Finneran, J. J., Abramson, W. B., Black, J. R., et al. (2024) · Anesthesiology · doi:10.1097/aln.0000000000005207 · Cited by 10 · see citing works
Efficacy of transcranial direct current stimulation (tDCS) on pain and shoulder range of motion in post-mastectomy pain syndrome patients: a randomized-control trial
Hanna, M. H. Z., Rezkallah, S. S., Shalaby, A. S., & Hanna, M. Z. (2023) · Bulletin of Faculty of Physical Therapy · doi:10.1186/s43161-022-00116-5 · Cited by 10 · see citing works
Erector spinae plane block and rhomboid intercostal block for the treatment of post-mastectomy pain syndrome
Piraccini, E., Calli, M., Taddei, S., & Maitan, S. (2020) · Saudi Journal of Anaesthesia · doi:10.4103/sja.sja_203_20 · Cited by 10 · see citing works
Chinese Association for the Study of Pain: Expert consensus on chronic postsurgical pain
Liu, Y., Feng, Y., Liu, Y., Lv, Y., Xiong, Y.-C., Ma, K., Zhang, X., Liu, J., Jin, Y., Bao, H., et al. (2021) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i9.2090 · Cited by 10 · see citing works
Persistent post-surgical pain and its relationship to health-related quality of life in Pakistani women after breast cancer surgery
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Post Surgical Pain Following Breast Cancer
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Authors: Tait, R. C., Zoberi, K., Ferguson, M., Levenhagen, K., Luebbert, R. A., Rowland, K., Salsich, G. B., & Herndon, C.
Affiliations: Saint Louis University (ES)
Southern Illinois University Edwardsville (US)
Saint Louis University (US)
Corresponding author: Tait, Raymond C.
ORCID: Tait, Raymond C.
Ferguson, McKenzie
Luebbert, Rebecca A.
Rowland, Kevin
Salsich, Gretchen B.
Herndon, Christopher
Venue: The Journal of Pain
Publisher: Elsevier BV
Published: 2018-12
Volume: 19
Issue: 12
Pages: 1367-1383
ISSN: 1526-5900 (ISSN-L)
DOI: 10.1016/j.jpain.2018.06.002
PMC: PMC6530598
OpenAlex: W2811450224
Cited by: 190
References: 178
Citations by year: 2026: 15 · 2025: 27 · 2024: 29 · 2023: 27 · 2022: 28 · 2021: 34 · 2020: 20 · 2019: 10
FWCI: 3.56
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1745 d)
Locations: Journal of Pain (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Drug Abuse to the Southern Illinois University – Edwardsville and Saint Louis University Center of Excellence in Pain Education (HHSN271201500056C)
Topics: Health Sciences › Medicine › Surgery › Anesthesia and Pain Management
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Keywords: breast cancer survivors, risk factors, psychosocial risk factors, pain management, pharmacotherapy, psychological intervention, rehabilitation, functional sequelae
MeSH terms: Breast Neoplasms, Female, Humans, Mastectomy, Pain, Postoperative, Postoperative Pain, Risk Factors

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Persistent post-mastectomy pain: risk factors and current approaches to treatment

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